2026 ICD-10-CM Diagnosis Code D69.1Qualitative platelet defects
ICD-10-CM Codes›D50–D89›D65-D69›D69
- Billable — Valid for Submission
- Chronic Condition
D69.1 is a billable ICD-10-CM diagnosis code for qualitative platelet defects. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Coagulation and hemorrhagic disorders.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Abnormal platelet destruction
- Abnormal platelet production
- Acquired PF-3 disease
- Acquired platelet disorder
- Acquired platelet function disorder
- Acquired storage pool deficiency
- Asplenia
- Autoimmune state
- Autoplatelet sensitivity
- Autosensitivity
- Bernard Soulier syndrome
- Bleeding diathesis due to collagen receptor defect
- Congenital dyserythropoietic anemia
- Congenital dysmegakaryopoietic thrombocytopenia, Paris Trousseau type
- Congenital miosis
- Constricted pupil
- Cyclooxygenase deficiency
- Decreased platelet destruction
- Decreased platelet life span
- Dense body defect
- Exhausted platelets
- Familial alpha>2< adrenergic receptor defect in platelets
- Familial platelet syndrome with predisposition to acute myelogenous leukemia
- Giant platelet syndrome
- Glanzmann's thrombasthenia
- Glycoprotein Ia defect
- Glycoprotein Ib defect
- Glycoprotein VI deficiency
- Gray platelet syndrome
- Hereditary platelet function disorder
- Increased platelet destruction
- Ineffective thrombopoiesis
- Inherited platelet disorder
- Isolated collagen aggregation defect
- Medich giant platelet syndrome
- Mediterranean macrothrombocytopenia
- Megakaryocyte finding
- Megakaryocytic thrombocytopenia
- Mixed alpha granule and dense body deficiency
- Montreal platelet syndrome
- Platelet clumps
- Platelet dense granule deficiency
- Platelet disorder
- Platelet dysfunction associated with uremia
- Platelet dysfunction caused by aspirin
- Platelet membrane defect
- Platelet morphology - finding
- Platelet procoagulant activity deficiency
- Platelet production finding
- Platelet satellite
- Platelet secretory disorder
- Platelet sequestration
- Platelet storage pool defect
- Qualitative platelet disorder
- Scott syndrome
- Sensitized cell
- Sensitized platelet
- Thrombocytopathy, asplenia and miosis
- Thromboxane generation defect
- Thromboxane synthetase deficiency
- White platelet syndrome
- X-linked dyserythropoietic anemia with abnormal platelets and neutropenia
Tabular List NotesGuidance
Coding notes and annotation back-references applicable to this code.
Inclusion Terms
- Bernard-Soulier giant platelet syndrome
- Glanzmann's disease
- Grey platelet syndrome
- Thromboasthenia (hemorrhagic) (hereditary)
- Thrombocytopathy
Type 1 Excludes
- hemolytic-uremic syndrome D59.3
Type 2 Excludes
- von Willebrand disease D68.0
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
A type 2 excludes note represents "Not included here". An excludes2 note indicates that the condition excluded is not part of the condition represented by the code, but a patient may have both conditions at the same time. When an Excludes2 note appears under a code, it is acceptable to use both the code and the excluded code together, when appropriate.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
- Bernard-Soulier disease or thrombopathia - D69.1
- platelets, qualitative - D69.1
- platelet NEC - D69.1
- Diacyclothrombopathia - D69.1
- Disease, diseased - See Also: Syndrome;
- Bernard-Soulier (thrombopathy) - D69.1
- Glanzmann's (hereditary hemorrhagic thrombasthenia) - D69.1
- Naegeli's - D69.1
- Disorder (of) - See Also: Disease;
- platelets - D69.1
- platelets - D69.1
- Syndrome - See Also: Disease;
- giant platelet (Bernard-Soulier) - D69.1
- gray or grey (newborn) - P93.0
- platelet - D69.1
- Thrombocytasthenia (Glanzmann) - D69.1
- Thrombopathy (Bernard-Soulier) - D69.1
External Cause of Injuries IndexGuidance
References for this code in the External Cause of Injuries Index.
