2026 ICD-10-CM Diagnosis Code M81.6Localized osteoporosis [Lequesne]

ICD-10-CM Codes›M00–M99›M80-M85›M81

ICD-10-CM M81.6
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

M81.6 is a billable ICD-10-CM diagnosis code for localized osteoporosis [Lequesne]. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 553 through 554. Coders also document this condition as localized osteoporosis - Lequesne. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Osteoporosis.

Code Identity

ICD-10-CM Code
M81.6
Billable Status
Yes — Valid for Submission
Code Describes
Localized osteoporosis [Lequesne]
Short Description
Localized osteoporosis [Lequesne]
Same as the full description in the CMS dataset.
Parent Code
M81
Osteoporosis without current pathological fracture

Code Classification

ChapterM00–M99Diseases of the musculoskeletal system and connective tissue
SectionM80-M85Disorders of bone density and structure
CategoryM81Osteoporosis without current pathological fracture
This CodeM81.6Localized osteoporosis [Lequesne]

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Localized osteoporosis - Lequesne
  • Secondary localized osteoporosis

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Type 1 Excludes

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Osteoporosis(female) (male)
      • Lequesne
    • Osteoporosis(female) (male)
      • localized

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR MUS013
Osteoporosis
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Osteoporosis

Osteoporosis is a disease in which your bones become weak and are likely to fracture (break). The disease can develop when your bone mineral density and bone mass decrease. It can also happen if the structure and strength of your bones change.

The full article covers:

  • What is osteoporosis?
  • What causes osteoporosis?
  • Who is more likely to develop osteoporosis?
  • What are the symptoms of osteoporosis?
  • How is osteoporosis diagnosed?
  • What are the treatments for osteoporosis?
  • Can osteoporosis be prevented?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert M81.6 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
733.09 Osteoporosis NEC
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About M81.6Overview

Is M81.6 (Osteoporosis without current pathological fracture) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report localized osteoporosis [Lequesne] on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does M81.6 group to?

When localized osteoporosis [Lequesne] is the principal diagnosis on an inpatient stay, it groups to MS-DRG 553, 554, with relative weights from 0.8301 to 1.2963 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of M81.6?

Under the General Equivalence Mappings, localized osteoporosis [Lequesne] converts to ICD-9-CM 733.09 (osteoporosis NEC). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.