2027 ICD-10-CM Diagnosis Code O00.121Right interstitial ectopic pregnancy without intrauterine pregnancy

ICD-10-CM Codes›O00-O9A›O00-O08›O00

ICD-10-CM O00.121
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

O00.121 is a billable ICD-10-CM diagnosis code for right interstitial ectopic pregnancy without intrauterine pregnancy. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 817 through 819, 831 through 833. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 34 closely related codes. The code is restricted by the Medicare Code Editor to maternity cases (age 9 through 64).

Code Identity

ICD-10-CM Code
O00.121
Billable Status
Yes — Valid for Submission
Code Describes
Right interstitial ectopic pregnancy without intrauterine pregnancy
Short Description
Right interstit ectopic pregnancy without uterin pregnancy
Parent Code
Interstitial ectopic pregnancy without intrauterine pregnancy

Code Classification

ChapterO00-O9APregnancy, childbirth and the puerperium
SectionO00-O08Pregnancy with abortive outcome
CategoryO00Ectopic pregnancy
This CodeO00.121Right interstitial ectopic pregnancy without intrauterine pregnancy

Code EditsBilling

Medicare Code Editor checks that affect claim validity for O00.121.

The Medicare Code Editor detects inconsistencies in maternity cases by checking a patient's age and any diagnosis on the patient's record. The maternity code edits apply to patients age ange is 9–64 years inclusive (e.g., diabetes in pregnancy, antepartum pulmonary complication).

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to O00.121: its own notes plus those printed at O00, block O00-O08, and Chapter 15. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From O00 Ectopic pregnancy applies to 34 codes
  • ruptured ectopic pregnancy

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From Block O00-O08 Pregnancy with abortive outcome applies to 110 codes
  • continuing pregnancy in multiple gestation after abortion of one fetus or more (O31.1-, O31.3-)
From Chapter 15 (O00-O9A) Pregnancy, childbirth and the puerperium applies to 2,481 codes
  • supervision of normal pregnancy (Z34.-)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Chapter 15 (O00-O9A) Pregnancy, childbirth and the puerperium applies to 2,481 codes
  • mental and behavioral disorders associated with the puerperium (F53.-)
  • obstetrical tetanus (A34)
  • postpartum necrosis of pituitary gland (E23.0)
  • puerperal osteomalacia (M83.0)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

From O00 Ectopic pregnancy applies to 34 codes
  • code from category O08 to identify any associated complication
From Chapter 15 (O00-O9A) Pregnancy, childbirth and the puerperium applies to 2,481 codes
  • code, if applicable, from category Z3A, Weeks of gestation, to identify the specific week of the pregnancy, if known.

Notes

General instructions on how these codes are used.

From Chapter 15 (O00-O9A) Pregnancy, childbirth and the puerperium applies to 2,481 codes
  • CODES FROM THIS CHAPTER ARE FOR USE ONLY ON MATERNAL RECORDS, NEVER ON NEWBORN RECORDS
  • Codes from this chapter are for use for conditions related to or aggravated by the pregnancy, childbirth, or by the puerperium (maternal causes or obstetric causes)
  • Trimesters are counted from the first day of the last menstrual period. They are defined as follows:
  • 1st trimester- less than 14 weeks 0 days
  • 2nd trimester- 14 weeks 0 days to less than 28 weeks 0 days
  • 3rd trimester- 28 weeks 0 days until delivery

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name O00.121, its category, or a range that includes it.

Applicable To 1

These notes mention O00.121.

  • O08 Complications following ectopic and molar pregnancy
    This category is for use with categories O00-O02 to identify any associated complications names O00-O02, which includes this code

Excludes1 12

These codes carry an Excludes1 note naming O00.121: they are not reported together with it, unless the two conditions are unrelated.

  • N83.6 Hematosalpinx
    tubal pregnancy (O00.1-) names O00.1-, which includes this code
  • G08 Intracranial and intraspinal phlebitis and thrombophlebitis
    abortion, ectopic or molar pregnancy (O00-O07, O08.7) names O00-O07, which includes this code
  • K65 Peritonitis
    peritonitis with or following abortion or ectopic or molar pregnancy (O00-O07, O08.0) names O00-O07, which includes this code
  • Block N70-N77 Inflammatory diseases of female pelvic organs
    abortion or ectopic or molar pregnancy (O00-O07, O08.0) names O00-O07, which includes this code
  • R34 Anuria and oliguria
    anuria and oliguria complicating abortion or ectopic or molar pregnancy (O00-O07, O08.4) names O00-O07, which includes this code
  • R55 Syncope and collapse
    shock complicating or following abortion or ectopic or molar pregnancy (O00-O07, O08.3) names O00-O07, which includes this code
  • R57 Shock, not elsewhere classified
    shock complicating or following ectopic or molar pregnancy (O00-O07, O08.3) names O00-O07, which includes this code
  • T79.0 Air embolism (traumatic)
    air embolism complicating abortion or ectopic or molar pregnancy (O00-O07, O08.2) names O00-O07, which includes this code
  • T79.1 Fat embolism (traumatic)
    abortion or ectopic or molar pregnancy (O00-O07, O08.2) names O00-O07, which includes this code
  • T79.4 Traumatic shock
    shock complicating abortion or ectopic or molar pregnancy (O00-O07, O08.3) names O00-O07, which includes this code
  • T81.1 Postprocedural shock
    shock following abortion or ectopic or molar pregnancy (O00-O07, O08.3) names O00-O07, which includes this code
  • T81.7 Vascular complications following a procedure, not elsewhere classified
    embolism complicating abortion or ectopic or molar pregnancy (O00-O07, O08.2) names O00-O07, which includes this code

