L85.0 - Acquired ichthyosis

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

• Acquired ichthyosis
• Chapped skin
• Desiccation eczema
• Senile ichthyosis
• Senile xeroderma
• Xeroderma

Clinical Information

• DDB2 wt Allele|DDB P48 Subunit Gene|DDBB|Damage-Specific DNA Binding Protein 2, 48kDa wt Allele|FLJ34321|UV-DDB2|UV-Damaged DNA-Binding Protein 2 Gene|XPE|Xeroderma Pigmentosum Group E Protein Gene-. human ddb2 wild-type allele is located within 11p12-p11 and is approximately 24 kb in length. this allele, which encodes dna damage-binding protein 2, is involved in dna repair. mutation of the gene is associated with xeroderma pigmentosum complementation group e.
• Deleterious ERCC3 Gene Mutation|Deleterious BTF2 Gene Mutation|Deleterious ERCC Excision Repair 3, TFIIH Core Complex Helicase Subunit Gene Mutation|Deleterious Excision Repair Cross-Complementation Group 3 Gene Mutation|Deleterious Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 3 Gene Mutation|Deleterious Excision-Repair, Complementing Defective, in Chinese Hamster, 3 Gene Mutation|Deleterious GTF2H Gene Mutation|Deleterious RAD25 Gene Mutation|Deleterious TTD2 Gene Mutation|Deleterious XPB Gene Mutation|Deleterious Xeroderma Pigmentosum Group B Complementing Gene Mutation-. a change in the nucleotide sequence of the ercc3 gene that is associated with increased risk of disease.
• DNA Damage-Binding Protein 1|DDB p127 Subunit|DDB1|DDBa|DNA Damage-Binding Protein a|Damage-Specific DNA-Binding Protein 1|HBV X-Associated Protein 1|UV-DDB 1|UV-Damaged DNA-Binding Factor|UV-Damaged DNA-Binding Protein 1|XAP-1|XPE-BF|XPE-Binding Factor|Xeroderma Pigmentosum Group E-Complementing Protein-. dna damage-binding protein 1 (1140 aa, ~127 kda) is encoded by the human ddb1 gene. this protein is involved in both protein ubiquitination and dna damage repair.
• DNA Polymerase Eta|EC 2.7.7.7|POLH|RAD30 Homolog A|Xeroderma Pigmentosum Variant Type Protein-. dna polymerase eta (713 aa, ~78 kda) is encoded by the human polh gene. this protein plays a role in repair of uv-induced pyrimidine dimers in dna.
• DNA Repair Endonuclease XPF|DNA Excision Repair Protein ERCC-4|DNA Repair Protein Complementing XP-F Cells|EC 3.1.-.|ERCC4|RAD1|XPF|Xeroderma Pigmentosum Group F-Complementing Protein|Xeroderma Pigmentosum, Complementation Group F-. dna repair endonuclease xpf (916 aa, ~104 kda) is encoded by the human ercc4 gene. this protein is involved in dna double strand break and nucleotide excision repair.
• DNA Repair Protein Complementing XP-A Cells|XPA|Xeroderma Pigmentosum Complementation Group A Protein|Xeroderma Pigmentosum Group A Complementing Protein|Xeroderma Pigmentosum Group A-Complementing Protein-. dna repair protein complementing xp-a cells (273 aa, ~31 kda) is encoded by the human xpa gene. this protein is involved in dna excision repair.
• DNA Repair Protein Complementing XP-C Cells|XPC|Xeroderma Pigmentosum Group C Protein|Xeroderma Pigmentosum Group C-Complementing Protein|p125-. dna repair protein complementing xp-c cells (940 aa, ~106 kda) is encoded by the human xpc gene. this protein is involved in the mediation of dna repair.
• DNA Repair Protein Complementing XP-G Cells|DNA Excision Repair Protein ERCC-5|EC 3.1.-.-|ERCC5|ERCM2|UVDR|XPG|XPG-Complementing Protein|XPGC|Xeroderma Pigmentosum Group G Complementing Protein|Xeroderma Pigmentosum Group G-Complementing Protein|Xeroderma Pigmentosum, Complementation Group G|Xeroderma Pigmentosum, Group G Correcting Protein-. dna repair protein complementing xp-g cells (1186 aa, ~133 kda) is encoded by the human ercc5 gene. this protein plays a role in the repair of uv-induced dna damage.
