Other respiratory conditions originating in the perinatal period (P28) ICD-10-CM
The P28 code range covers other respiratory conditions originating in the perinatal period with 24 ICD-10-CM diagnosis codes. 19 of them are billable and valid for claim submission in fiscal year 2026, and the category headers group them but cannot themselves be billed.
Code Also
A "code also" note instructs that two codes may be required to fully describe a condition, but this note does not provide sequencing direction.
Codes in the P28 Range 24 codes · 19 billable
- P28 Other respiratory conditions originating in the perinatal periodNon-billable
- P28.0 Primary atelectasis of newborn
- P28.1 Other and unspecified atelectasis of newbornNon-billable
- P28.10 Unspecified atelectasis of newborn
- P28.11 Resorption atelectasis without respiratory distress syndrome
- P28.19 Other atelectasis of newborn
- P28.2 Cyanotic attacks of newborn
- P28.3 Primary sleep apnea of newbornNon-billable
- P28.30 Primary sleep apnea of newborn, unspecified
- P28.31 Primary central sleep apnea of newborn
- P28.32 Primary obstructive sleep apnea of newborn
- P28.33 Primary mixed sleep apnea of newborn
- P28.39 Other primary sleep apnea of newborn
- P28.4 Other apnea of newbornNon-billable
- P28.40 Unspecified apnea of newborn
- P28.41 Central neonatal apnea of newborn
- P28.42 Obstructive apnea of newborn
- P28.43 Mixed neonatal apnea of newborn
- P28.49 Other apnea of newborn
- P28.5 Respiratory failure of newborn
- P28.8 Other specified respiratory conditions of newbornNon-billable
- P28.81 Respiratory arrest of newborn
- P28.89 Other specified respiratory conditions of newborn
- P28.9 Respiratory condition of newborn, unspecified
Clinical Terms in This Code Range
Definitions from the National Library of Medicine for conditions coded in the P28 range.
Cyanosis
A bluish or purplish discoloration of the skin and mucous membranes due to an increase in the amount of deoxygenated hemoglobin in the blood or a structural defect in the hemoglobin molecule.
Hydrothorax
A collection of watery fluid in the pleural cavity. (Dorland, 27th ed)
Hypercapnia
A clinical manifestation of abnormal increase in the amount of carbon dioxide in arterial blood.
Middle Lobe Syndrome
Atelectasis of the right middle pulmonary lobe, with chronic pneumonitis. (Dorland, 27th ed)
Mouth Breathing
Abnormal breathing through the mouth, usually associated with obstructive disorders of the nasal passages.
Pleural Cavity
Paired but separate cavity within the THORACIC CAVITY. It consists of the space between the parietal and visceral PLEURA and normally contains a capillary layer of serous fluid that lubricates the pleural surfaces.
Pleural Effusion
Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. It is a sign of disease and not a diagnosis in itself.
Pleural Effusion, Malignant
Presence of fluid in the PLEURAL CAVITY as a complication of malignant disease. Malignant pleural effusions often contain actual malignant cells.
Xerostomia
Decreased salivary flow.
About the P28 Code Range
ICD-10 codes in the P28 category cover a range of respiratory conditions that originate in the perinatal period, focusing on newborns experiencing breathing difficulties such as atelectasis, apnea, cyanotic attacks, and respiratory failure. These codes uniquely identify specific neonatal respiratory issues for accurate clinical documentation and billing.
This section includes codes for various types of atelectasis like primary atelectasis of newborn (P28.0) and other forms including unspecified (P28.10) and resorption atelectasis (P28.11). Synonyms such as perinatal atelectasis and pulmonary hypoplasia associated with short gestation help clarify that these codes are used when lung collapse or incomplete lung expansion occurs in newborns. Additionally, codes for different apnea types—central, obstructive, and mixed (P28.31-P28.43)—are included with synonyms like infantile apnea and sleep apnea of newborn, guiding coders to distinguish primary sleep apnea from other apneas. The code for cyanotic attacks (P28.2) relates to episodes of newborn skin and mucous membrane cyanosis, sometimes referred to as blue baby syndrome. The section further covers respiratory failure (P28.5) and critical events like respiratory arrest (P28.81) in newborns. The unspecified codes (P28.9, P28.10, P28.40) allow documentation when detailed diagnosis is unavailable.
Using the ICD-10 code for respiratory conditions originating in the perinatal period ensures precise classification of neonatal respiratory disorders, facilitating appropriate care and reimbursement while distinguishing between diverse conditions like perinatal atelectasis, neonatal apnea, and respiratory failure.
Questions About This Page
How many billable codes are in the P28 range?
Of the 24 codes in this range, 19 are billable and valid for claim submission from October 1, 2025 through September 30, 2026. Category header codes group them but cannot be reported on claims.
What does the P28 range classify?
The range classifies other respiratory conditions originating in the perinatal period. Each code links to its own reference page with billing status, MS-DRG grouping, coding notes, and clinical information.
Related References
Source: CMS FY 2026 ICD-10-CM Tabular List and order file, effective October 1, 2025 through September 30, 2026.
