2026 ICD-10-CM Diagnosis Code D72.89Other specified disorders of white blood cells

ICD-10-CM Codes›D50–D89›D70-D77›D72

ICD-10-CM D72.89
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D72.89 is a billable ICD-10-CM diagnosis code for other specified disorders of white blood cells. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 814 through 816. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Diseases of white blood cells.

Code Identity

ICD-10-CM Code
D72.89
Billable Status
Yes — Valid for Submission
Code Describes
Other specified disorders of white blood cells
Short Description
Other specified disorders of white blood cells
Same as the full description in the CMS dataset.
Parent Code
D72.8
Other specified disorders of white blood cells

Code Classification

ChapterD50–D89Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
SectionD70-D77Other disorders of blood and blood-forming organs
CategoryD72Other disorders of white blood cells
This CodeD72.89Other specified disorders of white blood cells

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Abnormal basophil production
  • Abnormal eosinophil production
  • Abnormal granulocyte production
  • Abnormal monocyte production
  • Abnormal monocytes
  • Acquired disorder of neutrophil function
  • Adult G6PD deficiency of leukocytes syndrome
  • Alder-Reilly body
  • Alius-Grignaschi anomaly
  • Basophilic hyperplasia
  • Chemotactic disorder
  • Congenital neutrophil actin dysfunction
  • Cytoplasmic vacuolation
  • Cytoplasmic vacuolation of lymphocyte
  • Decreased granulocyte life span
  • Decreased lymphocyte destruction
  • Decreased lymphocyte life span
  • Defective phagocytic cell adhesion
  • Defective phagocytic cell chemotaxis
  • Defective phagocytic cell killing
  • Defective phagocytic cell opsonization
  • Disorder of basophils
  • Disorder of neutrophil adhesion
  • Disorder of neutrophil chemotaxis
  • Disorder of phagocytic cell number
  • Disorder of the gamma-glutamyl cycle
  • Döhle body
  • Drumstick nuclear appendage
  • Eosinophil peroxidase deficiency
  • Extramedullary hematopoiesis
  • Extramedullary megakaryocytopoiesis
  • Giant granulation
  • Glutathione synthetase deficiency
  • Gluthathione peroxidase deficiency
  • Granulation anomaly
  • Granulocyte abnormality due to immune defect
  • Granulocyte destruction finding
  • Granulocyte granule deficiency
  • Heritable disorder of neutrophil function
  • Heritable disorder of neutrophil production
  • Immature white blood cells
  • Increased granulocyte destruction
  • Increased lymphocyte destruction
  • Increased lymphocyte production
  • Increased megakaryocyte production
  • Jung syndrome
  • Left shifted white blood cells
  • Leukocyte adhesion deficiency
  • Leukocyte glucose-6-phosphate dehydrogenase deficiency
  • Leukocyte maturation arrest
  • Lymphocyte abnormality
  • Lymphocyte finding
  • Lymphocytoid disorder
  • Monocyte finding
  • Morulae in leukocyte
  • Myeloperoxidase deficiency
  • Myeloperoxidase deficiency syndrome
  • Neutrophil abnormality
  • Neutrophil cytomatrix disorder
  • Neutrophil motility disorder
  • Neutrophil secondary granule deficiency
  • Non malignant mast cell disease
  • Pelger-Huët cell
  • Periodontitis due to leukocyte adhesion deficiency
  • Phagocytic cell defect
  • Phagocytic cell dysfunction
  • Plasmacytoid lymphocytes
  • Platycytes
  • Pseudoneutrophilia
  • Pseudo-Pelger-Huet form
  • Quantitative disorder of neutrophils
  • Reactive mastocytosis
  • Recurrent infection due to specific granule deficiency
  • Right shifted white blood cells
  • Ring-form neutrophil
  • Sensitized cell
  • Sensitized leukocyte
  • Siccardi syndrome
  • Specific granule deficiency
  • Toxic granulation
  • White blood cell abnormality
  • White blood cell age - finding
  • White blood cell chromosome abnormality
  • White blood cell granularity - finding

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Abnormality of white blood cells NEC

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Abnormal, abnormality, abnormalities
      • white blood cells
        • specified NEC
    • Disease, diseased
      • white blood cells
        • specified NEC
    • Disorder(of)
      • white blood cells
        • specified NEC
    • Hypoeosinophilia

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR BLD007
Diseases of white blood cells
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Leukocyte Adhesion Deficiency

    a rare autosomal recessive immunodeficiency disorder caused by deficiency of cd18 expression. it is characterized by defects in neutrophil adhesion and bacterial infections.

  • Leukocyte Adhesion Deficiency Type 1|LAD-1|LAD-1 Deficiency|LAD-Type I|LAD1|LFA-I Deficiency|LFA1 Immunodeficiency

    a rare immunodeficiency with an autosomal recessive pattern of inheritance. it is caused by mutation in the itgb2 gene on chromosome 21 which codes for the beta subunit of beta-2 integrin (cd18). the mutation results in significantly reduced or absent expression of cd18 on the surface of leukocytes which impairs their ability to migrate and interact with antigens. initial clinical signs include omphalitis and delayed separation of the umbilical cord. the clinical course is marked by recurrent bacterial and fungal infection without pus formation. in instances where there is < 1% expression of cd18, prognosis is dismal with a high likelihood for life-threatening infection within the first year of life.

  • Leukocyte Adhesion Deficiency Type 2|CDGIIc|Congenital Disorder of Glycosylation Type IIc|LAD-Type II|Sialyl-Lewis X Defect

    leukocyte adhesion deficiency, type ii. an inherited disease affecting the metabolism of fucose, which affects the expression of the sialyl lewis x antigen, the fucose-containing ligand for e- and p-selectins, resulting in a deficiency in neutrophil adhesion. syn sialyl-lewis x defect.

  • Leukocyte Adhesion Deficiency Type 3|LAD-3|LAD-III

    an autosomal recessive condition caused by mutation(s) in the fermt3 gene, encoding fermitin family homolog 3. it is characterized by a defect in activation of all beta integrins. it manifests clinically as severe infections with marked leukocytosis, accompanied by life-threatening bleeding episodes.

Patient EducationClinical

Blood Disorders

Your blood is living tissue made up of liquid and solids. The liquid part, called plasma, is made of water, salts and protein. Over half of your blood is plasma. The solid part of your blood contains red blood cells, white blood cells and platelets.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D72.89 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
288.8 Wbc disease NEC
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D72.89Overview

Is D72.89 (Other specified disorders of white blood cells) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report other specified disorders of white blood cells on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does D72.89 group to?

When other specified disorders of white blood cells is the principal diagnosis on an inpatient stay, it groups to MS-DRG 814, 815, 816, with relative weights from 0.6320 to 2.1267 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of D72.89?

Under the General Equivalence Mappings, other specified disorders of white blood cells converts to ICD-9-CM 288.8 (wbc disease NEC). The mapping is a direct match.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.