2026 ICD-10-CM Diagnosis Code D59.32Hereditary hemolytic-uremic syndrome

ICD-10-CM Codes›D50–D89›D55-D59›D59

ICD-10-CM D59.32
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D59.32 is a billable ICD-10-CM diagnosis code for hereditary hemolytic-uremic syndrome. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 811 through 812. Coders also document this condition as congenital hemolytic uremic syndrome. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Hemolytic anemia.

Code Identity

ICD-10-CM Code
D59.32
Billable Status
Yes — Valid for Submission
Code Describes
Hereditary hemolytic-uremic syndrome
Short Description
Hereditary hemolytic-uremic syndrome
Same as the full description in the CMS dataset.
Parent Code
D59.3
Hemolytic-uremic syndrome

Code Classification

ChapterD50–D89Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
SectionD55-D59Hemolytic anemias
CategoryD59Acquired hemolytic anemia
This CodeD59.32Hereditary hemolytic-uremic syndrome

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Congenital hemolytic uremic syndrome
  • Hemolytic uremic syndrome with DGKE deficiency

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Atypical hemolytic uremic syndrome with an identified genetic cause

Code Also

  • , if applicable:
  • defects in the complement system D84.1
  • methylmalonic acidemia E71.120

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Syndrome
      • hemolytic-uremic
        • atypical
          • genetic
    • Syndrome
      • hemolytic-uremic
        • atypical
          • hereditary
    • Syndrome
      • hemolytic-uremic
        • due to genetic disorder
    • Syndrome
      • hemolytic-uremic
        • familial
    • Syndrome
      • hemolytic-uremic
        • hereditary

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR BLD002
Hemolytic anemia
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Kidney Diseases

You have two kidneys, each about the size of your fist. They are near the middle of your back, just below the rib cage. Inside each kidney there are about a million tiny structures called nephrons. They filter your blood. They remove wastes and extra water, which become urine. The urine flows through tubes called ureters.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code History & ChangesHistory

Replacement D59.32 replaces the following previously assigned code(s):

  • D59.3 - Hemolytic-uremic syndrome
FY 2023AddedAdded to the ICD-10-CM code setEffective October 1, 2022.
FY 2024–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D59.32Overview

Is D59.32 (Hemolytic-uremic syndrome) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report hereditary hemolytic-uremic syndrome on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does D59.32 group to?

When hereditary hemolytic-uremic syndrome is the principal diagnosis on an inpatient stay, it groups to MS-DRG 811, 812, with relative weights from 0.9182 to 1.4043 depending on complications. Higher weights mean higher Medicare reimbursement.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.