- Bernard-Soulier disease or thrombopathia
- Defect, defective
- platelets, qualitative
- Deficiency, deficient
- platelet NEC
- Diacyclothrombopathia
- Disease, diseased
- Bernard-Soulier (thrombopathy)
- Disease, diseased
- Glanzmann's (hereditary hemorrhagic thrombasthenia)
- Disease, diseased
- Naegeli's
- Disorder(of)
- platelets
- Dysfunction
- platelets
- Glanzmann(-Naegeli) disease or thrombasthenia
- Syndrome
- giant platelet (Bernard-Soulier)
- Syndrome
- gray or grey (newborn)
- platelet
- Thrombasthenia(Glanzmann) (hemorrhagic) (hereditary)
- Thromboasthenia(Glanzmann) (hemorrhagic) (hereditary)
- Thrombocytasthenia(Glanzmann)
- Thrombocytopathy(dystrophic) (granulopenic)
- Thrombopathy(Bernard-Soulier)
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Gray Platelet Syndrome
a rare, inherited platelet disorder characterized by a selective deficiency in the number and contents of platelet alpha-granules. it is associated with thrombocytopenia, enlarged platelets, and prolonged bleeding time.Thrombocytopenia
a subnormal level of blood platelets.CDAN1 Gene|CDAN1|CDAN1|Congenital Dyserythropoietic Anemia, Type I Gene
this gene may be involved in nuclear membrane maintenance.CDAN1 wt Allele|CDA-I|CDA1|CDAI|Codanin Gene|Congenital Dyserythropoietic Anemia, Type I wt Allele|DLT|Discs Lost Homolog Gene|Discs Lost, Drosophila, Homolog of Gene|PRO1295|UNQ664/PRO1295
human cdan1 wild-type allele is located in the vicinity of 15q15.2 and is approximately 14 kb in length. this allele, which encodes codanin-1 protein, may play a role in the maintenance of the nuclear envelope. mutation of the gene is associated with congenital dyserythropoietic anemia type i.Congenital Dyserythropoietic Anemia
a rare group of disorders that result in anemia that is caused by ineffective erythropoiesis, which is associated with multinuclear erythroblasts, and which may present in childhood. the most common mutations are in the cdan1 and sec23b genes.Congenital Dyserythropoietic Anemia Type II|CDA II|CDAN2|HEMPAS|Hereditary Erythroblastic Multinuclearity with Positive Acidified-Serum Test|SEC23B-CDG
an autosomal recessive subtype of congenital dyserythropoietic anemia caused by mutation(s) in the sec23b gene, encoding protein transport protein sec23b.Congenital Dyserythropoietic Anemia Type IV|CDAN4
an autosomal dominant sub-type of congenital dyserythropoietic anemia caused by mutation(s) in the klf1 gene, encoding krueppel-like factor 1.SEC23B wt Allele|CDA-II|CDAII|CDAN2|Congenital Dyserythropoietic Anemia, Type II Gene|HEMPAS|RP11-379J5.1|Sec23 Homolog B (S. cerevisiae) wt Allele
human sec23b wild-type allele is located in the vicinity of 20p11.23 and is approximately 54 kb in length. this allele, which encodes protein transport protein sec23b, is involved in the transport of vesicles from the endoplasmic reticulum to the golgi. mutation of the gene is associated with congenital dyserythropoietic anemia type ii.
Patient EducationClinical
Platelet Disorders
Platelets, also known as thrombocytes, are blood cells. They form in your bone marrow, a sponge-like tissue in your bones. Platelets play a major role in blood clotting. Normally, when one of your blood vessels is injured, you start to bleed.
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert D69.1 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About D69.1Overview
Is D69.1 (Purpura and other hemorrhagic conditions) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report qualitative platelet defects on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
What is the ICD-9 equivalent of D69.1?
Under the General Equivalence Mappings, qualitative platelet defects converts to ICD-9-CM 287.1 (thrombocytopathy). The mapping is a direct match.
Footnotes
[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:
- The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
- The condition places limitations on self-care, independent living, and social interactions.