• ERCC2 NP_000391.1:p.F332V|BTF2 p80 F332V|BTF2 p80 Phe332Val|Basic Transcription Factor 2 80 kDa Subunit F332V|Basic Transcription Factor 2 80 kDa Subunit Phe332Val|CXPD F332V|CXPD Phe332Val|DNA Excision Repair Protein ERCC-2 F332V|DNA Excision Repair Protein ERCC-2 Phe332Val|DNA Repair Protein Complementing XP-D Cells F332V|DNA Repair Protein Complementing XP-D Cells Phe332Val|DNA-Repair Protein XPD F332V|DNA-Repair Protein XPD Phe332Val|ERCC2 F332V|ERCC2 NP_000391.1:p.Phe322Val|ERCC2 Phe322Val|ERCC2 p.F322V|ERCC2 p.Phe322Val|General Transcription and DNA Repair Factor IIH Helicase Subunit XPD F332V|General Transcription and DNA Repair Factor IIH Helicase Subunit XPD Phe332Val|NP_000391.1:p.F332V|NP_000391.1:p.Phe322Val|TFIIH 80 kDa Subunit F332V|TFIIH 80 kDa Subunit Phe332Val|TFIIH Basal Transcription Factor Complex 80 kDa Subunit F332V|TFIIH Basal Transcription Factor Complex 80 kDa Subunit Phe332Val|TFIIH Basal Transcription Factor Complex Helicase XPD Subunit F332V|TFIIH Basal Transcription Factor Complex Helicase XPD Subunit Phe332Val|TFIIH p80 F332V|TFIIH p80 Phe332Val|TFIIH subunit XPD F332V|TFIIH subunit XPD Phe332Val|Xeroderma Pigmentosum Group D-Complementing Protein F332V|Xeroderma Pigmentosum Group D-Complementing Protein Phe332Val-. a change in the amino acid residue at position 332 in the general transcription and dna repair factor iih helicase subunit xpd protein where phenylalanine has been replaced by valine.
• ERCC2 Protein Variant|BTF2 p80 Protein Variant|Basic Transcription Factor 2 80 kDa Subunit Protein Variant|CXPD Protein Variant|DNA Excision Repair Protein ERCC-2 Protein Variant|DNA Repair Protein Complementing XP-D Cells Protein Variant|DNA-Repair Protein XPD Protein Variant|General Transcription and DNA Repair Factor IIH Helicase Subunit XPD Protein Variant|TFIIH 80 kDa Subunit Protein Variant|TFIIH Basal Transcription Factor Complex 80 kDa Subunit Protein Variant|TFIIH Basal Transcription Factor Complex Helicase XPD Subunit Protein Variant|TFIIH Subunit XPD Protein Variant|TFIIH p80 Protein Variant|Xeroderma Pigmentosum Group D-Complementing Protein Protein Variant-. a variation in the amino acid sequence for the general transcription and dna repair factor iih helicase subunit xpd protein.
• ERCC2 wt Allele|COFS2|CXPD|DNA Repair Defect EM9 of Chinese Hamster Ovary Cells, Complementation of Gene|EM9|ERCC Excision Repair 2, TFIIH Core Complex Helicase Subunit wt Allele|ERCC2|Excision Repair Cross-Complementation Group 2 Gene|Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2 (Xeroderma Pigmentosum D) Gene|Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2 Gene|Excision-Repair, Complementing Defective, In Chinese Hamster, 2 Gene|MAG|MGC102762|MGC126218|MGC126219|TTD|TTD1|XP, Group D|XP4|XPD|XPD Gene|XPDC|Xeroderma Pigmentosum Complementary Group D Gene-. human ercc2 wild-type allele is located in the vicinity of 19q13.3 and is approximately 19 kb in length. this allele, which encodes general transcription and dna repair factor iih helicase subunit xpd protein, is involved in transcription-coupled nucleotide excision repair. defects in this allele can result in three different disorders, xeroderma pigmentosum complementation group d, trichothiodystrophy and cockayne syndrome.
• ERCC3 Gene Mutation|BTF2 Gene Mutation|ERCC Excision Repair 3, TFIIH Core Complex Helicase Subunit Gene Mutation|Excision Repair Cross-Complementation Group 3 Gene Mutation|Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 3 Gene Mutation|Excision-Repair, Complementing Defective, in Chinese Hamster, 3 Gene Mutation|GTF2H Gene Mutation|RAD25 Gene Mutation|TTD2 Gene Mutation|XPB Gene Mutation|Xeroderma Pigmentosum Group B Complementing Gene Mutation-. a change in the nucleotide sequence of the ercc3 gene.
• ERCC3 wt Allele|BTF2|BTF2-p89 Gene|Basic Transcription Factor 2 89 kDa Subunit Gene|ERCC Excision Repair 3, TFIIH Core Complex Helicase Subunit wt Allele|Excision Repair Cross-Complementation Group 3 Gene|Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 3 (Xeroderma Pigmentosum Group B Complementing) Gene|Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 3 Gene|Excision-Repair, Complementing Defective, In Chinese Hamster, 3 Gene|Excision-Repair, Complementing Defective, in Chinese Hamster, 3 Gene|GTF2H|RAD25|TFIIH|TFIIH 89 kDa Subunit Gene|TFIIH Basal Transcription Factor Complex Helicase XPB Subunit Gene|XPB|XPBC|Xeroderma Pigmentosum Group B Complementing Gene-. human ercc3 wild-type allele is located within 2q21 and is approximately 37 kb in length. this allele, which encodes tfiih basal transcription factor complex helicase xpb subunit protein, plays a role in nucleotide excision repair and transcription.
