2027 ICD-10-CM Diagnosis Code E89.6Postprocedural adrenocortical (-medullary) hypofunction
ICD-10-CM Codes›E00–E89›E89›E89
- Billable — Valid for Submission
- CC — Complication or Comorbidity
- Not Chronic
E89.6 is a billable ICD-10-CM diagnosis code for postprocedural adrenocortical (-medullary) hypofunction. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 643 through 645. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 22 closely related codes. Coders also document this condition as adrenocortical hypofunction following procedure. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Postprocedural or postoperative endocrine or metabolic complication.
E89.6 no longer risk-adjusts for Medicare Advantage: it mapped to HCC 23 under the retired CMS-HCC V24 model through payment year 2025 but maps to no category in the live V28 model. It still risk-adjusts in the PACE (CMS-HCC V22) category 23, ESRD (V21) category 23, ESRD (V24) category 23, and RxHCC Part D (V08) category 43 for payment year 2027.
Code Identity
Code Classification
Medicare Risk Adjustment (HCC)Billing
E89.6 no longer risk-adjusts for Medicare Advantage: it maps to no payment category in the live CMS-HCC V28 model, although it still risk-adjusts in the other CMS models shown below.
Source: CMS Payment Year 2027 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Adrenocortical hypofunction following procedure
- History of adrenalectomy
- History of excision of endocrine gland
- Post-adrenalectomy adrenal insufficiency
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to E89.6: its own notes plus those printed at E89 and Chapter 4. A note printed at a category, block or chapter applies to every code under it.
Excludes1
Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
Notes
General instructions on how these codes are used.
- All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Referenced in Other NotesGuidance
Instructional notes printed at other codes that name E89.6, its category, or a range that includes it.
Excludes2 4
These codes carry an Excludes2 note naming E89.6: its condition is not part of those codes, and both may be reported when the patient has both.
- E36 Intraoperative complications of endocrine systempostprocedural endocrine and metabolic complications and disorders, not elsewhere classified (E89.-) names E89.-, which includes this code
- Block T80-T88 Complications of surgical and medical care, not elsewhere classifiedintraoperative and postprocedural complications of specified body systems (D78.-, E36.-, E89.-, G97.3-, G97.4, H59.3-, H59.-, H95.2-, H95.3, I97.4-, I97.5, J95.6-, J95.7, K91.6-, L76.-, M96.-, N99.-) names E89.-, which includes this code
- T81 Complications of procedures, not elsewhere classifiedintraoperative and postprocedural complications of specific body system (D78.-, E36.-, E89.-, G97.3-, G97.4, H59.3-, H59.-, H95.2-, H95.3, I97.4-, I97.5, J95, K91.-, L76.-, M96.-, N99.-) names E89.-, which includes this code
- Z90 Acquired absence of organs, not elsewhere classifiedpostprocedural absence of endocrine glands (E89.-) names E89.-, which includes this code
Index to Diseases and InjuriesGuidance
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Patient EducationClinical
Adrenal Gland Disorders
Your adrenal glands are two small organs that sit on top of each kidney. The adrenal glands make different types of hormones you need to stay alive and healthy. Hormones are chemicals that travel in your bloodstream and control how different parts of your body work.
The full article covers:
- What are adrenal glands?
- What are adrenal gland disorders?
- What causes adrenal gland disorders?
- How are adrenal gland disorders diagnosed?
- What are the treatments for adrenal gland disorders?
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert E89.6 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About E89.6Overview
What is the ICD-10 code for postprocedural adrenocortical (-medullary) hypofunction?
The ICD-10-CM code for postprocedural adrenocortical (-medullary) hypofunction is E89.6 (sometimes written as E896). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is E89.6 a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report postprocedural adrenocortical (-medullary) hypofunction on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does E89.6 group to?
When postprocedural adrenocortical (-medullary) hypofunction is the principal diagnosis on an inpatient stay, it groups to MS-DRG 644, 645, 643, with relative weights from 0.7461 to 1.6138 depending on complications. Higher weights mean higher Medicare reimbursement.
Is E89.6 a CC or MCC?
CMS lists E89.6 as a CC (complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 22 closely related codes in its exclusion list.
What is the ICD-9 equivalent of E89.6?
Under the General Equivalence Mappings, postprocedural adrenocortical (-medullary) hypofunction converts to ICD-9-CM 255.41 (glucocorticoid deficient). The mapping is approximate, so confirm the match fits the documentation.
Does E89.6 risk-adjust for Medicare Advantage payment?
Not for Medicare Advantage. E89.6 mapped to HCC 23 in the retired CMS-HCC V24 model, which last determined payment in 2025, but it maps to no category in the live V28 model; see all codes that no longer risk-adjust. It still risk-adjusts in the PACE (CMS-HCC V22) category 23 (Other Significant Endocrine and Metabolic Disorders), ESRD (V21) category 23 (Other Significant Endocrine and Metabolic Disorders), ESRD (V24) category 23 (Other Significant Endocrine and Metabolic Disorders), and RxHCC Part D (V08) category 43 (Pituitary, Adrenal Gland, and Other Endocrine and Metabolic Disorders).
