2026 ICD-10-CM Diagnosis Code N25.81Secondary hyperparathyroidism of renal origin
ICD-10-CM Codes›N00–N99›N25-N29›N25
- Billable — Valid for Submission
- Chronic Condition
N25.81 is a billable ICD-10-CM diagnosis code for secondary hyperparathyroidism of renal origin. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 698 through 700. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified diseases of kidney and ureters.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Calcifying panniculitis due to hyperparathyroidism
- Calcifying panniculitis due to hyperparathyroidism in renal disease
- Chronic kidney disease mineral and bone disorder
- Hyperparathyroidism due to end stage renal disease on dialysis
- Hyperparathyroidism due to renal insufficiency
- Renal osteodystrophy
- Sagliker syndrome
- Secondary hyperparathyroidism
- Subcutaneous calcification
Tabular List NotesGuidance
Coding notes and annotation back-references applicable to this code.
Type 1 Excludes
- secondary hyperparathyroidism, non-renal E21.1
Type 2 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
A type 2 excludes note represents "Not included here". An excludes2 note indicates that the condition excluded is not part of the condition represented by the code, but a patient may have both conditions at the same time. When an Excludes2 note appears under a code, it is acceptable to use both the code and the excluded code together, when appropriate.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
- secondary (renal) - N25.81
External Cause of Injuries IndexGuidance
References for this code in the External Cause of Injuries Index.
- Hyperparathyroidism
- secondary (renal)
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Secondary Hyperparathyroidism
overproduction of parathyroid hormone in response to influence external to the parathyroid glands.
Patient EducationClinical
Parathyroid Disorders
Most people have four pea-sized glands, called parathyroid glands, on the thyroid gland in the neck. Though their names are similar, the thyroid and parathyroid glands are completely different. The parathyroid glands make parathyroid hormone (PTH), which helps your body keep the right balance of calcium and phosphorous.
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert N25.81 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About N25.81Overview
Is N25.81 a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report secondary hyperparathyroidism of renal origin on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
What MS-DRG does N25.81 group to?
When secondary hyperparathyroidism of renal origin is the principal diagnosis on an inpatient stay, it groups to MS-DRG 698, 699, 700, with relative weights from 0.6899 to 1.6544 depending on complications. Higher weights mean higher Medicare reimbursement.
What is the ICD-9 equivalent of N25.81?
Under the General Equivalence Mappings, secondary hyperparathyroidism of renal origin converts to ICD-9-CM 588.81 (sec hyperparathyrd-renal). The mapping is a direct match.
Footnotes
[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:
- The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
- The condition places limitations on self-care, independent living, and social interactions.
