2027 ICD-10-CM Diagnosis Code D35.00Benign neoplasm of unspecified adrenal gland

ICD-10-CM Codes›C00–D49›D10-D36›D35

ICD-10-CM D35.00
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

D35.00 is a billable ICD-10-CM diagnosis code for benign neoplasm of unspecified adrenal gland. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 643 through 645. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Benign neoplasms.

Code Identity

ICD-10-CM Code
D35.00
Billable Status
Yes — Valid for Submission
Code Describes
Benign neoplasm of unspecified adrenal gland
Short Description
Benign neoplasm of unspecified adrenal gland
Same as the full description in the CMS dataset.
Parent Code
Benign neoplasm of adrenal gland

Code Classification

ChapterC00–D49Neoplasms
SectionD10-D36Benign neoplasms, except benign neuroendocrine tumors
CategoryD35Benign neoplasm of other and unspecified endocrine glands
This CodeD35.00Benign neoplasm of unspecified adrenal gland

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Adrenal adenoma
  • Adrenal cortical adenoma
  • Adrenal Cushing's syndrome
  • Aldosterone-producing adenoma
  • Benign neoplasm of adrenal cortex
  • Benign neoplasm of adrenal gland
  • Benign neoplasm of adrenal medulla
  • Benign pheochromocytoma
  • Cushing syndrome due to cortisol-producing adrenocortical adenoma
  • Hereditary pheochromocytoma and paraganglioma
  • Hyperaldosteronism due to neoplasm of the adrenal cortex
  • Hypercortisolism due to adrenal neoplasm
  • Hypermelanosis due to neoplasia
  • Hypermelanosis due to pheochromocytoma
  • Hypertension due to pheochromocytoma
  • Myelolipoma of adrenal gland
  • Paraganglioma
  • Pheochromocytoma
  • Pheochromocytoma crisis
  • Primary hyperaldosteronism due to adrenal adenoma
  • Sporadic pheochromocytoma and secreting paraganglioma
  • Tremor due to pheochromocytoma

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to D35.00: its own notes plus those printed at D35 and Chapter 2. A note printed at a category, block or chapter applies to every code under it.

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From D35 Benign neoplasm of other and unspecified endocrine glands applies to 11 codes
  • benign neoplasm of endocrine pancreas (D13.7)
  • benign neoplasm of ovary (D27.-)
  • benign neoplasm of testis (D29.2.-)
  • benign neoplasm of thymus (D15.0)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

From D35 Benign neoplasm of other and unspecified endocrine glands applies to 11 codes
  • code to identify any functional activity

Notes

General instructions on how these codes are used.

From Chapter 2 (C00-D49) Neoplasms applies to 1,730 codes
  • Functional activity
  • All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
  • Morphology [Histology]
  • Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
  • Primary malignant neoplasms overlapping site boundaries
  • A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
  • Malignant neoplasm of ectopic tissue
  • Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name D35.00, its category, or a range that includes it.

Code Also 2

These codes say D35.00 may also be needed to fully describe the condition. The note gives no sequencing direction.

  • E26.01 Conn's syndrome
    adrenal adenoma (D35.0-) names D35.0-, which includes this code
  • E27.5 Adrenomedullary hyperfunction
    pheochromocytoma (benign) (D35.0-) names D35.0-, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NEO073
Benign neoplasms
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Benign Adrenal Gland Neoplasm

    a neoplasm that arises from the adrenal gland and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential.

Table of NeoplasmsClinical

Anatomical sites in the Table of Neoplasms that reference this code family.

SiteMalig.
Primary
Malig.
Secondary
Ca
in situ
BenignUncertainUnspec.
adrenalC74.9C79.7D09.3D35.0D44.1D49.7
adrenal › capsuleC74.9C79.7D09.3D35.0D44.1D49.7
adrenal › cortexC74.0C79.7D09.3D35.0D44.1D49.7
adrenal › glandC74.9C79.7D09.3D35.0D44.1D49.7
adrenal › medullaC74.1C79.7D09.3D35.0D44.1D49.7
cortex › adrenalC74.0C79.7D09.3D35.0D44.1D49.7
medulla › adrenalC74.1C79.7D09.3D35.0D44.1D49.7
suprarenalC74.9C79.7D09.3D35.0D44.1D49.7
suprarenal › capsuleC74.9C79.7D09.3D35.0D44.1D49.7
suprarenal › cortexC74.0C79.7D09.3D35.0D44.1D49.7
suprarenal › glandC74.9C79.7D09.3D35.0D44.1D49.7
suprarenal › medullaC74.1C79.7D09.3D35.0D44.1D49.7

Patient EducationClinical

Adrenal Gland Disorders

Your adrenal glands are two small organs that sit on top of each kidney. The adrenal glands make different types of hormones you need to stay alive and healthy. Hormones are chemicals that travel in your bloodstream and control how different parts of your body work.

The full article covers:

  • What are adrenal glands?
  • What are adrenal gland disorders?
  • What causes adrenal gland disorders?
  • How are adrenal gland disorders diagnosed?
  • What are the treatments for adrenal gland disorders?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D35.00 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
227.0 Benign neoplasm adrenal
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About D35.00Overview

What is the ICD-10 code for benign neoplasm of unspecified adrenal gland?

The ICD-10-CM code for benign neoplasm of unspecified adrenal gland is D35.00 (sometimes written as D3500). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is D35.00 (Benign neoplasm of adrenal gland) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report benign neoplasm of unspecified adrenal gland on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does D35.00 group to?

When benign neoplasm of unspecified adrenal gland is the principal diagnosis on an inpatient stay, it groups to MS-DRG 644, 645, 643, with relative weights from 0.7461 to 1.6138 depending on complications. Higher weights mean higher Medicare reimbursement.

Can D35.00 be reported with D13.7?

Not as a rule. The Excludes1 note at D35, which applies to D35.00, lists "benign neoplasm of endocrine pancreas (D13.7)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

Does D35.00 need an additional code?

When the condition applies, yes. The Use Additional Code note at D35, which applies to D35.00, reads: code to identify any functional activity. The additional code is reported after D35.00.