2027 ICD-10-CM Diagnosis Code O01.0Classical hydatidiform mole

ICD-10-CM Codes›O00-O9A›O00-O08›O01

ICD-10-CM O01.0
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

O01.0 is a billable ICD-10-CM diagnosis code for classical hydatidiform mole. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 817 through 819, 831 through 833. The code is restricted by the Medicare Code Editor to maternity cases (age 9 through 64). Coders also document this condition as complete hydatidiform mole. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Molar pregnancy and other abnormal products of conception.

Code Identity

ICD-10-CM Code
O01.0
Billable Status
Yes — Valid for Submission
Code Describes
Classical hydatidiform mole
Short Description
Classical hydatidiform mole
Same as the full description in the CMS dataset.
Parent Code
Hydatidiform mole

Code Classification

ChapterO00-O9APregnancy, childbirth and the puerperium
SectionO00-O08Pregnancy with abortive outcome
CategoryO01Hydatidiform mole
This CodeO01.0Classical hydatidiform mole

Code EditsBilling

Medicare Code Editor checks that affect claim validity for O01.0.

The Medicare Code Editor detects inconsistencies in maternity cases by checking a patient's age and any diagnosis on the patient's record. The maternity code edits apply to patients age ange is 9–64 years inclusive (e.g., diabetes in pregnancy, antepartum pulmonary complication).

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Complete hydatidiform mole
  • Gestational trophoblastic disease
  • Hydatidiform mole, benign

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to O01.0: its own notes plus those printed at O01, block O00-O08, and Chapter 15. A note printed at a category, block or chapter applies to every code under it.

Applicable To

Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.

  • Complete hydatidiform mole

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From O01 Hydatidiform mole applies to 3 codes
  • chorioadenoma (destruens) (D39.2)
  • malignant hydatidiform mole (D39.2)
From Block O00-O08 Pregnancy with abortive outcome applies to 110 codes
  • continuing pregnancy in multiple gestation after abortion of one fetus or more (O31.1-, O31.3-)
From Chapter 15 (O00-O9A) Pregnancy, childbirth and the puerperium applies to 2,481 codes
  • supervision of normal pregnancy (Z34.-)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Chapter 15 (O00-O9A) Pregnancy, childbirth and the puerperium applies to 2,481 codes
  • mental and behavioral disorders associated with the puerperium (F53.-)
  • obstetrical tetanus (A34)
  • postpartum necrosis of pituitary gland (E23.0)
  • puerperal osteomalacia (M83.0)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

From O01 Hydatidiform mole applies to 3 codes
  • code from category O08 to identify any associated complication.
From Chapter 15 (O00-O9A) Pregnancy, childbirth and the puerperium applies to 2,481 codes
  • code, if applicable, from category Z3A, Weeks of gestation, to identify the specific week of the pregnancy, if known.

Notes

General instructions on how these codes are used.

From Chapter 15 (O00-O9A) Pregnancy, childbirth and the puerperium applies to 2,481 codes
  • CODES FROM THIS CHAPTER ARE FOR USE ONLY ON MATERNAL RECORDS, NEVER ON NEWBORN RECORDS
  • Codes from this chapter are for use for conditions related to or aggravated by the pregnancy, childbirth, or by the puerperium (maternal causes or obstetric causes)
  • Trimesters are counted from the first day of the last menstrual period. They are defined as follows:
  • 1st trimester- less than 14 weeks 0 days
  • 2nd trimester- 14 weeks 0 days to less than 28 weeks 0 days
  • 3rd trimester- 28 weeks 0 days until delivery

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name O01.0, its category, or a range that includes it.

Applicable To 1

These notes mention O01.0.

  • O08 Complications following ectopic and molar pregnancy
    This category is for use with categories O00-O02 to identify any associated complications names O00-O02, which includes this code

Excludes1 13

These codes carry an Excludes1 note naming O01.0: they are not reported together with it, unless the two conditions are unrelated.

  • O02.1 Missed abortion
    missed abortion with hydatidiform mole (O01.-) names O01.-, which includes this code
  • O02.8 Other specified abnormal products of conception
    abnormal products of conception with hydatidiform mole (O01.-) names O01.-, which includes this code
  • G08 Intracranial and intraspinal phlebitis and thrombophlebitis
    abortion, ectopic or molar pregnancy (O00-O07, O08.7) names O00-O07, which includes this code
  • K65 Peritonitis
    peritonitis with or following abortion or ectopic or molar pregnancy (O00-O07, O08.0) names O00-O07, which includes this code
  • Block N70-N77 Inflammatory diseases of female pelvic organs
    abortion or ectopic or molar pregnancy (O00-O07, O08.0) names O00-O07, which includes this code
  • R34 Anuria and oliguria
    anuria and oliguria complicating abortion or ectopic or molar pregnancy (O00-O07, O08.4) names O00-O07, which includes this code
  • R55 Syncope and collapse
    shock complicating or following abortion or ectopic or molar pregnancy (O00-O07, O08.3) names O00-O07, which includes this code
  • R57 Shock, not elsewhere classified
    shock complicating or following ectopic or molar pregnancy (O00-O07, O08.3) names O00-O07, which includes this code
  • T79.0 Air embolism (traumatic)
    air embolism complicating abortion or ectopic or molar pregnancy (O00-O07, O08.2) names O00-O07, which includes this code
  • T79.1 Fat embolism (traumatic)
    abortion or ectopic or molar pregnancy (O00-O07, O08.2) names O00-O07, which includes this code
  • T79.4 Traumatic shock
    shock complicating abortion or ectopic or molar pregnancy (O00-O07, O08.3) names O00-O07, which includes this code
  • T81.1 Postprocedural shock
    shock following abortion or ectopic or molar pregnancy (O00-O07, O08.3) names O00-O07, which includes this code
  • T81.7 Vascular complications following a procedure, not elsewhere classified
    embolism complicating abortion or ectopic or molar pregnancy (O00-O07, O08.2) names O00-O07, which includes this code

