2027 ICD-10-CM Diagnosis Code G44.41Drug-induced headache, not elsewhere classified, intractable

ICD-10-CM Codes›G00–G99›G40-G47›G44

ICD-10-CM G44.41
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

G44.41 is a billable ICD-10-CM diagnosis code for drug-induced headache, not elsewhere classified, intractable. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 102 through 103. Coders also document this condition as headache caused by drug. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Drug induced or toxic related condition and Headache; including migraine.

Code Identity

ICD-10-CM Code
G44.41
Billable Status
Yes — Valid for Submission
Code Describes
Drug-induced headache, not elsewhere classified, intractable
Short Description
Drug-induced headache, not elsewhere classified, intractable
Same as the full description in the CMS dataset.
Parent Code
Drug-induced headache, not elsewhere classified

Code Classification

ChapterG00–G99Diseases of the nervous system
SectionG40-G47Episodic and paroxysmal disorders
CategoryG44Other headache syndromes
This CodeG44.41Drug-induced headache, not elsewhere classified, intractable

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Headache caused by drug
  • Intractable headache caused by drug

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to G44.41: its own notes plus those printed at G44.4, G44, and Chapter 6. A note printed at a category, block or chapter applies to every code under it.

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From G44 Other headache syndromes applies to 40 codes

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From G44 Other headache syndromes applies to 40 codes
  • atypical facial pain (G50.1)
  • headache due to lumbar puncture (G97.1)
  • migraines (G43.-)
  • trigeminal neuralgia (G50.0)
From Chapter 6 (G00-G99) Diseases of the nervous system applies to 700 codes
  • certain conditions originating in the perinatal period (P04-P96)
  • certain infectious and parasitic diseases (A00-B99)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

From G44.4 Drug-induced headache, not elsewhere classified applies to 2 codes
  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name G44.41, its category, or a range that includes it.

Excludes2 4

These codes carry an Excludes2 note naming G44.41: its condition is not part of those codes, and both may be reported when the patient has both.

  • G43 Migraine
    headache syndromes (G44.-) names G44.-, which includes this code
  • G44.1 Vascular headache, not elsewhere classified
    drug-induced headache (G44.4-) names G44.4-, which includes this code
  • G89 Pain, not elsewhere classified
    headache syndromes (G44.-) names G44.-, which includes this code
  • R51 Headache
    migraine and other headache syndromes (G43-G44) names G43-G44, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INJ030
Drug induced or toxic related condition
Default principal diagnosis: inpatient Yes · outpatient Yes
CCSR NVS010
Headache; including migraine
Default principal diagnosis: inpatient No · outpatient No

Patient EducationClinical

Drug Reactions

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.

The full article covers:

  • What is a drug interaction?
  • What are side effects?
  • What are drug allergies?
  • How can I stay safe when taking medicines?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert G44.41 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
339.3 Drug induce headache NEC
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About G44.41Overview

What is the ICD-10 code for drug-induced headache, not elsewhere classified, intractable?

The ICD-10-CM code for drug-induced headache, not elsewhere classified, intractable is G44.41 (sometimes written as G4441). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is G44.41 (Drug-induced headache, not elsewhere classified) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report drug-induced headache, not elsewhere classified, intractable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does G44.41 group to?

When drug-induced headache, not elsewhere classified, intractable is the principal diagnosis on an inpatient stay, it groups to MS-DRG 102, 103, with relative weights from 0.8219 to 1.1200 depending on complications. Higher weights mean higher Medicare reimbursement.

Can G44.41 be reported with R51.9?

Not as a rule. The Excludes1 note at G44, which applies to G44.41, lists "headache NOS (R51.9)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

Does G44.41 need an additional code?

When the condition applies, yes. The Use Additional Code note at G44.4, which applies to G44.41, reads: code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5). The additional code is reported after G44.41.