2024 ICD-10-CM Diagnosis Code D72.823

Leukemoid reaction

ICD-10-CM Code:
ICD-10 Code for:
Leukemoid reaction
Is Billable?
Yes - Valid for Submission
Chronic Condition Indicator: [1]
Not chronic
Code Navigator:

Code Classification

  • Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
    • Other disorders of blood and blood-forming organs
      • Other disorders of white blood cells

D72.823 is a billable diagnosis code used to specify a medical diagnosis of leukemoid reaction. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024.

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Basophilic leukemoid reaction
  • Blood monocyte number above reference range
  • Complete trisomy 21 syndrome
  • Down syndrome co-occurrent with leukemoid reaction associated transient neonatal pustulosis
  • Leukemoid reaction
  • Leukemoid reaction
  • Leukemoid reaction of the newborn
  • Lymphocytic leukemoid reaction
  • Monocyte count - finding
  • Monocyte count outside reference range
  • Monocytic leukemoid reaction
  • Monocytoid disorder
  • Monocytosis
  • Neutrophilia disorder
  • Neutrophilic leukemoid reaction
  • Non-malignant lymphocyte AND/OR plasma cell disorder
  • Pustule
  • Transient neonatal pustulosis

Clinical Classification

Clinical Information

  • Leukemoid Reaction

    a peripheral blood picture resembling that of leukemia or indistinguishable from it on the basis of morphologic appearance alone. (dorland, 27th ed)
  • Leukemoid Reaction

    a hematology test result that indicates the presence of an increased white blood cell count and increased neutrophil precursors resembling leukemia, in a peripheral blood smear.
  • Transient Leukemoid Reaction of the Newborn|Leukemoid Reaction of the Newborn|Transient Leukemoid Reaction of Newborn

    increased white blood cell count and increased neutrophil precursors resembling leukemia in a neonate or fetus. often, this is a response to medications received, infection or down syndrome.
  • Clonal Cytopenia with Monocytosis of Undetermined Significance|CCMUS

    a myelodysplastic/myeloproliferative neoplasm that fulfills the diagnostic criteria of clonal monocytosis of undetermined significance and is associated with cytopenia.
  • Clonal Monocytosis of Undetermined Significance|CMUS

    a myelodysplastic/myeloproliferative neoplasm characterized by the presence of persistent monocytosis, presence of at least one myeloid neoplasm-associated mutation, absence of significant dysplasia or increased blasts in the bone marrow, absence of morphologic findings suggestive of chronic myelomonocytic leukemia in the bone marrow, and absence of history of a reactive condition that would explain the persistent monocytosis.
  • Monocytosis

    abnormally high level of monocytes in the blood.

Tabular List of Diseases and Injuries

The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.

Inclusion Terms

Inclusion Terms
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
  • Basophilic leukemoid reaction
  • Leukemoid reaction NOS
  • Lymphocytic leukemoid reaction
  • Monocytic leukemoid reaction
  • Myelocytic leukemoid reaction
  • Neutrophilic leukemoid reaction

Index to Diseases and Injuries References

The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).

Convert D72.823 to ICD-9-CM

  • ICD-9-CM Code: 288.62 - Leukemoid reaction

Patient Education

Blood Disorders

Your blood is living tissue made up of liquid and solids. The liquid part, called plasma, is made of water, salts and protein. Over half of your blood is plasma. The solid part of your blood contains red blood cells, white blood cells and platelets.

Blood disorders affect one or more parts of the blood and prevent your blood from doing its job. They can be acute or chronic. Many blood disorders are inherited. Other causes include other diseases, side effects of medicines, and a lack of certain nutrients in your diet.

Types of blood disorders include:

  • Platelet disorders, excessive clotting, and bleeding problems, which affect how your blood clots
  • Anemia, which happens when your blood does not carry enough oxygen to the rest of your body
  • Cancers of the blood, such as leukemia and myeloma
  • Eosinophilic disorders, which are problems with one type of white blood cell.

[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.


[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.