2026 ICD-10-CM Diagnosis Code D35.00Benign neoplasm of unspecified adrenal gland

ICD-10-CM Codes›C00–D49›D10-D36›D35

ICD-10-CM D35.00
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D35.00 is a billable ICD-10-CM diagnosis code for benign neoplasm of unspecified adrenal gland. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 643 through 645. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Benign neoplasms.

Code Identity

ICD-10-CM Code
D35.00
Billable Status
Yes — Valid for Submission
Code Describes
Benign neoplasm of unspecified adrenal gland
Short Description
Benign neoplasm of unspecified adrenal gland
Same as the full description in the CMS dataset.
Parent Code
D35.0
Benign neoplasm of adrenal gland

Code Classification

ChapterC00–D49Neoplasms
SectionD10-D36Benign neoplasms, except benign neuroendocrine tumors
CategoryD35Benign neoplasm of other and unspecified endocrine glands
This CodeD35.00Benign neoplasm of unspecified adrenal gland

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Adrenal adenoma
  • Adrenal cortical adenoma
  • Adrenal Cushing's syndrome
  • Aldosterone-producing adenoma
  • Benign neoplasm of adrenal cortex
  • Benign neoplasm of adrenal gland
  • Benign neoplasm of adrenal medulla
  • Benign pheochromocytoma
  • Cushing syndrome due to cortisol-producing adrenocortical adenoma
  • Hereditary pheochromocytoma and paraganglioma
  • Hyperaldosteronism due to neoplasm of the adrenal cortex
  • Hypercortisolism due to adrenal neoplasm
  • Hypermelanosis due to neoplasia
  • Hypermelanosis due to pheochromocytoma
  • Myelolipoma of adrenal gland
  • Paraganglioma
  • Pheochromocytoma
  • Pheochromocytoma crisis
  • Primary hyperaldosteronism due to adrenal adenoma
  • Sporadic pheochromocytoma and secreting paraganglioma
  • Tremor due to pheochromocytoma

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Adenoma
      • adrenal (cortical)
    • Adenoma
      • adrenal (cortical)
        • clear cell
    • Adenoma
      • adrenal (cortical)
        • compact cell
    • Adenoma
      • adrenal (cortical)
        • glomerulosa cell
    • Adenoma
      • adrenal (cortical)
        • heavily pigmented variant
    • Adenoma
      • adrenal (cortical)
        • mixed cell
    • Adenoma
      • black
    • Pheochromocytoma
      • unspecified site

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NEO073
Benign neoplasms
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Carotid Body Tumor

    benign paraganglioma at the bifurcation of the common carotid arteries. it can encroach on the parapharyngeal space and produce dysphagia, pain, and cranial nerve palsies.

  • Glomus Jugulare Tumor

    a paraganglioma involving the glomus jugulare, a microscopic collection of chemoreceptor tissue in the adventitia of the bulb of the jugular vein. it may cause paralysis of the vocal cords, attacks of dizziness, blackouts, and nystagmus. it is not resectable but radiation therapy is effective. it regresses slowly, but permanent control is regularly achieved. (from dorland, 27th ed; stedman, 25th ed; devita jr et al., cancer: principles & practice of oncology, 3d ed, pp1603-4)

  • Paraganglioma

    a neural crest tumor usually derived from the chromoreceptor tissue of a paraganglion, such as the carotid body, or medulla of the adrenal gland (usually called a chromaffinoma or pheochromocytoma). it is more common in women than in men. (stedman, 25th ed; from segen, dictionary of modern medicine, 1992)

  • Paraganglioma, Extra-Adrenal

    a relatively rare, usually benign neoplasm originating in the chemoreceptor tissue of the carotid body; glomus jugulare; glomus tympanicum; aortic bodies; and the female genital tract. it consists histologically of rounded or ovoid hyperchromatic cells that tend to be grouped in an alveolus-like pattern within a scant to moderate amount of fibrous stroma and a few large thin-walled vascular channels. (from stedman, 27th ed)

  • Multiple Endocrine Neoplasia Type 2a

    a form of multiple endocrine neoplasia characterized by the presence of medullary carcinoma (carcinoma, medullary) of the thyroid gland, and usually with the co-occurrence of pheochromocytoma, producing calcitonin and adrenaline, respectively. less frequently, it can occur with hyperplasia or adenoma of the parathyroid glands. this disease is due to gain-of-function mutations of the men2 gene on chromosome 10 (locus: 10q11.2), also known as the ret proto-oncogene that encodes a receptor protein-tyrosine kinase. it is an autosomal dominant inherited disease.

