2026 ICD-10-CM Diagnosis Code D22.121Melanocytic nevi of left upper eyelid, including canthus

ICD-10-CM Codes›C00–D49›D10-D36›D22

ICD-10-CM D22.121
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D22.121 is a billable ICD-10-CM diagnosis code for melanocytic nevi of left upper eyelid, including canthus. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 124 through 125. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Benign neoplasms.

Code Identity

ICD-10-CM Code
D22.121
Billable Status
Yes — Valid for Submission
Code Describes
Melanocytic nevi of left upper eyelid, including canthus
Short Description
Melanocytic nevi of left upper eyelid, including canthus
Same as the full description in the CMS dataset.
Parent Code
D22.12
Melanocytic nevi of left eyelid, including canthus

Code Classification

ChapterC00–D49Neoplasms
SectionD10-D36Benign neoplasms, except benign neuroendocrine tumors
CategoryD22Melanocytic nevi
This CodeD22.121Melanocytic nevi of left upper eyelid, including canthus

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Benign neoplasm of skin of left upper eyelid
  • Congenital melanocytic nevus of face
  • Congenital melanocytic nevus of skin of left upper eyelid
  • Congenital melanocytic nevus of skin of upper eyelid
  • Epidermal nevus of left upper eyelid
  • Hyperpigmentation of eyelid
  • Hyperpigmentation of left eyelid and periocular area
  • Melanocytic nevus of left upper eyelid
  • Melanocytic nevus of upper eyelid
  • Pigmented hairy epidermal nevus of face
  • Pigmented hairy epidermal nevus of left upper eyelid
  • Pigmented hairy epidermal nevus of upper eyelid

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NEO073
Benign neoplasms
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Birthmarks

Birthmarks are abnormalities of the skin that are present when a baby is born. There are two types of birthmarks. Vascular birthmarks are made up of blood vessels that haven't formed correctly. They are usually red. Two types of vascular birthmarks are hemangiomas and port-wine stains.

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Code History & ChangesHistory

Replacement D22.121 replaces the following previously assigned code(s):

  • D22.12 - Melanocytic nevi of left eyelid, including canthus
FY 2019AddedAdded to the ICD-10-CM code setEffective October 1, 2018.
FY 2020–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D22.121Overview

Is D22.121 (Melanocytic nevi of left eyelid, including canthus) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report melanocytic nevi of left upper eyelid, including canthus on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does D22.121 group to?

When melanocytic nevi of left upper eyelid, including canthus is the principal diagnosis on an inpatient stay, it groups to MS-DRG 124, 125, with relative weights from 0.7678 to 1.3231 depending on complications. Higher weights mean higher Medicare reimbursement.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.