2026 ICD-10-CM Diagnosis Code D33.0Benign neoplasm of brain, supratentorial

ICD-10-CM CodesC00–D49D10-D36D33

ICD-10-CM D33.0
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D33.0 is a billable ICD-10-CM diagnosis code for benign neoplasm of brain, supratentorial. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Benign neoplasms.

Code Identity

ICD-10-CM Code
D33.0
Billable Status
Yes — Valid for Submission
Code Describes
Benign neoplasm of brain, supratentorial
Short Description
Benign neoplasm of brain, supratentorial
Same as the full description in the CMS dataset.
Parent Code
Benign neoplasm of brain and other parts of central nervous system

Code Classification

ChapterC00–D49Neoplasms
SectionD10-D36Benign neoplasms, except benign neuroendocrine tumors
CategoryD33Benign neoplasm of brain and other parts of central nervous system
This CodeD33.0Benign neoplasm of brain, supratentorial

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Benign neoplasm of brain, supratentorial
  • Benign neoplasm of cerebrum
  • Benign neoplasm of choroid plexus
  • Benign neoplasm of frontal lobe
  • Benign neoplasm of hypothalamus
  • Benign neoplasm of occipital lobe
  • Benign neoplasm of parietal lobe
  • Benign neoplasm of temporal lobe
  • Benign neoplasm of ventricle of brain
  • Benign papilloma of choroid plexus
  • Dysembryoplastic neuroepithelial tumor
  • Hamartoma of brain
  • Hamartoma of hypothalamus
  • Hamartoma of pituitary and hypothalamus
  • Hypothalamic neuronal hamartoma
  • Increased cerebrospinal fluid production
  • Increased cerebrospinal fluid production due to benign papilloma of choroid plexus
  • Neoplasm of choroid plexus
  • Neoplasm of hypothalamus

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Benign neoplasm of cerebral ventricle
  • Benign neoplasm of cerebrum
  • Benign neoplasm of frontal lobe
  • Benign neoplasm of occipital lobe
  • Benign neoplasm of parietal lobe
  • Benign neoplasm of temporal lobe

Type 1 Excludes

  • benign neoplasm of fourth ventricle D33.1

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Papilloma
      • choroid plexus (lateral ventricle) (third ventricle)

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NEO073
Benign neoplasms
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Basal Ganglia

    large subcortical nuclear masses derived from the telencephalon and located in the basal regions of the cerebral hemispheres.
  • Basal Ganglia Cerebrovascular Disease

    a pathological condition caused by impaired blood flow in the basal regions of cerebral hemispheres (basal ganglia), such as infarction; hemorrhage; or ischemia in vessels of this brain region including the lateral lenticulostriate arteries. primary clinical manifestations include involuntary movements (dyskinesias) and muscle weakness (hemiparesis).
  • Basal Ganglia Diseases

    diseases of the basal ganglia including the putamen; globus pallidus; claustrum; amygdala; and caudate nucleus. dyskinesias (most notably involuntary movements and alterations of the rate of movement) represent the primary clinical manifestations of these disorders. common etiologies include cerebrovascular disorders; neurodegenerative diseases; and craniocerebral trauma.
  • Basal Ganglia Hemorrhage

    bleeding within the subcortical regions of cerebral hemispheres (basal ganglia). it is often associated with hypertension or arteriovenous malformations. clinical manifestations may include headache; dyskinesias; and hemiparesis.
  • Globus Pallidus

    the representation of the phylogenetically oldest part of the corpus striatum called the paleostriatum. it forms the smaller, more medial part of the lentiform nucleus.
  • Anterior Hypothalamic Nucleus

    loose heterogeneous collection of cells in the anterior hypothalamus, continuous rostrally with the medial and lateral preoptic areas and caudally with the tuber cinereum.
  • Arcuate Nucleus of Hypothalamus

    a nucleus located in the middle hypothalamus in the most ventral part of the third ventricle near the entrance of the infundibular recess. its small cells are in close contact with the ependyma.
  • Hypothalamic Area, Lateral

    area in the hypothalamus bounded medially by the mammillothalamic tract and the anterior column of the fornix (brain). the medial edge of the internal capsule and the subthalamic region form its lateral boundary. it contains the lateral hypothalamic nucleus, tuberomammillary nucleus, lateral tuberal nuclei, and fibers of the medial forebrain bundle.
  • Hypothalamic Neoplasms

