2027 ICD-10-CM Diagnosis Code P25.0Interstitial emphysema originating in the perinatal period
ICD-10-CM Codes›P00–P96›P19-P29›P25
- Billable — Valid for Submission
- MCC — Major Complication or Comorbidity
- Not Chronic
P25.0 is a billable ICD-10-CM diagnosis code for interstitial emphysema originating in the perinatal period. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 791, 793. As a secondary diagnosis, it counts as a major complication or comorbidity (MCC) and places an inpatient stay in the highest severity level of its MS-DRG family. It does not count, however, when the principal diagnosis is one of 78 closely related codes. Coders also document this condition as bilateral congenital lobar emphysema. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Respiratory perinatal condition.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Bilateral congenital lobar emphysema
- Bronchial atresia with segmental pulmonary emphysema
- Congenital atresia of bronchus
- Congenital emphysema
- Congenital lobar emphysema
- Interstitial emphysema of lung
- Perinatal interstitial emphysema
- Subcutaneous emphysema
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to P25.0: its own notes plus those printed at Chapter 16. A note printed at a category, block or chapter applies to every code under it.
Includes
Further defines, or gives examples of, the content of the category.
- conditions that have their origin in the fetal or perinatal period (before birth through the first 28 days after birth) even if morbidity occurs later
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
Notes
General instructions on how these codes are used.
- Codes from this chapter are for use on newborn records only, never on maternal records
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Referenced in Other NotesGuidance
Instructional notes printed at other codes that name P25.0, its category, or a range that includes it.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Patient EducationClinical
Lung Diseases
When you breathe, your lungs take in oxygen from the air and deliver it to the bloodstream. The cells in your body need oxygen to work and grow. During a normal day, you breathe nearly 25,000 times. People with lung disease have difficulty breathing. Millions of people in the U.S. have lung disease.
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert P25.0 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About P25.0Overview
What is the ICD-10 code for interstitial emphysema originating in the perinatal period?
The ICD-10-CM code for interstitial emphysema originating in the perinatal period is P25.0 (sometimes written as P250). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is P25.0 a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report interstitial emphysema originating in the perinatal period on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does P25.0 group to?
When interstitial emphysema originating in the perinatal period is the principal diagnosis on an inpatient stay, it groups to MS-DRG 793, 791, with relative weights from 4.1073 to 4.2192 depending on complications. Higher weights mean higher Medicare reimbursement.
Is P25.0 a CC or MCC?
CMS lists P25.0 as an MCC (major complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it places the inpatient stay in the highest-weighted DRG of its severity family. It does not count when the principal diagnosis is one of the 78 closely related codes in its exclusion list.
What is the ICD-9 equivalent of P25.0?
Under the General Equivalence Mappings, interstitial emphysema originating in the perinatal period converts to ICD-9-CM 770.2 (NB interstit emphysema). The mapping is approximate, so confirm the match fits the documentation.
