2027 ICD-10-CM Diagnosis Code B25Cytomegaloviral disease

ICD-10-CM Codes›A00–B99›B25-B34›B25

ICD-10-CM B25
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

B25 is a non-billable ICD-10-CM category code for cytomegaloviral disease, so it cannot be submitted on claims. Use a more specific code from this category instead, such as B25.0, B25.1, B25.2, and B25.8.

Code Identity

ICD-10-CM Code
B25
Billable Status
No — Non-Billable Category
Code Describes
Cytomegaloviral disease
Short Description
Cytomegaloviral disease
Same as the full description in the CMS dataset.
Chapter
B25-B34
Other viral diseases

Code Classification

ChapterA00–B99Certain infectious and parasitic diseases
SectionB25-B34Other viral diseases
CategoryB25Cytomegaloviral disease
This CodeB25Cytomegaloviral disease

Specific Coding for Cytomegaloviral diseaseOverview

Non-specific codes like B25 require more characters. Use one of these billable codes instead:

  • Use B25.0 for Cytomegaloviral pneumonitis

  • Use B25.1 for Cytomegaloviral hepatitis

  • Use B25.2 for Cytomegaloviral pancreatitis

  • Use B25.8 for Other cytomegaloviral diseases

  • Use B25.9 for Cytomegaloviral disease, unspecified

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to B25: its own notes plus those printed at Chapter 1. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From Chapter 1 (A00-B99) Certain infectious and parasitic diseases applies to 1,068 codes
  • diseases generally recognized as communicable or transmissible

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

  • congenital cytomegalovirus infection (P35.1)
  • cytomegaloviral mononucleosis (B27.1-)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Chapter 1 (A00-B99) Certain infectious and parasitic diseases applies to 1,068 codes
  • carrier or suspected carrier of infectious disease (Z22.-)
  • certain localized infections - see body system-related chapters
  • infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium (O98.-)
  • infectious and parasitic diseases specific to the perinatal period (P35-P39)
  • influenza and other acute respiratory infections (J00-J22)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

From Chapter 1 (A00-B99) Certain infectious and parasitic diseases applies to 1,068 codes
  • code to identify resistance to antimicrobial drugs (Z16.-)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name B25, its category, or a range that includes it.

Applicable To 1

These notes mention B25.

  • O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium
    Conditions in A80-B09, B25-B34, R87.81-, R87.82-

Excludes2 1

These codes carry an Excludes2 note naming B25: its condition is not part of those codes, and both may be reported when the patient has both.

  • B10 Other human herpesviruses
    human herpesvirus 5 (B25.-)

Use Additional Code 1

These codes say to use an additional code from the note, and B25 is one of the codes named.

  • T86.43 Liver transplant infection
    Cytomegalovirus (CMV) infection (B25.-)

Patient EducationClinical

Cytomegalovirus Infections

Cytomegalovirus (CMV) is a virus found around the world. It is related to the viruses that cause chickenpox and infectious mononucleosis (mono). Between 50% and 80% of adults in the United States have had a CMV infection by age 40. Once CMV is in a person's body, it stays there for life.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About B25Overview

What is the ICD-10 code for cytomegaloviral disease?

B25 is the ICD-10-CM category for cytomegaloviral disease, but it is a non-billable header: claims need a more specific code from this category, listed on this page.

Is B25 (Cytomegaloviral disease) a billable code?

No. This is a category header that groups the codes for cytomegaloviral disease, and headers cannot be submitted on claims. Claims for cytomegaloviral disease need a more specific code from this category, such as B25.0, B25.1, and B25.2.

Can B25 be reported with P35.1?

Not as a rule. The Excludes1 note on B25 lists "congenital cytomegalovirus infection (P35.1)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).