2026 ICD-10-CM Diagnosis Code D12.6Benign neoplasm of colon, unspecified

ICD-10-CM CodesC00–D49D10-D36D12

ICD-10-CM D12.6
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D12.6 is a billable ICD-10-CM diagnosis code for benign neoplasm of colon, unspecified. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 393 through 395. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Benign neoplasms.

Code Identity

ICD-10-CM Code
D12.6
Billable Status
Yes — Valid for Submission
Code Describes
Benign neoplasm of colon, unspecified
Short Description
Benign neoplasm of colon, unspecified
Same as the full description in the CMS dataset.
Parent Code
Benign neoplasm of colon, rectum, anus and anal canal

Code Classification

ChapterC00–D49Neoplasms
SectionD10-D36Benign neoplasms, except benign neuroendocrine tumors
CategoryD12Benign neoplasm of colon, rectum, anus and anal canal
This CodeD12.6Benign neoplasm of colon, unspecified

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Adenoma of large intestine
  • Adenomatous polyp of colon
  • Attenuated familial adenomatous polyposis
  • Benign epithelial neoplasm of large intestine
  • Benign gastrointestinal stromal neoplasm of large intestine
  • Benign lymphoid polyposis of intestine
  • Benign mesenchymoma of large intestine
  • Benign neoplasm of colon
  • Benign neoplasm of large intestine
  • Benign neoplasm of large intestine with hemorrhage
  • Benign polyp of colon
  • Benign stromal neoplasm of gastrointestinal tract
  • Benign tubular adenoma of large intestine
  • Cap polyposis
  • Dysplasia of colon
  • Dysplasia of large intestine
  • Familial adenomatous polyposis due to 5q22.2 microdeletion
  • Familial multiple polyposis syndrome
  • Gardner syndrome
  • Gastrointestinal stromal tumor of large intestine
  • Hamartoma of intestine
  • Hereditary mixed polyposis syndrome
  • Inflammatory polyposis of intestine
  • Intestinal polyposis syndrome
  • Leiomyoma of large intestine
  • Low grade glandular intraepithelial neoplasia of large intestine
  • Malignant neoplasm of intestine due to familial adenomatous polyposis
  • Metaplastic polyposis of intestine
  • Mild dysplasia of colon
  • Moderate dysplasia of colon
  • MYH-associated polyposis
  • Nonfamilial multiple polyposis syndrome
  • Pseudoinvasion in adenomatous polyp of large intestine
  • Pseudopolyposis of colon
  • Serrated polyp of colon
  • Sessile serrated polyp of colon
  • Severe dysplasia of colon
  • Tubular adenoma
  • Tubular adenomatous polyp of colon
  • Tubulovillous adenomatous polyp of colon
  • Turcot syndrome
  • Villous adenomatous polyp of colon

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Adenomatosis of colon
  • Benign neoplasm of large intestine NOS
  • Polyposis (hereditary) of colon

Type 2 Excludes

  • inflammatory polyp of colon K51.4

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Adenomatosis
      • unspecified site
    • Dysplasia
      • colon
    • Dysplasia
      • high grade, focal
    • Polyp, polypus
      • colon
        • adenomatous
    • Polyposis
      • coli
    • Polyposis
      • colon
    • Polyposis
      • familial
    • Polyposis
      • intestinal

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NEO073
Benign neoplasms
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Gardner Syndrome

    a variant of adenomatous polyposis coli caused by mutation in the apc gene (genes, apc) on chromosome 5. it is characterized by not only the presence of multiple colonic polyposis but also extracolonic adenomatous polyps in the upper gastrointestinal tract; the eye; the skin; the skull; and the facial bones; as well as malignancy in organs other than the gi tract.
  • Intestinal Polyposis Syndrome

    a syndrome associated with the development of multiple polyps throughout the intestine. it includes familial adenomatous polyposis , hamartomatous polyposis syndromes, and other rare polyposis syndromes.
  • Turcot Syndrome

    an autosomal dominant hereditary neoplastic syndrome caused by mutations in the pms2, mlh1, msh2, or apc genes. there are two types described, type 1, characterized by the presence of glioblastoma and often associated with hereditary nonpolyposis colorectal carcinoma, and type 2, characterized by the presence of medulloblastoma and familiar adenomatous polyposis.
  • Turcot Syndrome Type 1

    an autosomal dominant hereditary neoplastic syndrome caused by mutations in the pms2, mlh1, or msh2 genes. it is characterized by the presence of glioblastoma and the absence of familiar adenomatous polyposis. patients often develop hereditary nonpolyposis colorectal carcinoma.
  • Turcot Syndrome Type 2

    an autosomal dominant hereditary neoplastic syndrome caused by mutations in the apc gene. it is characterized by the presence of medulloblastoma and familiar adenomatous polyposis.

Table of NeoplasmsClinical

Anatomical sites in the Table of Neoplasms that reference this code family.

SiteMalig.
Primary
Malig.
Secondary
Ca
in situ
BenignUncertainUnspec.
intestine, intestinal largeC18.9C78.5D01.0D12.6D37.4D49.0
intestine, intestinal large colonC18.9C78.5D01.0D12.6D37.4D49.0

Patient EducationClinical

Benign Tumors

Tumors are abnormal growths in your body. They can be either benign or malignant. Benign tumors aren't cancer. Malignant ones are. Benign tumors grow only in one place. They cannot spread or invade other parts of your body. Even so, they can be dangerous if they press on vital organs, such as your brain.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D12.6 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
211.3 Benign neoplasm lg bowel
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D12.6Overview

Is D12.6 (Benign neoplasm of colon, rectum, anus and anal canal) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report benign neoplasm of colon, unspecified on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does D12.6 group to?

When benign neoplasm of colon, unspecified is the principal diagnosis on an inpatient stay, it groups to MS-DRG 393, 394, 395, with relative weights from 0.6490 to 1.5993 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of D12.6?

Under the General Equivalence Mappings, benign neoplasm of colon, unspecified converts to ICD-9-CM 211.3 (benign neoplasm lg bowel). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.