2026 ICD-10-CM Diagnosis Code D49.4Neoplasm of unspecified behavior of bladder

ICD-10-CM Codes›D50–D89›D49›D49

ICD-10-CM D49.4
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D49.4 is a billable ICD-10-CM diagnosis code for neoplasm of unspecified behavior of bladder. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 656 through 658, 686 through 688. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Neoplasms of unspecified nature or uncertain behavior.

Code Identity

ICD-10-CM Code
D49.4
Billable Status
Yes — Valid for Submission
Code Describes
Neoplasm of unspecified behavior of bladder
Short Description
Neoplasm of unspecified behavior of bladder
Same as the full description in the CMS dataset.
Parent Code
D49
Neoplasms of unspecified behavior

Code Classification

ChapterD50–D89Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
SectionD49Neoplasms of unspecified behavior
CategoryD49Neoplasms of unspecified behavior
This CodeD49.4Neoplasm of unspecified behavior of bladder

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Neoplasm of anterior wall of urinary bladder
  • Neoplasm of apex of urinary bladder
  • Neoplasm of dome of urinary bladder
  • Neoplasm of lateral wall of urinary bladder
  • Neoplasm of neck of urinary bladder
  • Neoplasm of posterior wall of urinary bladder
  • Neoplasm of trigone of urinary bladder
  • Neoplasm of urachus
  • Neoplasm of ureteric orifice of urinary bladder
  • Neoplasm of urinary bladder
  • Neoplasm of urinary bladder neck

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NEO072
Neoplasms of unspecified nature or uncertain behavior
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Urachus

    an embryonic structure originating from the allantois. it is a canal connecting the fetal urinary bladder and the umbilicus. it is normally converted into a fibrous cord postnatally. when the canal fails to be filled and remains open (patent urachus), urine leaks through the umbilicus.

Table of NeoplasmsClinical

Anatomical sites in the Table of Neoplasms that reference this code family.

SiteMalig.
Primary		Malig.
Secondary		Ca
in situ		BenignUncertainUnspec.
bladder (urinary)C67.9C79.11D09.0D30.3D41.4D49.4
bladder (urinary) › domeC67.1C79.11D09.0D30.3D41.4D49.4
bladder (urinary) › neckC67.5C79.11D09.0D30.3D41.4D49.4
bladder (urinary) › orificeC67.9C79.11D09.0D30.3D41.4D49.4
bladder (urinary) › orifice › uretericC67.6C79.11D09.0D30.3D41.4D49.4
bladder (urinary) › orifice › urethralC67.5C79.11D09.0D30.3D41.4D49.4
bladder (urinary) › sphincterC67.8C79.11D09.0D30.3D41.4D49.4
bladder (urinary) › trigoneC67.0C79.11D09.0D30.3D41.4D49.4
bladder (urinary) › urachusC67.7C79.11D09.0D30.3D41.4D49.4
bladder (urinary) › wallC67.9C79.11D09.0D30.3D41.4D49.4
bladder (urinary) › wall › anteriorC67.3C79.11D09.0D30.3D41.4D49.4
bladder (urinary) › wall › lateralC67.2C79.11D09.0D30.3D41.4D49.4
bladder (urinary) › wall › posteriorC67.4C79.11D09.0D30.3D41.4D49.4
urachusC67.7C79.11D09.0D30.3D41.4D49.4
ureter, ureteral › orifice (bladder)C67.6C79.11D09.0D30.3D41.4D49.4
ureter-bladder (junction)C67.6C79.11D09.0D30.3D41.4D49.4
urethra, urethral (gland) › orifice, internalC67.5C79.11D09.0D30.3D41.4D49.4

Patient EducationClinical

Bladder Diseases

The bladder is a hollow organ in your lower abdomen that stores urine. Many conditions can affect your bladder. Some common ones are:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D49.4 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
239.4 Bladder neoplasm NOS
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D49.4Overview

Is D49.4 (Neoplasms of unspecified behavior) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report neoplasm of unspecified behavior of bladder on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does D49.4 group to?

When neoplasm of unspecified behavior of bladder is the principal diagnosis on an inpatient stay, it groups to MS-DRG 656, 657, 658, 686, 687, 688, with relative weights from 0.7903 to 3.1838 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of D49.4?

Under the General Equivalence Mappings, neoplasm of unspecified behavior of bladder converts to ICD-9-CM 239.4 (bladder neoplasm NOS). The mapping is a direct match.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.