2026 ICD-10-CM Diagnosis Code P22.0Respiratory distress syndrome of newborn

ICD-10-CM CodesP00–P96P19-P29P22

ICD-10-CM P22.0
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

P22.0 is a billable ICD-10-CM diagnosis code for respiratory distress syndrome of newborn. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Respiratory distress syndrome.

Code Identity

ICD-10-CM Code
P22.0
Billable Status
Yes — Valid for Submission
Code Describes
Respiratory distress syndrome of newborn
Short Description
Respiratory distress syndrome of newborn
Same as the full description in the CMS dataset.
Parent Code
Respiratory distress of newborn

Code Classification

ChapterP00–P96Certain conditions originating in the perinatal period
SectionP19-P29Respiratory and cardiovascular disorders specific to the perinatal period
CategoryP22Respiratory distress of newborn
This CodeP22.0Respiratory distress syndrome of newborn

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Acute respiratory distress
  • Acute respiratory distress in newborn
  • Acute respiratory distress in newborn with surfactant disorder
  • Genetic disorder of surfactant dysfunction
  • Neonatal respiratory distress
  • Respiratory distress
  • Respiratory distress in early neonatal period
  • Respiratory distress syndrome in the newborn

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Cardiorespiratory distress syndrome of newborn
  • Hyaline membrane disease
  • Idiopathic respiratory distress syndrome IRDS or RDS of newborn
  • Pulmonary hypoperfusion syndrome
  • Respiratory distress syndrome, type I

Type 2 Excludes

  • respiratory arrest of newborn P28.81
  • respiratory failure of newborn NOS P28.5

Index to Diseases and InjuriesGuidance

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Disease, diseased
      • hyaline (diffuse) (generalized)
        • membrane (lung) (newborn)
    • Hyaline membrane(disease) (lung) (pulmonary) (newborn)
    • IRDS(type I)
    • RDS(newborn) (type I)
    • Respiratory
      • distress syndrome (newborn) (type I)
    • Syndrome
      • cardiorespiratory distress (idiopathic), newborn
    • Syndrome
      • idiopathic
        • cardiorespiratory distress, newborn
    • Syndrome
      • IRDS (idiopathic respiratory distress, newborn)
    • Syndrome
      • pulmonary
        • hypoperfusion (idiopathic)
    • Syndrome
      • RDS (respiratory distress syndrome, newborn)
    • Syndrome
      • respiratory
        • distress
          • newborn (idiopathic) (type I)

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR PNL005
Respiratory distress syndrome
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Lung Diseases

When you breathe, your lungs take in oxygen from the air and deliver it to the bloodstream. The cells in your body need oxygen to work and grow. During a normal day, you breathe nearly 25,000 times. People with lung disease have difficulty breathing. Millions of people in the U.S. have lung disease.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert P22.0 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
769 Respiratory distress syn
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About P22.0Overview

Is P22.0 (Respiratory distress of newborn) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report respiratory distress syndrome of newborn on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What is the ICD-9 equivalent of P22.0?

Under the General Equivalence Mappings, respiratory distress syndrome of newborn converts to ICD-9-CM 769 (respiratory distress syn). The mapping is a direct match.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.