    benign and malignant tumors of the hypothalamus. pilocytic astrocytomas and hamartomas are relatively frequent histologic types. neoplasms of the hypothalamus frequently originate from adjacent structures, including the optic chiasm, optic nerve (see optic nerve neoplasms), and pituitary gland (see pituitary neoplasms). relatively frequent clinical manifestations include visual loss, developmental delay, macrocephaly, and precocious puberty. (from devita et al., cancer: principles and practice of oncology, 5th ed, p2051)
  • Hypothalamus

    ventral part of the diencephalon extending from the region of the optic chiasm to the caudal border of the mammillary bodies and forming the inferior and lateral walls of the third ventricle.
  • Hypothalamus, Anterior

    the front portion of the hypothalamus separated into the preoptic region and the supraoptic region. the preoptic region is made up of the periventricular gray matter of the rostral portion of the third ventricle and contains the preoptic ventricular nucleus and the medial preoptic nucleus. the supraoptic region contains the paraventricular hypothalamic nucleus, the supraoptic nucleus, the anterior hypothalamic nucleus, and the suprachiasmatic nucleus.
  • Hypothalamus, Middle

    middle portion of the hypothalamus containing the arcuate, dorsomedial, ventromedial nuclei, the tuber cinereum and the pituitary gland.
  • Hypothalamus, Posterior

    the part of the hypothalamus posterior to the middle region consisting of several nuclei including the medial maxillary nucleus, lateral mammillary nucleus, and posterior hypothalamic nucleus (posterior hypothalamic area). the posterior hypothalamic area is concerned with control of sympathetic responses and is sensitive to conditions of decreasing temperature and controls the mechanisms for the conservation and increased production of heat.
  • Pituitary Gland

    a small, unpaired gland situated in the sella turcica. it is connected to the hypothalamus by a short stalk which is called the infundibulum.
  • Supraoptic Nucleus

    hypothalamic nucleus overlying the beginning of the optic tract.
  • Putamen

    the largest and most lateral of the basal ganglia lying between the lateral medullary lamina of the globus pallidus and the external capsule. it is part of the neostriatum and forms part of the lentiform nucleus along with the globus pallidus.
  • Putaminal Hemorrhage

    intracranial bleeding into the putamen, a basal ganglia nucleus. this is associated with hypertension and lipohyalinosis of small blood vessels in the putamen. clinical manifestations vary with the size of hemorrhage, but include hemiparesis; headache; and alterations of consciousness.
  • Anterior Thalamic Nuclei

    three nuclei located beneath the dorsal surface of the most rostral part of the thalamus. the group includes the anterodorsal nucleus, anteromedial nucleus, and anteroventral nucleus. all receive connections from the mamillary body and brain fornix, and project fibers to the cingulate body.
  • Intralaminar Thalamic Nuclei

    cell groups within the internal medullary lamina of the thalamus. they include a rostral division comprising the paracentral, central lateral, central dorsal, and central medial nuclei, and a caudal division composed of the centromedian and parafascicular nuclei.
  • Mediodorsal Thalamic Nucleus

    the largest of the medial nuclei of the thalamus. it makes extensive connections with most of the other thalamic nuclei.
  • Midline Thalamic Nuclei

    small, nonspecific nerve cells scattered in the periventricular gray matter, separating the medial part of the thalamus from the ependyma of the third ventricle. the group includes the paraventricular nucleus, paratenial nucleus, reuniens nucleus, rhomboidal nucleus, and subfascular nucleus.
  • Posterior Thalamic Nuclei

    a transitional diencephalic zone of the thalamus consisting of complex and varied cells lying caudal to the ventral posterolateral nucleus, medial to the rostral part of the pulvinar, and dorsal to the medial geniculate body. it contains the limitans, posterior, suprageniculate, and submedial nuclei.
  • Pulvinar

    large mass of nuclei forming the most caudal portion of the thalamus and overhanging the geniculate bodies and the dorsolateral surface of the midbrain. it is divided into four parts: the lateral, medial, inferior, and oral pulvinar nuclei.
  • Thalamus

    paired bodies containing mostly gray matter and forming part of the lateral wall of the third ventricle of the brain.
  • Ventral Thalamic Nuclei

    a large group of nuclei lying between the internal medullary lamina and the internal capsule. it includes the ventral anterior, ventral lateral, and ventral posterior nuclei.

Table of NeoplasmsClinical

Anatomical sites in the Table of Neoplasms that reference this code family.

