Atypical virus infections of central nervous system (A81)

• ICD-10 Index

  • Certain infectious and parasitic diseases (A00–B99)

    • Viral and prion infections of the central nervous system (A80-A89)

      • Atypical virus infections of central nervous system (A81)

        • A81 - Atypical virus infections of central nervous system NON-BILLABLE CODE
        • A81.0 - Creutzfeldt-Jakob disease NON-BILLABLE CODE
        • A81.00 - Creutzfeldt-Jakob disease, unspecified BILLABLE CODE
        • A81.01 - Variant Creutzfeldt-Jakob disease BILLABLE CODE
        • A81.09 - Other Creutzfeldt-Jakob disease BILLABLE CODE
        • A81.1 - Subacute sclerosing panencephalitis BILLABLE CODE
        • A81.2 - Progressive multifocal leukoencephalopathy BILLABLE CODE
        • A81.8 - Other atypical virus infections of central nervous system NON-BILLABLE CODE
        • A81.81 - Kuru BILLABLE CODE
        • A81.82 - Gerstmann-Straussler-Scheinker syndrome BILLABLE CODE
        • A81.83 - Fatal familial insomnia BILLABLE CODE
        • A81.89 - Other atypical virus infections of central nervous system BILLABLE CODE
        • A81.9 - Atypical virus infection of central nervous system, unsp BILLABLE CODE

Clinical Information for Atypical virus infections of central nervous system (A81)

Kuru - A prion disease found exclusively among the Fore linguistic group natives of the highlands of NEW GUINEA. The illness is primarily restricted to adult females and children of both sexes. It is marked by the subacute onset of tremor and ataxia followed by motor weakness and incontinence. Death occurs within 3-6 months of disease onset. The condition is associated with ritual cannibalism, and has become rare since this practice has been discontinued. Pathologic features include a noninflammatory loss of neurons that is most prominent in the cerebellum, glial proliferation, and amyloid plaques. (From Adams et al., Principles of Neurology, 6th ed, p773)

Subacute Sclerosing Panencephalitis - A rare, slowly progressive encephalitis caused by chronic infection with the MEASLES VIRUS. The condition occurs primarily in children and young adults, approximately 2-8 years after the initial infection. A gradual decline in intellectual abilities and behavioral alterations are followed by progressive MYOCLONUS; MUSCLE SPASTICITY; SEIZURES; DEMENTIA; autonomic dysfunction; and ATAXIA. DEATH usually occurs 1-3 years after disease onset. Pathologic features include perivascular cuffing, eosinophilic cytoplasmic inclusions, neurophagia, and fibrous gliosis. It is caused by the SSPE virus, which is a defective variant of MEASLES VIRUS. (From Adams et al., Principles of Neurology, 6th ed, pp767-8)

New Guinea - Originally an island of the Malay Archipelago, the second largest island in the world. It divided, West New Guinea becoming part of Indonesia and East New Guinea becoming Papua New Guinea.

Instructional Notations

Includes Includes
This note appears immediately under a three character code title to further define, or give examples of, the content of the category.

• diseases of the central nervous system caused by prions

Use Additional Code Use Additional Code
The “use additional code” indicates that a secondary code could be used to further specify the patient’s condition. This note is not mandatory and is only used if enough information is available to assign an additional code.

• code, if applicable, to identify:
• dementia with anxiety F02.84 F02.A4 F02.B4 F02.C4
• dementia with behavioral disturbance F02.81 F02.A1 F02.B1 F02.C1
• dementia with mood disturbance F02.83 F02.A3 F02.B3 F02.C3
• dementia with psychotic disturbance F02.82 F02.A2 F02.B2 F02.C2
• dementia without behavioral disturbance F02.80 F02.A0 F02.B0 F02.C0
• mild neurocognitive disorder due to known physiological condition F06.7