Valid for Submission
D89.82 is a billable diagnosis code used to specify a medical diagnosis of autoimmune lymphoproliferative syndrome [alps]. The code D89.82 is valid during the fiscal year 2022 from October 01, 2021 through September 30, 2022 for the submission of HIPAA-covered transactions.
The ICD-10-CM code D89.82 might also be used to specify conditions or terms like autoimmune lymphoproliferative syndrome, autoimmune lymphoproliferative syndrome with recurrent viral infection, dianzani autoimmune lymphoproliferative disease or ras-associated autoimmune leukoproliferative disease.
Index to Diseases and Injuries
The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code(s). The following references for the code D89.82 are found in the index:
The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:
- Autoimmune lymphoproliferative syndrome
- Autoimmune lymphoproliferative syndrome with recurrent viral infection
- Dianzani autoimmune lymphoproliferative disease
- RAS-associated autoimmune leukoproliferative disease
- AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME-. rare congenital lymphoid disorder due to mutations in certain fas fas ligand pathway genes. known causes include mutations in fas tnfsf6 nras casp8 and casp10 proteins. clinical features include lymphadenopathy; splenomegaly; and autoimmunity.
Diagnostic Related Groups - MS-DRG Mapping
|MS-DRG||MS-DRG Title||MCD||Relative Weight|
|545||CONNECTIVE TISSUE DISORDERS WITH MCC||08||2.4995|
|546||CONNECTIVE TISSUE DISORDERS WITH CC||08||1.2066|
|547||CONNECTIVE TISSUE DISORDERS WITHOUT CC/MCC||08||0.833|
The relative weight of a diagnostic related group determines the reimbursement rate based on the severity of a patient's illness and the associated cost of care during hospitalization.
Convert D89.82 to ICD-9 Code
Information for Patients
Your body's immune system protects you from disease and infection. But if you have an autoimmune disease, your immune system attacks healthy cells in your body by mistake. Autoimmune diseases can affect many parts of the body.
No one is sure what causes autoimmune diseases. They do tend to run in families. Women - particularly African American, Hispanic American, and Native American women - have a higher risk for some autoimmune diseases.
There are more than 80 types of autoimmune diseases, and some have similar symptoms. This makes it hard for your health care provider to know if you really have one of these diseases, and if so, which one. Getting a diagnosis can be frustrating and stressful. Often, the first symptoms are fatigue, muscle aches and a low fever. The classic sign of an autoimmune disease is inflammation, which can cause redness, heat, pain and swelling.
The diseases may also have flare-ups, when they get worse, and remissions, when symptoms get better or disappear. Treatment depends on the disease, but in most cases one important goal is to reduce inflammation. Sometimes doctors prescribe corticosteroids or other drugs that reduce your immune response.
[Learn More in MedlinePlus]
The lymphatic system is a network of tissues and organs. It is made up of
- Lymph - a fluid that contains white blood cells that defend against germs
- Lymph vessels - vessels that carry lymph throughout your body. They are different from blood vessels.
- Lymph nodes - glands found throughout the lymph vessels. Along with your spleen, these nodes are where white blood cells fight infection.
Your bone marrow and thymus produce the cells in lymph. They are part of the system, too.
The lymphatic system clears away infection and keeps your body fluids in balance. If it's not working properly, fluid builds in your tissues and causes swelling, called lymphedema. Other lymphatic system problems can include infections, blockage, and cancer.
[Learn More in MedlinePlus]
Autoimmune lymphoproliferative syndrome
Autoimmune lymphoproliferative syndrome (ALPS) is an inherited disorder in which the body cannot properly regulate the number of immune system cells (lymphocytes). ALPS is characterized by the production of an abnormally large number of lymphocytes (lymphoproliferation). Accumulation of excess lymphocytes results in enlargement of the lymph nodes (lymphadenopathy), the liver (hepatomegaly), and the spleen (splenomegaly).
Autoimmune disorders are also common in ALPS. Autoimmune disorders occur when the immune system malfunctions and attacks the body's own tissues and organs. Most of the autoimmune disorders associated with ALPS target and damage blood cells. For example, the immune system may attack red blood cells (autoimmune hemolytic anemia), white blood cells (autoimmune neutropenia), or platelets (autoimmune thrombocytopenia). Less commonly, autoimmune disorders that affect other organs and tissues occur in people with ALPS. These disorders can damage the kidneys (glomerulonephritis), liver (autoimmune hepatitis), eyes (uveitis), or nerves (Guillain-Barre syndrome). Skin problems, usually rashes or hives (urticaria), can also occur in ALPS.
ALPS can have varying patterns of signs and symptoms. Most commonly, lymphoproliferation becomes apparent during childhood. Enlargement of the lymph nodes and spleen frequently occur in affected individuals. Autoimmune disorders typically develop several years later, most frequently as a combination of hemolytic anemia and thrombocytopenia, also called Evans syndrome. People with this classic form of ALPS generally have a near-normal lifespan, but have a greatly increased risk of developing cancer of the immune system cells (lymphoma) compared with the general population.
Some people have signs and symptoms that resemble those of ALPS, including lymphoproliferation, lymphadenopathy, splenomegaly, and low blood counts, but the specific pattern of these signs and symptoms or the genetic cause may be different. Researchers disagree whether individuals with these non-classic forms should be considered to have ALPS or a separate condition.
[Learn More in MedlinePlus]