2026 ICD-10-CM Diagnosis Code P25.0Interstitial emphysema originating in the perinatal period

ICD-10-CM Codes›P00–P96›P19-P29›P25

ICD-10-CM P25.0
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

P25.0 is a billable ICD-10-CM diagnosis code for interstitial emphysema originating in the perinatal period. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). Coders also document this condition as bilateral congenital lobar emphysema. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Respiratory perinatal condition.

Code Identity

ICD-10-CM Code
P25.0
Billable Status
Yes — Valid for Submission
Code Describes
Interstitial emphysema originating in the perinatal period
Short Description
Interstitial emphysema originating in the perinatal period
Same as the full description in the CMS dataset.
Parent Code
P25
Interstitial emphysema and related conditions originating in the perinatal period

Code Classification

ChapterP00–P96Certain conditions originating in the perinatal period
SectionP19-P29Respiratory and cardiovascular disorders specific to the perinatal period
CategoryP25Interstitial emphysema and related conditions originating in the perinatal period
This CodeP25.0Interstitial emphysema originating in the perinatal period

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Bilateral congenital lobar emphysema
  • Bronchial atresia with segmental pulmonary emphysema
  • Congenital atresia of bronchus
  • Congenital emphysema
  • Congenital lobar emphysema
  • Interstitial emphysema of lung
  • Perinatal interstitial emphysema
  • Subcutaneous emphysema

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Emphysema(atrophic) (bullous) (chronic) (interlobular) (lung) (obstructive) (pulmonary) (senile) (vesicular)
      • congenital (interstitial)
    • Emphysema(atrophic) (bullous) (chronic) (interlobular) (lung) (obstructive) (pulmonary) (senile) (vesicular)
      • interstitial
        • congenital
    • Emphysema(atrophic) (bullous) (chronic) (interlobular) (lung) (obstructive) (pulmonary) (senile) (vesicular)
      • interstitial
        • perinatal period

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR PNL006
Respiratory perinatal condition
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Subcutaneous Emphysema

    presence of air or gas in the subcutaneous tissues of the body.

  • Grade 3 Subcutaneous Emphysema, CTCAE|Grade 3 Subcutaneous emphysema

    severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self-care adl or severe impact on age-appropriate normal daily activity (pediatric)

  • Grade 1 Subcutaneous Emphysema, CTCAE|Grade 1 Subcutaneous emphysema

    asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated

  • Grade 2 Subcutaneous Emphysema, CTCAE|Grade 2 Subcutaneous emphysema

    moderate; minimal, local or noninvasive intervention indicated

  • Grade 3 Subcutaneous Emphysema, CTCAE|Grade 3 Subcutaneous emphysema

    severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care adl

  • Subcutaneous Emphysema

    the presence of air or gas in subcutaneous tissue.

  • Subcutaneous Emphysema, CTCAE|Subcutaneous emphysema

    a disorder characterized by air in the subcutaneous tissue.

  • Traumatic Subcutaneous Emphysema

    the infiltration of air into the skin tissue secondary to traumatic tissue disruption.

  • Congenital Lobar Emphysema

    a rare abnormality in the lungs that is present at birth. it is characterized by hyperinflation of one or more lobes of the lungs. signs and symptoms appear early in life and include dyspnea, wheezing, and cyanosis.

Patient EducationClinical

Lung Diseases

When you breathe, your lungs take in oxygen from the air and deliver it to the bloodstream. The cells in your body need oxygen to work and grow. During a normal day, you breathe nearly 25,000 times. People with lung disease have difficulty breathing. Millions of people in the U.S. have lung disease.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert P25.0 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
770.2 NB interstit emphysema
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About P25.0Overview

Is P25.0 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report interstitial emphysema originating in the perinatal period on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What is the ICD-9 equivalent of P25.0?

Under the General Equivalence Mappings, interstitial emphysema originating in the perinatal period converts to ICD-9-CM 770.2 (NB interstit emphysema). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.