Excludes2 6

These codes carry an Excludes2 note naming O01.0: its condition is not part of those codes, and both may be reported when the patient has both.

  • D65 Disseminated intravascular coagulation [defibrination syndrome]
    abortion or ectopic or molar pregnancy (O00-O07, O08.1) names O00-O07, which includes this code
  • D68 Other coagulation defects
    coagulation defects complicating abortion or ectopic or molar pregnancy (O00-O07, O08.1) names O00-O07, which includes this code
  • I26 Pulmonary embolism
    pulmonary embolism complicating abortion, ectopic or molar pregnancy (O00-O07, O08.2) names O00-O07, which includes this code
  • K72 Hepatic failure, not elsewhere classified
    hepatic failure complicating abortion or ectopic or molar pregnancy (O00-O07, O08.8) names O00-O07, which includes this code
  • Block N17-N19 Acute kidney failure and chronic kidney disease
    renal failure complicating abortion or ectopic or molar pregnancy (O00-O07, O08.4) names O00-O07, which includes this code
  • Block N30-N39 Other diseases of the urinary system
    abortion or ectopic or molar pregnancy (O00-O07, O08.8) names O00-O07, which includes this code

Code First 6

These codes say to code first a condition named in the note, and O01.0 is one of the conditions named.

  • I47 Paroxysmal tachycardia
    abortion or ectopic or molar pregnancy (O00-O07, O08.8) names O00-O07, which includes this code
  • I49 Other cardiac arrhythmias
    abortion or ectopic or molar pregnancy (O00-O07, O08.8) names O00-O07, which includes this code
  • I50 Heart failure
    heart failure complicating abortion or ectopic or molar pregnancy (O00-O07, O08.8) names O00-O07, which includes this code
  • I74 Arterial embolism and thrombosis
    embolism and thrombosis complicating abortion or ectopic or molar pregnancy (O00-O07, O08.2) names O00-O07, which includes this code
  • I80 Phlebitis and thrombophlebitis
    if applicable: phlebitis and thrombophlebitis complicating abortion, ectopic or molar pregnancy (O00-O07, O08.7) names O00-O07, which includes this code
  • I82 Other venous embolism and thrombosis
    abortion, ectopic or molar pregnancy (O00-O07, O08.7) names O00-O07, which includes this code

Index to Diseases and InjuriesGuidance

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR PRG006
Molar pregnancy and other abnormal products of conception
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Complete Hydatidiform Mole

    a gestational trophoblastic disorder in which there is no embryo or normal placental tissue and the chorionic villi are hydropic.
  • Hydatidiform Mole

    trophoblastic hyperplasia associated with normal gestation, or molar pregnancy. it is characterized by the swelling of the chorionic villi and elevated human chorionic gonadotropin. hydatidiform moles or molar pregnancy may be categorized as complete or partial based on their gross morphology, histopathology, and karyotype.

Patient EducationClinical

Tumors and Pregnancy

Tumors during pregnancy are rare, but they can happen. Tumors can be either benign (not cancer) or malignant (cancer). The most common cancers in pregnancy include breast cancer, thyroid cancer, cervical cancer, lymphoma, and melanoma. Cancer itself rarely harms the fetus, and some cancer treatments are safe during pregnancy.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert O01.0 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
630 Hydatidiform mole
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About O01.0Overview

What is the ICD-10 code for classical hydatidiform mole?

The ICD-10-CM code for classical hydatidiform mole is O01.0 (sometimes written as O010). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is O01.0 (Hydatidiform mole) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report classical hydatidiform mole on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does O01.0 group to?

When classical hydatidiform mole is the principal diagnosis on an inpatient stay, it groups to MS-DRG 833, 832, 831, 819, 818, 817, with relative weights from 0.5000 to 1.7586 depending on complications. Higher weights mean higher Medicare reimbursement.

Who can O01.0 be reported for?

The Medicare Code Editor checks classical hydatidiform mole against patient demographics: this code is intended for maternity cases (age 9 through 64). Claims outside these limits are flagged as inconsistent.

Can O01.0 be reported with D39.2?

Not as a rule. The Excludes1 note at O01, which applies to O01.0, lists "chorioadenoma (destruens) (D39.2)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).