2026 ICD-10-CM Diagnosis Code H35.21Other non-diabetic proliferative retinopathy, right eye

ICD-10-CM Codes›H00–H59›H30-H36›H35

ICD-10-CM H35.21
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

H35.21 is a billable ICD-10-CM diagnosis code for other non-diabetic proliferative retinopathy, right eye. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 124 through 125. Coders also document this condition as proliferative vitreoretinopathy. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Retinal and vitreous conditions.

Code Identity

ICD-10-CM Code
H35.21
Billable Status
Yes — Valid for Submission
Code Describes
Other non-diabetic proliferative retinopathy, right eye
Short Description
Other non-diabetic proliferative retinopathy, right eye
Same as the full description in the CMS dataset.
Parent Code
H35.2
Other non-diabetic proliferative retinopathy

Code Classification

ChapterH00–H59Diseases of the eye and adnexa
SectionH30-H36Disorders of choroid and retina
CategoryH35Other retinal disorders
This CodeH35.21Other non-diabetic proliferative retinopathy, right eye

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Proliferative vitreoretinopathy
  • Proliferative vitreoretinopathy of right eye
  • Vitreous detachment of right eye

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR EYE005
Retinal and vitreous conditions
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Retinal Disorders

The retina is a layer of tissue in the back of your eye that senses light and sends images to your brain. In the center of this nerve tissue is the macula. It provides the sharp, central vision needed for reading, driving and seeing fine detail.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert H35.21 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
362.29 Prolif retinopathy NEC
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About H35.21Overview

Is H35.21 (Other non-diabetic proliferative retinopathy) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report other non-diabetic proliferative retinopathy, right eye on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does H35.21 group to?

When other non-diabetic proliferative retinopathy, right eye is the principal diagnosis on an inpatient stay, it groups to MS-DRG 124, 125, with relative weights from 0.7678 to 1.3231 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of H35.21?

Under the General Equivalence Mappings, other non-diabetic proliferative retinopathy, right eye converts to ICD-9-CM 362.29 (prolif retinopathy NEC). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.