• ERCC5 wt Allele|COFS3|Cockayne Syndrome Gene|ERCC Excision Repair 5, Endonuclease wt Allele|ERCM2|ERCM2 Gene|Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 5 (Xeroderma Pigmentosum, Complementation Group G (Cockayne syndrome)) Gene|Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 5 Gene|Excision-Repair, Complementing Defective, In Chinese Hamster, 5 Gene|RAD2, Yeast, Homolog of Gene|UV Damage, Excision Repair of, UV-135 Gene|UVDR|UVDR Gene|XPG|XPG Gene|XPGC|XPGC Gene-. human ercc5 wild-type allele is located in the vicinity of 13q33.1 and is approximately 30 kb in length. this allele, which encodes dna-repair protein complementing xp-g cells protein, is involved in the transcription-coupled repair of ultraviolet-induced dna damage.
• General Transcription and DNA Repair Factor IIH Helicase Subunit XPD|BTF2 p80|Basic Transcription Factor 2 80 kDa Subunit|CXPD|DNA Excision Repair Protein ERCC-2|DNA Repair Protein Complementing XP-D Cells|DNA-Repair Protein Complementing XP-D Cells|DNA-Repair Protein XPD|EC 3.6.1.-|ERCC2|Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2 Protein|TFIIH 80 kDa Subunit|TFIIH Basal Transcription Factor Complex 80 kDa Subunit|TFIIH Basal Transcription Factor Complex Helicase XPD Subunit|TFIIH Basal Transcription Factor Complex Helicase XPD Subunit|TFIIH P80|TFIIH p80|Xeroderma Pigmentosum Group D Complementing Protein|Xeroderma Pigmentosum Group D-Complementing Protein-. general transcription and dna repair factor iih helicase subunit xpd (760 aa, ~87 kda) is encoded by the human ercc2 gene. this protein plays a role in dna helicase activity, rna polymerase ii-mediated transcription and nucleotide excision repair.
• Inactivating ERCC3 Gene Mutation|ERCC3 Gene Inactivation|ERCC3 Inactivating Gene Mutation|ERCC3 Inactivating Mutation|ERCC3 Loss of Function Gene Mutation|ERCC3 Loss of Function Mutation|Inactivating BTF2 Gene Mutation|Inactivating ERCC Excision Repair 3, TFIIH Core Complex Helicase Subunit Gene Mutation|Inactivating ERCC3 Mutation|Inactivating Excision Repair Cross-Complementation Group 3 Gene Mutation|Inactivating Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 3 Gene Mutation|Inactivating Excision-Repair, Complementing Defective, in Chinese Hamster, 3 Gene Mutation|Inactivating GTF2H Gene Mutation|Inactivating RAD25 Gene Mutation|Inactivating TTD2 Gene Mutation|Inactivating XPB Gene Mutation|Inactivating Xeroderma Pigmentosum Group B Complementing Gene Mutation-. a change in the nucleotide sequence of the ercc3 gene that either inhibits expression or results in the translation of an inactive tfiih basal transcription factor complex helicase xpb subunit protein.
• TFIIH Basal Transcription Factor Complex Helicase XPB Subunit|BTF2 p89|BTF2-p89|Basic Transcription Factor 2 89 kDa Subunit|DNA Excision Repair Protein ERCC-3|DNA Repair Protein Complementing XP-B Cells|DNA-Repair Protein Complementing XP-B Cells|EC 3.6.4.12|ERCC3|TFIIH 89 kDa Subunit|TFIIH Basal Transcription Factor Complex 89 kDa Subunit|TFIIH p89|Xeroderma Pigmentosum Group B Complementing Protein|Xeroderma Pigmentosum Group B-Complementing Protein-. tfiih basal transcription factor complex helicase xpb subunit (782 aa, ~89 kda) is encoded by the human ercc3 gene. this protein is involved in rna polymerase ii-mediated transcription, dna helicase activity and nucleotide excision repair.
• Xeroderma-. a non-neoplastic disorder characterized by abnormally dry skin. causes include vitamin a deficiency, sunlight exposure, medications, metabolic disorders, autoimmune disorders, and hereditary genetic disorders.
• Xeroderma Pigmentosum Variant Type|XPV-. a type of xeroderma pigmentosum resulting from mutation(s) in the polh gene, encoding dna polymerase eta. this form of the disease is characterized by normal dna excision repair, but defective post-replication repair of dna at uv-damaged sites.
