2027 ICD-10-CM Diagnosis Code D49.4Neoplasm of unspecified behavior of bladder

ICD-10-CM Codes›C00–D49›D49›D49

ICD-10-CM D49.4
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

D49.4 is a billable ICD-10-CM diagnosis code for neoplasm of unspecified behavior of bladder. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 656 through 658, 686 through 688. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Neoplasms of unspecified nature or uncertain behavior.

Code Identity

ICD-10-CM Code
D49.4
Billable Status
Yes — Valid for Submission
Code Describes
Neoplasm of unspecified behavior of bladder
Short Description
Neoplasm of unspecified behavior of bladder
Same as the full description in the CMS dataset.
Parent Code
D49
Neoplasms of unspecified behavior

Code Classification

ChapterC00–D49Neoplasms
SectionD49Neoplasms of unspecified behavior
CategoryD49Neoplasms of unspecified behavior
This CodeD49.4Neoplasm of unspecified behavior of bladder

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Mass of urinary bladder neck
  • Neoplasm of anterior wall of urinary bladder
  • Neoplasm of apex of urinary bladder
  • Neoplasm of dome of urinary bladder
  • Neoplasm of lateral wall of urinary bladder
  • Neoplasm of neck of urinary bladder
  • Neoplasm of posterior wall of urinary bladder
  • Neoplasm of trigone of urinary bladder
  • Neoplasm of urachus
  • Neoplasm of ureteric orifice of urinary bladder
  • Neoplasm of urinary bladder

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to D49.4: its own notes plus those printed at D49 and Chapter 2. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From D49 Neoplasms of unspecified behavior applies to 14 codes
  • 'growth' NOS
  • neoplasm NOS
  • new growth NOS
  • tumor NOS

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From D49 Neoplasms of unspecified behavior applies to 14 codes
  • neoplasms of uncertain behavior (D37-D44, D48)

Notes

General instructions on how these codes are used.

From D49 Neoplasms of unspecified behavior applies to 14 codes
  • Category D49 classifies by site neoplasms of unspecified morphology and behavior. The term 'mass', unless otherwise stated, is not to be regarded as a neoplastic growth.
From Chapter 2 (C00-D49) Neoplasms applies to 1,730 codes
  • Functional activity
  • All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
  • Morphology [Histology]
  • Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
  • Primary malignant neoplasms overlapping site boundaries
  • A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
  • Malignant neoplasm of ectopic tissue
  • Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name D49.4, its category, or a range that includes it.

Excludes1 1

These codes carry an Excludes1 note naming D49.4: they are not reported together with it, unless the two conditions are unrelated.

  • Block D37-D48 Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes
    neoplasms of unspecified behavior (D49.-) names D49.-, which includes this code

Notes 1

These notes mention D49.4.

  • D49 Neoplasms of unspecified behavior
    Category D49 classifies by site neoplasms of unspecified morphology and behavior. The term 'mass', unless otherwise stated, is not to be regarded as a neoplastic growth. names D49, which includes this code

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NEO072
Neoplasms of unspecified nature or uncertain behavior
Default principal diagnosis: inpatient Yes · outpatient Yes

Table of NeoplasmsClinical

Anatomical sites in the Table of Neoplasms that reference this code family.

SiteMalig.
Primary		Malig.
Secondary		Ca
in situ		BenignUncertainUnspec.
bladder (urinary)C67.9C79.11D09.0D30.3D41.4D49.4
bladder (urinary) › domeC67.1C79.11D09.0D30.3D41.4D49.4
bladder (urinary) › neckC67.5C79.11D09.0D30.3D41.4D49.4
bladder (urinary) › orificeC67.9C79.11D09.0D30.3D41.4D49.4
bladder (urinary) › orifice › uretericC67.6C79.11D09.0D30.3D41.4D49.4
bladder (urinary) › orifice › urethralC67.5C79.11D09.0D30.3D41.4D49.4
bladder (urinary) › sphincterC67.8C79.11D09.0D30.3D41.4D49.4
bladder (urinary) › trigoneC67.0C79.11D09.0D30.3D41.4D49.4
bladder (urinary) › urachusC67.7C79.11D09.0D30.3D41.4D49.4
bladder (urinary) › wallC67.9C79.11D09.0D30.3D41.4D49.4
bladder (urinary) › wall › anteriorC67.3C79.11D09.0D30.3D41.4D49.4
bladder (urinary) › wall › lateralC67.2C79.11D09.0D30.3D41.4D49.4
bladder (urinary) › wall › posteriorC67.4C79.11D09.0D30.3D41.4D49.4
urachusC67.7C79.11D09.0D30.3D41.4D49.4
ureter, ureteral › orifice (bladder)C67.6C79.11D09.0D30.3D41.4D49.4
ureter-bladder (junction)C67.6C79.11D09.0D30.3D41.4D49.4
urethra, urethral (gland) › orifice, internalC67.5C79.11D09.0D30.3D41.4D49.4

Patient EducationClinical

Bladder Diseases

The bladder is a hollow organ in your lower abdomen that stores urine. Many conditions can affect your bladder. Some common ones are:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D49.4 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
239.4 Bladder neoplasm NOS
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About D49.4Overview

What is the ICD-10 code for neoplasm of unspecified behavior of bladder?

The ICD-10-CM code for neoplasm of unspecified behavior of bladder is D49.4 (sometimes written as D494). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is D49.4 (Neoplasms of unspecified behavior) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report neoplasm of unspecified behavior of bladder on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does D49.4 group to?

When neoplasm of unspecified behavior of bladder is the principal diagnosis on an inpatient stay, it groups to MS-DRG 656, 687, 658, 657, 686, 688, with relative weights from 0.7332 to 3.2782 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of D49.4?

Under the General Equivalence Mappings, neoplasm of unspecified behavior of bladder converts to ICD-9-CM 239.4 (bladder neoplasm NOS). The mapping is a direct match.