2026 ICD-10-CM Diagnosis Code D72.118Other hypereosinophilic syndrome

ICD-10-CM Codes›D50–D89›D70-D77›D72

ICD-10-CM D72.118
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D72.118 is a billable ICD-10-CM diagnosis code for other hypereosinophilic syndrome. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 814 through 816. Coders also document this condition as hypereosinophilic syndrome. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Diseases of white blood cells.

Code Identity

ICD-10-CM Code
D72.118
Billable Status
Yes — Valid for Submission
Code Describes
Other hypereosinophilic syndrome
Short Description
Other hypereosinophilic syndrome
Same as the full description in the CMS dataset.
Parent Code
D72.11
Hypereosinophilic syndrome [HES]

Code Classification

ChapterD50–D89Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
SectionD70-D77Other disorders of blood and blood-forming organs
CategoryD72Other disorders of white blood cells
This CodeD72.118Other hypereosinophilic syndrome

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Hypereosinophilic syndrome
  • Myeloproliferative hypereosinophilic syndrome
  • Primary hypereosinophilic syndrome

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Episodic angioedema with eosinophilia
  • Gleich's syndrome

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR BLD007
Diseases of white blood cells
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Hypereosinophilic Syndrome

    a heterogeneous group of disorders with the common feature of prolonged eosinophilia of unknown cause and associated organ system dysfunction, including the heart, central nervous system, kidneys, lungs, gastrointestinal tract, and skin. there is a massive increase in the number of eosinophils in the blood, mimicking leukemia, and extensive eosinophilic infiltration of the various organs.

  • Eosinophils

    granular leukocytes with a nucleus that usually has two lobes connected by a slender thread of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and stainable by eosin.

Patient EducationClinical

Eosinophilic Disorders

Eosinophils are a type of white blood cell. They help fight off infections and play a role in your body's immune response. They can also build up and cause inflammation.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code History & ChangesHistory

Replacement D72.118 replaces the following previously assigned code(s):

  • D72.1 - Eosinophilia
FY 2021AddedAdded to the ICD-10-CM code setEffective October 1, 2020.
FY 2022–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D72.118Overview

What is the ICD-10 code for other hypereosinophilic syndrome?

The ICD-10-CM code for other hypereosinophilic syndrome is D72.118 (sometimes written as D72118). It is billable on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

Is D72.118 (Hypereosinophilic syndrome [HES]) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report other hypereosinophilic syndrome on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does D72.118 group to?

When other hypereosinophilic syndrome is the principal diagnosis on an inpatient stay, it groups to MS-DRG 814, 815, 816, with relative weights from 0.6320 to 2.1267 depending on complications. Higher weights mean higher Medicare reimbursement.