Hydatidiform mole (O01) ICD-10-CM
The O01 code range covers hydatidiform mole with 4 ICD-10-CM diagnosis codes. 3 of them are billable and valid for claim submission in fiscal year 2026, and the category headers group them but cannot themselves be billed.
Use Additional Code
The “use additional code” indicates that a secondary code could be used to further specify the patient’s condition. This note is not mandatory and is only used if enough information is available to assign an additional code.
- code from category O08
Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
Codes in the O01 Range 4 codes · 3 billable
Clinical Terms in This Code Range
Definitions from the National Library of Medicine for conditions coded in the O01 range.
Gestational Trophoblastic Disease
A group of diseases arising from pregnancy that are commonly associated with hyperplasia of trophoblasts (TROPHOBLAST) and markedly elevated human CHORIONIC GONADOTROPIN. They include HYDATIDIFORM MOLE, invasive mole (HYDATIDIFORM MOLE, INVASIVE), placental-site trophoblastic tumor (TROPHOBLASTIC TUMOR, PLACENTAL SITE), and CHORIOCARCINOMA. These neoplasms have varying propensities for invasion and spread.
Hydatidiform Mole
Trophoblastic hyperplasia associated with normal gestation, or molar pregnancy. It is characterized by the swelling of the CHORIONIC VILLI and elevated human CHORIONIC GONADOTROPIN. Hydatidiform moles or molar pregnancy may be categorized as complete or partial based on their gross morphology, histopathology, and karyotype.
Hydatidiform Mole, Invasive
A uterine tumor derived from persistent gestational TROPHOBLASTS, most likely after a molar pregnancy (HYDATIDIFORM MOLE). Invasive hyadatiform mole develops in about 15% of patients after evacuation of a complete mole and less frequently after other types of gestation. It may perforate the MYOMETRIUM and erode uterine vessels causing hemorrhage.
About the O01 Code Range
ICD-10 code O01 covers various forms of hydatidiform mole, a type of molar pregnancy characterized by abnormal growth of placental tissue. This code is essential for accurately identifying and classifying these abnormal gestational conditions.
The code O01 includes three main categories: O01.0 for classical or complete hydatidiform mole, O01.1 for incomplete or partial hydatidiform mole, and O01.9 for unspecified types. Conditions such as complete hydatidiform mole and partial hydatidiform mole fall under gestational trophoblastic disease, which is critical to recognize in clinical documentation. The unspecified category O01.9 also relates to rare but important complications like hyperthyroidism caused by molar tissue. Using these specific ICD-10 codes helps healthcare providers and coders differentiate between benign molar pregnancies and their complex variants to ensure precise diagnosis, treatment, and reporting.
Questions About This Page
How many billable codes are in the O01 range?
Of the 4 codes in this range, 3 are billable and valid for claim submission from October 1, 2025 through September 30, 2026. Category header codes group them but cannot be reported on claims.
What does the O01 range classify?
The range classifies hydatidiform mole. Each code links to its own reference page with billing status, MS-DRG grouping, coding notes, and clinical information.
Related References
Source: CMS FY 2026 ICD-10-CM Tabular List and order file, effective October 1, 2025 through September 30, 2026.