Excludes2 6

These codes carry an Excludes2 note naming O00.121: its condition is not part of those codes, and both may be reported when the patient has both.

  • D65 Disseminated intravascular coagulation [defibrination syndrome]
    abortion or ectopic or molar pregnancy (O00-O07, O08.1) names O00-O07, which includes this code
  • D68 Other coagulation defects
    coagulation defects complicating abortion or ectopic or molar pregnancy (O00-O07, O08.1) names O00-O07, which includes this code
  • I26 Pulmonary embolism
    pulmonary embolism complicating abortion, ectopic or molar pregnancy (O00-O07, O08.2) names O00-O07, which includes this code
  • K72 Hepatic failure, not elsewhere classified
    hepatic failure complicating abortion or ectopic or molar pregnancy (O00-O07, O08.8) names O00-O07, which includes this code
  • Block N17-N19 Acute kidney failure and chronic kidney disease
    renal failure complicating abortion or ectopic or molar pregnancy (O00-O07, O08.4) names O00-O07, which includes this code
  • Block N30-N39 Other diseases of the urinary system
    abortion or ectopic or molar pregnancy (O00-O07, O08.8) names O00-O07, which includes this code

Code First 6

These codes say to code first a condition named in the note, and O00.121 is one of the conditions named.

  • I47 Paroxysmal tachycardia
    abortion or ectopic or molar pregnancy (O00-O07, O08.8) names O00-O07, which includes this code
  • I49 Other cardiac arrhythmias
    abortion or ectopic or molar pregnancy (O00-O07, O08.8) names O00-O07, which includes this code
  • I50 Heart failure
    heart failure complicating abortion or ectopic or molar pregnancy (O00-O07, O08.8) names O00-O07, which includes this code
  • I74 Arterial embolism and thrombosis
    embolism and thrombosis complicating abortion or ectopic or molar pregnancy (O00-O07, O08.2) names O00-O07, which includes this code
  • I80 Phlebitis and thrombophlebitis
    if applicable: phlebitis and thrombophlebitis complicating abortion, ectopic or molar pregnancy (O00-O07, O08.7) names O00-O07, which includes this code
  • I82 Other venous embolism and thrombosis
    abortion, ectopic or molar pregnancy (O00-O07, O08.7) names O00-O07, which includes this code

Clinical InformationClinical

  • Pregnancy, Tubal

    the most common (>96%) type of ectopic pregnancy in which the extrauterine embryo implantation occurs in the fallopian tube, usually in the ampullary region where fertilization takes place.

Code History & ChangesHistory

New Code O00.121 was added to the ICD-10-CM code set for FY 2027, effective October 1, 2026.

Replacement O00.121 replaces the following previously assigned code(s):

  • O00.101 - Right tubal pregnancy without intrauterine pregnancy
FY 2027AddedAdded to the ICD-10-CM code setEffective October 1, 2026.
FY 2027CurrentRevised in the current code setEffective October 1, 2026 through September 30, 2027.

Questions About O00.121Overview

What is the ICD-10 code for right interstitial ectopic pregnancy without intrauterine pregnancy?

The ICD-10-CM code for right interstitial ectopic pregnancy without intrauterine pregnancy is O00.121 (sometimes written as O00121). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is O00.121 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report right interstitial ectopic pregnancy without intrauterine pregnancy on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does O00.121 group to?

When right interstitial ectopic pregnancy without intrauterine pregnancy is the principal diagnosis on an inpatient stay, it groups to MS-DRG 833, 832, 831, 819, 818, 817, with relative weights from 0.5000 to 1.7586 depending on complications. Higher weights mean higher Medicare reimbursement.

Is O00.121 a CC or MCC?

CMS lists O00.121 as a CC (complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 34 closely related codes in its exclusion list.

Who can O00.121 be reported for?

The Medicare Code Editor checks right interstitial ectopic pregnancy without intrauterine pregnancy against patient demographics: this code is intended for maternity cases (age 9 through 64). Claims outside these limits are flagged as inconsistent.