2027 ICD-10-CM Diagnosis Code A88.8Other specified viral infections of central nervous system
ICD-10-CM Codes›A00–B99›A80-A89›A88
- Billable — Valid for Submission
- CC — Complication or Comorbidity
- Not Chronic
A88.8 is a billable ICD-10-CM diagnosis code for other specified viral infections of central nervous system. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 97 through 99, 974 through 976. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 188 closely related codes. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified CNS infection and poliomyelitis and Viral infection.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Cache Valley virus infection
- Coxsackievirus infection of the central nervous system
- Disease caused by Parvoviridae
- Echovirus infection of the central nervous system
- Enteroviral neurological disease
- Epstein Barr virus infection of the central nervous system
- Infection of central nervous system caused by Enterovirus
- Infection of central nervous system caused by Parvovirus
- Influenza with CNS disorder
- Invasive viral infectious disease
- Measles of the central nervous system
- Neuroinvasive Cache Valley virus disease
- Parvovirus infection
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to A88.8: its own notes plus those printed at A88, block A80-A89, and Chapter 1. A note printed at a category, block or chapter applies to every code under it.
Includes
Further defines, or gives examples of, the content of the category.
- diseases generally recognized as communicable or transmissible
Excludes1
Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
- carrier or suspected carrier of infectious disease (Z22.-)
- certain localized infections - see body system-related chapters
- infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium (O98.-)
- infectious and parasitic diseases specific to the perinatal period (P35-P39)
- influenza and other acute respiratory infections (J00-J22)
Use Additional Code
Add a second code, after this one, to fully describe the condition.
- code to identify resistance to antimicrobial drugs (Z16.-)
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Disease, diseased See Also: Syndrome;
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Patient EducationClinical
Neurologic Diseases
The brain, spinal cord, and nerves make up the nervous system. Together they control all the workings of the body. When something goes wrong with a part of your nervous system, you can have trouble moving, speaking, swallowing, breathing, or learning. You can also have problems with your memory, senses, or mood.
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert A88.8 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About A88.8Overview
What is the ICD-10 code for other specified viral infections of central nervous system?
The ICD-10-CM code for other specified viral infections of central nervous system is A88.8 (sometimes written as A888). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is A88.8 a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report other specified viral infections of central nervous system on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does A88.8 group to?
When other specified viral infections of central nervous system is the principal diagnosis on an inpatient stay, it groups to MS-DRG 98, 974, 976, 99, 975, 97, with relative weights from 0.7879 to 3.8208 depending on complications. Higher weights mean higher Medicare reimbursement.
Is A88.8 a CC or MCC?
CMS lists A88.8 as a CC (complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 188 closely related codes in its exclusion list.
Can A88.8 be reported with A86?
Not as a rule. The Excludes1 note at A88, which applies to A88.8, lists "viral encephalitis NOS (A86)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).