• Xeroderma Pigmentosum, Complementation Group C|XP-C|Xeroderma Pigmentosum Group C-. an autosomal recessive inherited disorder caused by mutations in the xpc gene. this disease is characterized by increased sensitivity to sunlight with the development of carcinomas at an early age and is caused by a defect in nucleotide excision repair.
• Xeroderma Pigmentosum, Complementation Group E|XP-E|Xeroderma Pigmentosum Group E-. an autosomal recessive genetic disorder caused by mutations in the ddb2 gene. this disease exhibits the mildest degree of sun sensitivity of all xeroderma pigmentosum complementation groups, although individuals are at high risk for skin cancer.
• Xeroderma Pigmentosum|Angioma Pigmentosum Atrophicum|Atrophoderma Pigmentosum|Kaposi Dermatosis|Kaposi Disease|Melanosis Lenticularis Progressiva|Pigmented Epitheliomatosis|Xeroderma Pigmentosum Syndrome|Xeroderma of Kaposi|xeroderma pigmentosum-. an inherited skin disorder characterized by photosensitivity with severe sunburn in infancy, the development of numerous pigmented spots resembling freckles, larger atrophic lesions associated with telangiectasis, and multiple solar keratoses. transmitted in an autosomal recessive manner, xeroderma pigmentosa involves a defect in nucleotide excision repair (ner), leading to deficient repair of dna damaged by uv radiation and chromosome breakage. individuals with this disease develop multiple malignant cutaneous neoplasms at an early age and may suffer from severe ophthalmic and neurologic abnormalities.
• Xeroderma Pigmentosum-Cockayne Syndrome Complex|XP-CS|XP/CS|Xeroderma Pigmentosum/Cockayne Syndrome-. a condition characterized by the cutaneous features of xeroderma pigmentosum and the systemic and neurological features of cockayne syndrome.
• XPA Gene|XPA|XPA|XPA|XPA|Xeroderma Pigmentosum, Complementation Group A Gene-. this gene facilitates dna binding in repair processes and is associated with the disease xeroderma pigmentosum complementation group a.
• XPA wt Allele|XP, Group A|XP, Group A Gene|XP1|XP1 Gene|XPA|XPA Complementing Gene|XPA Correcting Gene|XPAC|XPAC Gene|Xeroderma Pigmentosum I Gene|Xeroderma Pigmentosum, Complementation Group A wt Allele-. human xpa wild-type allele is located in the vicinity of 9q22.3 and is approximately 22 kb in length. this allele, which encodes dna-repair protein complementing xp-a cells protein, is involved in the dna excision repair pathway. defects in this pathway lead to the clinical state of xeroderma pigmentosum.
• XPC Gene Mutation|RAD4 Gene Mutation|XP3 Gene Mutation|XPC Complex Subunit, DNA Damage Recognition and Repair Factor Gene Mutation|XPCC Gene Mutation|Xeroderma Pigmentosum, Complementation Group C Gene Mutation-. a change in the nucleotide sequence of the xpc gene.
• XPC NP_004619.3:p.S346P|DNA Repair Protein Complementing XP-C Cells S346P|DNA Repair Protein Complementing XP-C Cells Ser346Pro|NP_004619.3:p.S346P|NP_004619.3:p.Ser346Pro|XPC NP_004619.3:p.Ser346Pro|XPC S346P|XPC Ser346Pro|XPC p.S346P|XPC p.Ser346Pro|Xeroderma Pigmentosum Group C Protein S346P|Xeroderma Pigmentosum Group C Protein Ser346Pro-. a change in the amino acid residue at position 346 in the dna repair protein complementing xp-c cells where serine has been replaced by proline.
• XPC Protein Variant|DNA Repair Protein Complementing XP-C Cells Protein Variant|Xeroderma Pigmentosum Group C Protein Variant-. a variation in the amino acid sequence for the dna repair protein complementing xp-c cells.
• XPC wt Allele|RAD4|RAD4, Yeast, Homolog of Gene|XP3|XPC Complex Subunit, DNA Damage Recognition and Repair Factor wt Allele|XPCC|Xeroderma Pigmentosum, Complementation Group C Gene-. human xpc wild-type allele is located in the vicinity of 3p25 and is approximately 34 kb in length. this allele, which encodes dna repair protein complementing xp-c cells protein, plays a role in the regulation of nucleotide excision repair. mutation of the gene is associated with xeroderma pigmentosum complementation group c.

