2026 ICD-10-CM Diagnosis Code P74.31Hyperkalemia of newborn

ICD-10-CM Codes›P00–P96›P70-P74›P74

ICD-10-CM P74.31
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

P74.31 is a billable ICD-10-CM diagnosis code for hyperkalemia of newborn. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). Coders also document this condition as hyperkalemia. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified perinatal conditions.

Code Identity

ICD-10-CM Code
P74.31
Billable Status
Yes — Valid for Submission
Code Describes
Hyperkalemia of newborn
Short Description
Hyperkalemia of newborn
Same as the full description in the CMS dataset.
Parent Code
P74.3
Disturbances of potassium balance of newborn

Code Classification

ChapterP00–P96Certain conditions originating in the perinatal period
SectionP70-P74Transitory endocrine and metabolic disorders specific to newborn
CategoryP74Other transitory neonatal electrolyte and metabolic disturbances
This CodeP74.31Hyperkalemia of newborn

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Hyperkalemia
  • Transitory neonatal electrolyte disturbance
  • Transitory neonatal hyperkalemia

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Disturbance(s)
      • electrolyte
        • newborn, transitory
          • potassium balance
            • hyperkalemia
    • Disturbance(s)
      • potassium balance, newborn
        • hyperkalemia
    • Imbalance
      • electrolyte
        • neonatal, transitory NEC
          • potassium
            • hyperkalemia

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR PNL013
Other specified and unspecified perinatal conditions
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Hyperkalemia

    abnormally high potassium concentration in the blood, most often due to defective renal excretion. it is characterized clinically by electrocardiographic abnormalities (elevated t waves and depressed p waves, and eventually by atrial asystole). in severe cases, weakness and flaccid paralysis may occur. (dorland, 27th ed)

  • Pseudohypoaldosteronism

    a heterogeneous group of disorders characterized by renal electrolyte transport dysfunctions. congenital forms are rare autosomal disorders characterized by neonatal hypertension, hyperkalemia, increased renin activity and aldosterone concentration. the type i features hyperkalemia with sodium wasting; type ii, hyperkalemia without sodium wasting. pseudohypoaldosteronism can be the result of a defective renal electrolyte transport protein or acquired after kidney transplantation.

  • Grade 1 Hyperkalemia, CTCAE|Grade 1 Hyperkalemia

    >uln - 5.5 mmol/l

  • Grade 2 Hyperkalemia, CTCAE|Grade 2 Hyperkalemia

    >5.5 - 6.0 mmol/l; intervention initiated

  • Grade 3 Hyperkalemia, CTCAE|Grade 3 Hyperkalemia

    >6.0 - 7.0 mmol/l; hospitalization indicated

  • Grade 1 Hyperkalemia, CTCAE|Grade 1 Hyperkalemia

    >uln-5.5 mmol/l

  • Grade 2 Hyperkalemia, CTCAE|Grade 2 Hyperkalemia

    >5.5-6.0 mmol/l; intervention initiated

  • Grade 3 Hyperkalemia, CTCAE|Grade 3 Hyperkalemia

    >6.0-7.0 mmol/l; hospitalization indicated

  • Grade 4 Hyperkalemia, CTCAE|Grade 4 Hyperkalemia

    >7.0 mmol/l; life-threatening consequences

  • Grade 5 Hyperkalemia, CTCAE|Grade 5 Hyperkalemia

    death

  • Hyperkalemia

    higher than normal levels of potassium in the circulating blood; associated with kidney failure or sometimes with the use of diuretic drugs.

  • Hyperkalemia, CTCAE|Hyperkalemia|Hyperkalemia

    a disorder characterized by laboratory test results that indicate an elevation in the concentration of potassium in the blood; associated with kidney failure or sometimes with the use of diuretic drugs.

  • Hyperkalemic Mineralocorticoid Resistance|Chloride Shunt Syndrome|Familial Hyperkalemic Hypertension|Gordon Hyperkalemia|Mineralocorticoid Resistant Hyperkalemia|PHA Type 2|Pseudohypoaldosteronism, Type II|Spitzer-Weinstein Syndrome

    a genetically heterogynous condition characterized by hyperkalemia, hyperchloremic acidosis, low or suppressed renin activity, and normal to high concentrations of aldosterone. mutations in genes (for example wnk1 or wnk4), regulating na-cl cotransporters (ncc), na-k-cl cotransporters (nkcc2), or the renal outer medullary potassium (romk) channel have been identified as causative in this condition. the primary abnormality is thought to be a specific defect of the renal secretory mechanism for potassium, which limits the kaliuretic response to, but not the sodium and chloride reabsorptive effect of, mineralocorticoid.

  • Hyperkalemic Mineralocorticoid Resistance|Chloride Shunt Syndrome|Familial Hyperkalemic Hypertension|Gordon Hyperkalemia|Mineralocorticoid Resistant Hyperkalemia|PHA Type 2|Pseudohypoaldosteronism, Type II|Spitzer-Weinstein Syndrome

    a genetically heterogenous condition characterized by hyperkalemia, hyperchloremic acidosis, low or suppressed renin activity, and normal to high concentrations of aldosterone. mutations in genes (for example wnk1 or wnk4), regulating na-cl cotransporters (ncc), na-k-cl cotransporters (nkcc2), or the renal outer medullary potassium (romk) channel have been identified as causative in this condition. the primary abnormality is thought to be a specific defect of the renal secretory mechanism for potassium, which limits the kaliuretic response to, but not the sodium and chloride reabsorptive effect of, mineralocorticoid.

Patient EducationClinical

Fluid and Electrolyte Balance

Electrolytes are minerals that have an electric charge when they are dissolved in water or body fluids, including blood. The electric charge can be positive or negative. You have electrolytes in your blood, urine (pee), tissues, and other body fluids.

The full article covers:

  • What are electrolytes?
  • What are the different types of electrolytes in your body?
  • What is an electrolyte imbalance?
  • What are the different types of electrolyte imbalances?
  • How are electrolyte imbalances diagnosed?
  • What are the treatments for electrolyte imbalances?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code History & ChangesHistory

Replacement P74.31 replaces the following previously assigned code(s):

  • P74.3 - Disturbances of potassium balance of newborn
FY 2019AddedAdded to the ICD-10-CM code setEffective October 1, 2018.
FY 2020–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About P74.31Overview

Is P74.31 (Disturbances of potassium balance of newborn) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report hyperkalemia of newborn on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.