2027 ICD-10-CM Diagnosis Code M46.31Infection of intervertebral disc (pyogenic), occipito-atlanto-axial region

ICD-10-CM Codes›M00–M99›M45-M49›M46

ICD-10-CM M46.31
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

M46.31 is a billable ICD-10-CM diagnosis code for infection of intervertebral disc (pyogenic), occipito-atlanto-axial region. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 456 through 458, 539 through 541. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 221 closely related codes. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Spondylopathies/spondyloarthropathy (including infective).

For Medicare Advantage risk adjustment, M46.31 maps to CMS-HCC Category 92 (Bone/Joint/Muscle/Severe Soft Tissue Infections/Necrosis) under the V28 model, adding a risk factor of about 0.479 for a community, non-dual, aged beneficiary in payment year 2027.

Code Identity

ICD-10-CM Code
M46.31
Billable Status
Yes — Valid for Submission
Code Describes
Infection of intervertebral disc (pyogenic), occipito-atlanto-axial region
Short Description
Infection of intvrt disc (pyogenic), occipt-atlan-ax region
Parent Code
Infection of intervertebral disc (pyogenic)

Code Classification

ChapterM00–M99Diseases of the musculoskeletal system and connective tissue
SectionM45-M49Spondylopathies
CategoryM46Other inflammatory spondylopathies
This CodeM46.31Infection of intervertebral disc (pyogenic), occipito-atlanto-axial region

Medicare Risk Adjustment (HCC)Billing

M46.31 maps to a payment category in the CMS-HCC model used to risk-adjust Medicare Advantage payments. Weights are the published community factors for payment year 2027.

CMS-HCC V28 Category (Payment Model)
HCC 92— Bone/Joint/Muscle/Severe Soft Tissue Infections/Necrosis
Payment HCC · PY 2027 one of 609 ICD-10-CM codes in this category
Risk Adjustment Factor (RAF) Weight
+0.479
community, non-dual, aged · ranges 0.471–0.632 across segments
Hierarchy
Top of its hierarchy
HCC 92 is not superseded by any other condition category
Prior Model (CMS-HCC V24)
HCC 39
V24 retired V28 pays 100% of MA risk scores since PY 2026
Other CMS Models
PACE (CMS-HCC V22): HCC 39 · ESRD (V21): HCC 39 · ESRD (V24): HCC 39
ESRD V21 weights: 0.061 dialysis, 0.375–0.468 functioning graft · ESRD V24 weights: 0.092 dialysis, 0.431–0.578 functioning graft
Part D (RxHCC)
Not mapped
M46.31 does not risk-adjust in the RxHCC prescription drug model

Source: CMS Payment Year 2027 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to M46.31: its own notes plus those printed at M46.3 and Chapter 13. A note printed at a category, block or chapter applies to every code under it.

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Chapter 13 (M00-M99) Diseases of the musculoskeletal system and connective tissue applies to 6,687 codes
  • arthropathic psoriasis (L40.5-)
  • certain conditions originating in the perinatal period (P04-P96)
  • certain infectious and parasitic diseases (A00-B99)
  • compartment syndrome (traumatic) (T79.A-)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

From M46.3 Infection of intervertebral disc (pyogenic) applies to 10 codes
  • code (B95-B97) to identify infectious agent.

Notes

General instructions on how these codes are used.

From Chapter 13 (M00-M99) Diseases of the musculoskeletal system and connective tissue applies to 6,687 codes
  • Use an external cause code following the code for the musculoskeletal condition, if applicable, to identify the cause of the musculoskeletal condition

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name M46.31, its category, or a range that includes it.

Excludes1 1

These codes carry an Excludes1 note naming M46.31: they are not reported together with it, unless the two conditions are unrelated.

  • G55 Nerve root and plexus compressions in diseases classified elsewhere
    nerve root compression (due to) (in) spondylopathies (M46.-, M48.-) names M46.-, which includes this code

Index to Diseases and InjuriesGuidance

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR MUS011
Spondylopathies/spondyloarthropathy (including infective)
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Spine Injuries and Disorders

Your backbone, or spine, is made up of 26 bone discs called vertebrae. The vertebrae protect your spinal cord and allow you to stand and bend. A number of problems can change the structure of the spine or damage the vertebrae and surrounding tissue. They include:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert M46.31 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
730.98 Bone infect NOS-oth site
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About M46.31Overview

Is M46.31 (Infection of intervertebral disc (pyogenic)) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report infection of intervertebral disc (pyogenic), occipito-atlanto-axial region on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does M46.31 group to?

When infection of intervertebral disc (pyogenic), occipito-atlanto-axial region is the principal diagnosis on an inpatient stay, it groups to MS-DRG 541, 456, 457, 539, 540, 458, with relative weights from 0.8293 to 7.6211 depending on complications. Higher weights mean higher Medicare reimbursement.

Is M46.31 a CC or MCC?

CMS lists M46.31 as a CC (complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 221 closely related codes in its exclusion list.

Does M46.31 need an additional code?

When the condition applies, yes. The Use Additional Code note at M46.3, which applies to M46.31, reads: code (B95-B97) to identify infectious agent.. The additional code is reported after M46.31.

What is the ICD-9 equivalent of M46.31?

Under the General Equivalence Mappings, infection of intervertebral disc (pyogenic), occipito-atlanto-axial region converts to ICD-9-CM 730.98 (bone infect NOS-oth site). The mapping is approximate, so confirm the match fits the documentation.

What HCC is M46.31?

M46.31 (infection of intervertebral disc (pyogenic), occipito-atlanto-axial region) maps to CMS-HCC Category 92 (Bone/Joint/Muscle/Severe Soft Tissue Infections/Necrosis), commonly written as HCC 92, in the CMS-HCC V28 model used for Medicare Advantage risk adjustment in payment year 2027. It mapped to HCC 39 under the retired V24 model. It also maps in the PACE (CMS-HCC V22), ESRD (V21), and ESRD (V24) models. It does not map to any RxHCC in the Part D prescription drug model.

Does M46.31 risk-adjust for Medicare Advantage payment?

Yes. When documented and reported on a Medicare Advantage encounter, M46.31 adds a risk adjustment factor of about 0.479 to the beneficiary's RAF score for a community, non-dual, aged enrollee (published V28 weights range from 0.471 to 0.632 depending on the payment segment). HCC 92 sits at the top of its hierarchy, so no other condition category supersedes it. See the full factor table on the HCC 92 category page.