2027 ICD-10-CM Diagnosis Code P35.1Congenital cytomegalovirus infection
ICD-10-CM Codes›P00–P96›P35-P39›P35
- Billable — Valid for Submission
- MCC — Major Complication or Comorbidity
- Chronic Condition
P35.1 is a billable ICD-10-CM diagnosis code for congenital cytomegalovirus infection. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 791, 793. As a secondary diagnosis, it counts as a major complication or comorbidity (MCC) and places an inpatient stay in the highest severity level of its MS-DRG family. It does not count, however, when the principal diagnosis is one of 31 closely related codes. Coders also document this condition as chronic congenital cytomegalic inclusion disease. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Perinatal infections and Viral infection.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Chronic congenital cytomegalic inclusion disease
- Congenital cytomegalovirus infection
- Congenital infection caused by Herpes virus
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to P35.1: its own notes plus those printed at P35, block P35-P39, and Chapter 16. A note printed at a category, block or chapter applies to every code under it.
Includes
Further defines, or gives examples of, the content of the category.
- infections acquired in utero or during birth
- conditions that have their origin in the fetal or perinatal period (before birth through the first 28 days after birth) even if morbidity occurs later
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
- asymptomatic human immunodeficiency virus [HIV] infection status (Z21)
- congenital gonococcal infection (A54.-)
- congenital pneumonia (P23.-)
- congenital syphilis (A50.-)
- human immunodeficiency virus [HIV] disease (B20)
- infant botulism (A48.51)
- infectious diseases not specific to the perinatal period (A00-B99, J09, J10.-)
- intestinal infectious disease (A00-A09)
- laboratory evidence of human immunodeficiency virus [HIV] (R75)
- tetanus neonatorum (A33)
Notes
General instructions on how these codes are used.
- Codes from this chapter are for use on newborn records only, never on maternal records
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Referenced in Other NotesGuidance
Instructional notes printed at other codes that name P35.1, its category, or a range that includes it.
Excludes1 1
These codes carry an Excludes1 note naming P35.1: they are not reported together with it, unless the two conditions are unrelated.
- B25 Cytomegaloviral diseasecongenital cytomegalovirus infection (P35.1)
Excludes2 2
These codes carry an Excludes2 note naming P35.1: its condition is not part of those codes, and both may be reported when the patient has both.
- Chapter 1 (A00-B99) Certain infectious and parasitic diseases
- P00.2 Newborn affected by maternal infectious and parasitic diseases
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Disease, diseased See Also: Syndrome;
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Patient EducationClinical
Cytomegalovirus Infections
Cytomegalovirus (CMV) is a virus found around the world. It is related to the viruses that cause chickenpox and infectious mononucleosis (mono). Between 50% and 80% of adults in the United States have had a CMV infection by age 40. Once CMV is in a person's body, it stays there for life.
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert P35.1 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About P35.1Overview
What is the ICD-10 code for congenital cytomegalovirus infection?
The ICD-10-CM code for congenital cytomegalovirus infection is P35.1 (sometimes written as P351). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is P35.1 (Congenital viral diseases) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report congenital cytomegalovirus infection on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does P35.1 group to?
When congenital cytomegalovirus infection is the principal diagnosis on an inpatient stay, it groups to MS-DRG 793, 791, with relative weights from 4.1073 to 4.2192 depending on complications. Higher weights mean higher Medicare reimbursement.
Is P35.1 a CC or MCC?
CMS lists P35.1 as an MCC (major complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it places the inpatient stay in the highest-weighted DRG of its severity family. It does not count when the principal diagnosis is one of the 31 closely related codes in its exclusion list.
What is the ICD-9 equivalent of P35.1?
Under the General Equivalence Mappings, congenital cytomegalovirus infection converts to ICD-9-CM 771.1 (cong cytomegalovirus inf). The mapping is a direct match.
