2027 ICD-10-CM Diagnosis Code D25.1Intramural leiomyoma of uterus

ICD-10-CM Codes›C00–D49›D10-D36›D25

ICD-10-CM D25.1
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

D25.1 is a billable ICD-10-CM diagnosis code for intramural leiomyoma of uterus. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 742 through 743, 760 through 761. Coders also document this condition as abnormal uterine bleeding due to intramural uterine fibroid. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Benign neoplasms.

Code Identity

ICD-10-CM Code
D25.1
Billable Status
Yes — Valid for Submission
Code Describes
Intramural leiomyoma of uterus
Short Description
Intramural leiomyoma of uterus
Same as the full description in the CMS dataset.
Parent Code
Leiomyoma of uterus

Code Classification

ChapterC00–D49Neoplasms
SectionD10-D36Benign neoplasms, except benign neuroendocrine tumors
CategoryD25Leiomyoma of uterus
This CodeD25.1Intramural leiomyoma of uterus

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Abnormal uterine bleeding due to intramural uterine fibroid
  • Abnormal uterine bleeding due to uterine fibroid
  • Benign neoplasm of body of uterus
  • Benign neoplasm of myometrium
  • Intramural leiomyoma of uterus

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to D25.1: its own notes plus those printed at D25 and Chapter 2. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From D25 Leiomyoma of uterus applies to 4 codes
  • uterine fibroid
  • uterine fibromyoma
  • uterine myoma

Applicable To

Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.

  • Interstitial leiomyoma of uterus

Notes

General instructions on how these codes are used.

From Chapter 2 (C00-D49) Neoplasms applies to 1,730 codes
  • Functional activity
  • All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
  • Morphology [Histology]
  • Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
  • Primary malignant neoplasms overlapping site boundaries
  • A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
  • Malignant neoplasm of ectopic tissue
  • Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name D25.1, its category, or a range that includes it.

Excludes1 2

These codes carry an Excludes1 note naming D25.1: they are not reported together with it, unless the two conditions are unrelated.

  • D21 Other benign neoplasms of connective and other soft tissue
    uterine leiomyoma (D25.-) names D25.-, which includes this code
  • D21.5 Benign neoplasm of connective and other soft tissue of pelvis
    uterine leiomyoma (D25.-) names D25.-, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NEO073
Benign neoplasms
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Uterine Fibroids

Uterine fibroids are the most common noncancerous (benign) tumors in women of childbearing age. You may have uterine fibroids and not even know it since they often don't cause any symptoms. Fibroids are made of muscle cells and other tissues that grow in and around the wall of the uterus, or womb.

The full article covers:

  • What are uterine fibroids?
  • Who is more likely to get uterine fibroids?
  • What causes uterine fibroids?
  • What are the symptoms of uterine fibroids?
  • How are uterine fibroids diagnosed?
  • What are the treatments for uterine fibroids?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D25.1 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
218.1 Intramural leiomyoma
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About D25.1Overview

What is the ICD-10 code for intramural leiomyoma of uterus?

The ICD-10-CM code for intramural leiomyoma of uterus is D25.1 (sometimes written as D251). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is D25.1 (Leiomyoma of uterus) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report intramural leiomyoma of uterus on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does D25.1 group to?

When intramural leiomyoma of uterus is the principal diagnosis on an inpatient stay, it groups to MS-DRG 742, 743, 760, 761, with relative weights from 0.7039 to 1.8448 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of D25.1?

Under the General Equivalence Mappings, intramural leiomyoma of uterus converts to ICD-9-CM 218.1 (intramural leiomyoma). The mapping is a direct match.