Diagnostic Related Groups - MS-DRG Mapping

The is diagnosis code is grouped in the following groups for version MS-DRG V40.0 What are Diagnostic Related Groups?
The Diagnostic Related Groups (DRGs) are a patient classification scheme which provides a means of relating the type of patients a hospital treats. The DRGs divides all possible principal diagnoses into mutually exclusive principal diagnosis areas referred to as Major Diagnostic Categories (MDC). applicable from 10/01/2022 through 09/30/2023.

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Patient Education

Rashes

A rash is an area of irritated or swollen skin. Many rashes are itchy, red, painful, and irritated. Some rashes can also lead to blisters or patches of raw skin. Rashes are a symptom of many different medical problems. Other causes include irritating substances and allergies. Certain genes can make people more likely to get rashes.

Contact dermatitis is a common type of rash. It causes redness, itching, and sometimes small bumps. You get the rash where you have touched an irritant, such as a chemical, or something you are allergic to, like poison ivy.

Some rashes develop right away. Others form over several days. Although most rashes clear up fairly quickly, others are long-lasting and need long-term treatment.

Because rashes can be caused by many different things, it's important to figure out what kind you have before you treat it. If it is a bad rash, if it does not go away, or if you have other symptoms, you should see your health care provider. Treatments may include moisturizers, lotions, baths, cortisone creams that relieve swelling, and antihistamines, which relieve itching.

Ichthyosis

Code History

• FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
• FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
• FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
• FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
• FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
• FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
• FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
• FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016 (First year ICD-10-CM implemented into the HIPAA code set)