SiteMalig.
Primary
Malig.
Secondary
Ca
in situ
BenignUncertainUnspec.
basal gangliaC71.0C79.31D33.0D43.0D49.6
brain NEC basal gangliaC71.0C79.31D33.0D43.0D49.6
brain NEC cerebrumC71.0C79.31D33.0D43.0D49.6
brain NEC corpus striatumC71.0C79.31D33.0D43.0D49.6
brain NEC cortex (cerebral)C71.0C79.31D33.0D43.0D49.6
brain NEC frontal lobeC71.1C79.31D33.0D43.0D49.6
brain NEC globus pallidusC71.0C79.31D33.0D43.0D49.6
brain NEC hippocampusC71.2C79.31D33.0D43.0D49.6
brain NEC hypothalamusC71.0C79.31D33.0D43.0D49.6
brain NEC internal capsuleC71.0C79.31D33.0D43.0D49.6
brain NEC occipital lobeC71.4C79.31D33.0D43.0D49.6
brain NEC parietal lobeC71.3C79.31D33.0D43.0D49.6
brain NEC temporal lobeC71.2C79.31D33.0D43.0D49.6
brain NEC thalamusC71.0C79.31D33.0D43.0D49.6
brain NEC uncusC71.2C79.31D33.0D43.0D49.6
brain NEC ventricle (floor)C71.5C79.31D33.0D43.0D49.6
cerebrum, cerebral (cortex) (hemisphere) (white matter)C71.0C79.31D33.0D43.0D49.6
cerebrum, cerebral (cortex) (hemisphere) (white matter) ventricleC71.5C79.31D33.0D43.0D49.6
choroid plexusC71.5C79.31D33.0D43.0D49.6
corpus striatum, cerebrumC71.0C79.31D33.0D43.0D49.6
cortex cerebralC71.0C79.31D33.0D43.0D49.6
ependyma (brain)C71.5C79.31D33.0D43.0D49.6
frontal lobe, brainC71.1C79.31D33.0D43.0D49.6
frontal poleC71.1C79.31D33.0D43.0D49.6
ganglia [See Also: Neoplasm, nerve, peripheral] basalC71.0C79.31D33.0D43.0D49.6
globus pallidusC71.0C79.31D33.0D43.0D49.6
hemisphere, cerebralC71.0C79.31D33.0D43.0D49.6
hippocampus, brainC71.2C79.31D33.0D43.0D49.6
hypothalamusC71.0C79.31D33.0D43.0D49.6
insulaC71.0C79.31D33.0D43.0D49.6
insular tissue (pancreas) brainC71.0C79.31D33.0D43.0D49.6
internalC71.0C79.31D33.0D43.0D49.6
internal capsuleC71.0C79.31D33.0D43.0D49.6
island of ReilC71.0C79.31D33.0D43.0D49.6
occipital lobe or pole, brainC71.4C79.31D33.0D43.0D49.6
operculum (brain)C71.0C79.31D33.0D43.0D49.6
palliumC71.0C79.31D33.0D43.0D49.6
parietal lobe, brainC71.3C79.31D33.0D43.0D49.6
plexus choroidC71.5C79.31D33.0D43.0D49.6
poleC71.1C79.31D33.0D43.0D49.6
pole frontalC71.1C79.31D33.0D43.0D49.6
pole occipitalC71.4C79.31D33.0D43.0D49.6
putamenC71.0C79.31D33.0D43.0D49.6
rhinencephalonC71.0C79.31D33.0D43.0D49.6
supratentorial (brain) NECC71.0C79.31D33.0D43.0D49.6
temporal lobe or poleC71.2C79.31D33.0D43.0D49.6
thalamusC71.0C79.31D33.0D43.0D49.6
uncus, brainC71.2C79.31D33.0D43.0D49.6
ventricle (cerebral) (floor) (lateral) (third)C71.5C79.31D33.0D43.0D49.6
white matter (central) (cerebral)C71.0C79.31D33.0D43.0D49.6

Patient EducationClinical

Benign Tumors

Tumors are abnormal growths in your body. They can be either benign or malignant. Benign tumors aren't cancer. Malignant ones are. Benign tumors grow only in one place. They cannot spread or invade other parts of your body. Even so, they can be dangerous if they press on vital organs, such as your brain.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D33.0 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
225.0 Benign neoplasm brain
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D33.0Overview

Is D33.0 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report benign neoplasm of brain, supratentorial on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What is the ICD-9 equivalent of D33.0?

Under the General Equivalence Mappings, benign neoplasm of brain, supratentorial converts to ICD-9-CM 225.0 (benign neoplasm brain). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.