2027 ICD-10-CM Diagnosis Code L81.6Other disorders of diminished melanin formation
ICD-10-CM Codes›L00–L99›L80-L99›L81
- Billable — Valid for Submission
- Not Chronic
L81.6 is a billable ICD-10-CM diagnosis code for other disorders of diminished melanin formation. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 606 through 607, 795. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified skin disorders.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Achromia of skin
- Acquired hypomelanosis of uncertain etiology
- Acquired hypomelanotic disorder
- Acquired poikiloderma
- Alezzandrini syndrome
- Chemically-induced hypomelanosis
- Circumscribed hypomelanosis
- Complication due to and following cosmetic surgery
- Complication of cryotherapy procedure
- Complication of laser surgery
- Disorder of pigmentation of skin following cosmetic surgery
- Disorder of skin due to radiotherapy
- Drug-induced hypomelanosis
- Hereditary acrokeratotic poikiloderma of Weary
- Hereditary fibrosing poikiloderma, tendon contractures, myopathy, pulmonary fibrosis syndrome
- Hereditary sclerosing poikiloderma
- Hypomelanosis due to cryotherapy
- Hypomelanosis due to scarring
- Hypomelanosis of skin as a complication of cosmetic procedure
- Hypomelanosis surrounding malignant melanoma
- Hypomelanosis surrounding melanocytic neoplasm
- Hypomelanotic mycosis fungoides
- Hypomelanotic sarcoidosis
- Laser-induced dyspigmentation
- Laser-induced hypopigmentation
- Localized hereditary amyloidosis
- Macule of skin
- Neoplastic sequelae of disorders
- Onchocercal depigmentation
- Onchodermatitis
- Poikiloderma
- Poikiloderma caused by cold injury
- Poikiloderma caused by ionizing radiation
- Poikiloderma caused by photodynamic agent
- Poikiloderma due to and following radiotherapy
- Poikiloderma due to connective tissue disease
- Poikiloderma due to heat of infrared radiation therapy
- Poikiloderma due to lichen planus
- Poikiloderma due to lupus erythematosus
- Poikiloderma due to scleroderma
- Poikiloderma with neutropenia
- Poikilodermal cutaneous amyloid
- Poikilodermatous mycosis fungoides
- Post-infective hypomelanosis
- Post-inflammatory hypopigmentation
- Postinflammatory skin pigmentation change
- Progressive macular hypomelanosis
- Symmetrical progressive leucopathy
- Tendon contracture
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to L81.6: its own notes plus those printed at L81 and Chapter 12. A note printed at a category, block or chapter applies to every code under it.
Excludes1
Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
- nevus - see Alphabetical Index
- certain conditions originating in the perinatal period (P04-P96)
- certain infectious and parasitic diseases (A00-B99)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- lipomelanotic reticulosis (I89.8)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
- systemic connective tissue disorders (M30-M36)
- viral warts (B07.-)
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Disorder (of) See Also: Disease;
Poikiloderma L81.6
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Patient EducationClinical
Skin Pigmentation Disorders
Pigmentation means coloring. Skin pigmentation disorders affect the color of your skin. Your skin gets its color from a pigment called melanin. Special cells in the skin make melanin. When these cells become damaged or unhealthy, it affects melanin production. Some pigmentation disorders affect just patches of skin.
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert L81.6 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About L81.6Overview
What is the ICD-10 code for other disorders of diminished melanin formation?
The ICD-10-CM code for other disorders of diminished melanin formation is L81.6 (sometimes written as L816). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is L81.6 (Other disorders of pigmentation) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report other disorders of diminished melanin formation on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does L81.6 group to?
When other disorders of diminished melanin formation is the principal diagnosis on an inpatient stay, it groups to MS-DRG 795, 607, 606, with relative weights from 0.2022 to 1.5721 depending on complications. Higher weights mean higher Medicare reimbursement.
Can L81.6 be reported with Q82.5?
Not as a rule. The Excludes1 note at L81, which applies to L81.6, lists "birthmark NOS (Q82.5)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).
What is the ICD-9 equivalent of L81.6?
Under the General Equivalence Mappings, other disorders of diminished melanin formation converts to ICD-9-CM 709.09 (other dyschromia). The mapping is approximate, so confirm the match fits the documentation.