  • PC12 Cells

    a cell line derived from a pheochromocytoma of the rat adrenal medulla. pc12 cells stop dividing and undergo terminal differentiation when treated with nerve growth factor, making the line a useful model system for nerve cell differentiation.

  • Pheochromocytoma

    a usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the adrenal medulla or sympathetic paraganglia. the cardinal symptom, reflecting the increased secretion of epinephrine and norepinephrine, is hypertension, which may be persistent or intermittent. during severe attacks, there may be headache; sweating, palpitation, apprehension, tremor; pallor or flushing of the face, nausea and vomiting, pain in the chest and abdomen, and paresthesias of the extremities. the incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (dorland, 27th ed; devita jr et al., cancer: principles & practice of oncology, 3d ed, p1298)

  • Carotid Artery, Common

    the two principal arteries supplying the structures of the head and neck. they ascend in the neck, one on each side, and at the level of the upper border of the thyroid cartilage, each divides into two branches, the external (carotid artery, external) and internal (carotid artery, internal) carotid arteries.

Table of NeoplasmsClinical

Anatomical sites in the Table of Neoplasms that reference this code family.

SiteMalig.
Primary		Malig.
Secondary		Ca
in situ		BenignUncertainUnspec.
adrenalC74.9C79.7D09.3D35.0D44.1D49.7
adrenal › capsuleC74.9C79.7D09.3D35.0D44.1D49.7
adrenal › cortexC74.0C79.7D09.3D35.0D44.1D49.7
adrenal › glandC74.9C79.7D09.3D35.0D44.1D49.7
adrenal › medullaC74.1C79.7D09.3D35.0D44.1D49.7
cortexC74.0C79.7D09.3D35.0D44.1D49.7
cortex › adrenalC74.0C79.7D09.3D35.0D44.1D49.7
medullaC74.1C79.7D09.3D35.0D44.1D49.7
medulla › adrenalC74.1C79.7D09.3D35.0D44.1D49.7
suprarenalC74.9C79.7D09.3D35.0D44.1D49.7
suprarenal › capsuleC74.9C79.7D09.3D35.0D44.1D49.7
suprarenal › cortexC74.0C79.7D09.3D35.0D44.1D49.7
suprarenal › glandC74.9C79.7D09.3D35.0D44.1D49.7
suprarenal › medullaC74.1C79.7D09.3D35.0D44.1D49.7

Patient EducationClinical

Adrenal Gland Disorders

Your adrenal glands are two small organs that sit on top of each kidney. The adrenal glands make different types of hormones you need to stay alive and healthy. Hormones are chemicals that travel in your bloodstream and control how different parts of your body work.

The full article covers:

  • What are adrenal glands?
  • What are adrenal gland disorders?
  • What causes adrenal gland disorders?
  • How are adrenal gland disorders diagnosed?
  • What are the treatments for adrenal gland disorders?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D35.00 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
227.0 Benign neoplasm adrenal
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D35.00Overview

Is D35.00 (Benign neoplasm of adrenal gland) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report benign neoplasm of unspecified adrenal gland on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does D35.00 group to?

When benign neoplasm of unspecified adrenal gland is the principal diagnosis on an inpatient stay, it groups to MS-DRG 643, 644, 645, with relative weights from 0.7683 to 1.6461 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of D35.00?

Under the General Equivalence Mappings, benign neoplasm of unspecified adrenal gland converts to ICD-9-CM 227.0 (benign neoplasm adrenal). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.