2026 ICD-10-CM Diagnosis Code N25.9Disorder resulting from impaired renal tubular function, unspecified

ICD-10-CM Codes›N00–N99›N25-N29›N25

ICD-10-CM N25.9
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

N25.9 is a billable ICD-10-CM diagnosis code for disorder resulting from impaired renal tubular function, unspecified. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 698 through 700. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified diseases of kidney and ureters.

Code Identity

ICD-10-CM Code
N25.9
Billable Status
Yes — Valid for Submission
Code Describes
Disorder resulting from impaired renal tubular function, unspecified
Short Description
Disorder rslt from impaired renal tubular function, unsp
Parent Code
N25
Disorders resulting from impaired renal tubular function

Code Classification

ChapterN00–N99Diseases of the genitourinary system
SectionN25-N29Other disorders of kidney and ureter
CategoryN25Disorders resulting from impaired renal tubular function
This CodeN25.9Disorder resulting from impaired renal tubular function, unspecified

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Abnormal renal function
  • Abnormal renal tubular function
  • Azotemia
  • Coenzyme Q10 deficiency
  • Encephalopathy, hypertrophic cardiomyopathy, renal tubular disease syndrome
  • Hypertrophic cardiomyopathy and renal tubular disease due to mitochondrial DNA mutation
  • Hypertrophic mitochondrial cardiomyopathy
  • Inherited renal tubule insufficiency with cholestatic jaundice
  • Mitochondrial DNA depletion syndrome encephalomyopathic form
  • Prerenal azotemia
  • Renal tubular defect
  • Renal tubular disorder
  • Renal tubulopathy with encephalopathy and liver failure syndrome
  • RRM2B-related mitochondrial DNA depletion syndrome, encephalomyopathic form with renal tubulopathy
  • Secondary hypertension due to renal tubular disorder
  • Specific renal tubule transport defect

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Disorder(of)
      • impaired renal tubular function
    • Disorder(of)
      • kidney
        • functional (tubular)
    • Disorder(of)
      • kidney
        • tubular function
    • Disorder(of)
      • renal function, impaired (tubular)
    • Disorder(of)
      • tubulo-renal function, impaired
    • Impaired, impairment(function)
      • kidney
        • disorder resulting from
    • Impaired, impairment(function)
      • renal (acute) (chronic)
        • disorder resulting from

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR GEN006
Other specified and unspecified diseases of kidney and ureters
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Azotemia

    a biochemical abnormality referring to an elevation of blood urea nitrogen and creatinine. azotemia can be produced by kidney diseases or other extrarenal disorders. when azotemia becomes associated with a constellation of clinical signs, it is termed uremia.

  • Coenzyme Q10 Deficiency

    a genetically heterogeneous condition, typically inherited in an autosomal recessive fashion, characterized by coenzyme q10 deficiency.

Patient EducationClinical

Kidney Diseases

You have two kidneys, each about the size of your fist. They are near the middle of your back, just below the rib cage. Inside each kidney there are about a million tiny structures called nephrons. They filter your blood. They remove wastes and extra water, which become urine. The urine flows through tubes called ureters.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert N25.9 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
588.9 Impaired renal funct NOS
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About N25.9Overview

Is N25.9 (Disorders resulting from impaired renal tubular function) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report disorder resulting from impaired renal tubular function, unspecified on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does N25.9 group to?

When disorder resulting from impaired renal tubular function, unspecified is the principal diagnosis on an inpatient stay, it groups to MS-DRG 698, 699, 700, with relative weights from 0.6899 to 1.6544 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of N25.9?

Under the General Equivalence Mappings, disorder resulting from impaired renal tubular function, unspecified converts to ICD-9-CM 588.9 (impaired renal funct NOS). The mapping is a direct match.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.