2027 ICD-10-CM Diagnosis Code A42.7Actinomycotic sepsis

ICD-10-CM Codes›A00–B99›A30-A49›A42

ICD-10-CM A42.7
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

A42.7 is a billable ICD-10-CM diagnosis code for actinomycotic sepsis. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 791, 793, 870 through 872, 974 through 976. As a secondary diagnosis, it counts as a major complication or comorbidity (MCC) and places an inpatient stay in the highest severity level of its MS-DRG family. It does not count, however, when the principal diagnosis is one of 46 closely related codes. Coders also document this condition as sepsis caused by Actinomyces. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Bacterial infections and Septicemia.

For Medicare Advantage risk adjustment, A42.7 maps to CMS-HCC Category 2 (Septicemia, Sepsis, Systemic Inflammatory Response Syndrome/Shock) under the V28 model, adding a risk factor of about 0.500 for a community, non-dual, aged beneficiary in payment year 2027.

Code Identity

ICD-10-CM Code
A42.7
Billable Status
Yes — Valid for Submission
Code Describes
Actinomycotic sepsis
Short Description
Actinomycotic sepsis
Same as the full description in the CMS dataset.
Parent Code
Actinomycosis

Code Classification

ChapterA00–B99Certain infectious and parasitic diseases
SectionA30-A49Other bacterial diseases
CategoryA42Actinomycosis
This CodeA42.7Actinomycotic sepsis

Medicare Risk Adjustment (HCC)Billing

A42.7 maps to a payment category in the CMS-HCC model used to risk-adjust Medicare Advantage payments. Weights are the published community factors for payment year 2027.

CMS-HCC V28 Category (Payment Model)
HCC 2— Septicemia, Sepsis, Systemic Inflammatory Response Syndrome/Shock
Payment HCC · PY 2027 one of 52 ICD-10-CM codes in this category
Risk Adjustment Factor (RAF) Weight
+0.500
community, non-dual, aged · ranges 0.447–0.780 across segments
Hierarchy
Top of its hierarchy
HCC 2 is not superseded by any other condition category
Prior Model (CMS-HCC V24)
HCC 2
V24 retired V28 pays 100% of MA risk scores since PY 2026
Other CMS Models
PACE (CMS-HCC V22): HCC 2 · ESRD (V21): HCC 2 · ESRD (V24): HCC 2
ESRD V21 weights: 0.081 dialysis, 0.274–0.428 functioning graft · ESRD V24 weights: 0.087 dialysis, 0.270–0.532 functioning graft
Part D (RxHCC)
Not mapped
A42.7 does not risk-adjust in the RxHCC prescription drug model

Source: CMS Payment Year 2027 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Sepsis caused by Actinomyces
  • Sepsis caused by anaerobic bacteria

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to A42.7: its own notes plus those printed at A42 and Chapter 1. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From Chapter 1 (A00-B99) Certain infectious and parasitic diseases applies to 1,068 codes
  • diseases generally recognized as communicable or transmissible

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From A42 Actinomycosis applies to 8 codes

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Chapter 1 (A00-B99) Certain infectious and parasitic diseases applies to 1,068 codes
  • carrier or suspected carrier of infectious disease (Z22.-)
  • certain localized infections - see body system-related chapters
  • infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium (O98.-)
  • infectious and parasitic diseases specific to the perinatal period (P35-P39)
  • influenza and other acute respiratory infections (J00-J22)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

From Chapter 1 (A00-B99) Certain infectious and parasitic diseases applies to 1,068 codes
  • code to identify resistance to antimicrobial drugs (Z16.-)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name A42.7, its category, or a range that includes it.

Excludes2 1

These codes carry an Excludes2 note naming A42.7: its condition is not part of those codes, and both may be reported when the patient has both.

  • A41 Other sepsis
    sepsis (due to) (in) actinomycotic (A42.7)

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INF003
Bacterial infections
Default principal diagnosis: inpatient No · outpatient No
CCSR INF002
Septicemia
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Actinomycosis

    infections with bacteria of the genus actinomyces.

Patient EducationClinical

Bacterial Infections

Bacteria are tiny organisms (living things) that have only one cell. Under a microscope, they look like balls, rods, or spirals. They can be found almost everywhere on Earth. There are lots of bacteria in and on your body. In fact, your body has about 10 times more bacteria cells than human cells.

The full article covers:

  • What are bacteria?
  • How do bacterial infections spread?
  • What are the treatments for bacterial infections?
  • Can bacterial infections be prevented?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert A42.7 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
038.8 Septicemia NEC
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.
ICD-9-CM
995.91 Sepsis
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About A42.7Overview

What is the ICD-10 code for actinomycotic sepsis?

The ICD-10-CM code for actinomycotic sepsis is A42.7 (sometimes written as A427). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is A42.7 (Actinomycosis) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report actinomycotic sepsis on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does A42.7 group to?

When actinomycotic sepsis is the principal diagnosis on an inpatient stay, it groups to MS-DRG 793, 791, 974, 976, 872, 975, 871, 870, with relative weights from 0.7879 to 6.9432 depending on complications. Higher weights mean higher Medicare reimbursement.

Is A42.7 a CC or MCC?

CMS lists A42.7 as an MCC (major complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it places the inpatient stay in the highest-weighted DRG of its severity family. It does not count when the principal diagnosis is one of the 46 closely related codes in its exclusion list.

Can A42.7 be reported with B47.1?

Not as a rule. The Excludes1 note at A42, which applies to A42.7, lists "actinomycetoma (B47.1)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

What HCC is A42.7?

A42.7 (actinomycotic sepsis) maps to CMS-HCC Category 2 (Septicemia, Sepsis, Systemic Inflammatory Response Syndrome/Shock), commonly written as HCC 2, in the CMS-HCC V28 model used for Medicare Advantage risk adjustment in payment year 2027. It mapped to HCC 2 under the retired V24 model. It also maps in the PACE (CMS-HCC V22), ESRD (V21), and ESRD (V24) models. It does not map to any RxHCC in the Part D prescription drug model.

Does A42.7 risk-adjust for Medicare Advantage payment?

Yes. When documented and reported on a Medicare Advantage encounter, A42.7 adds a risk adjustment factor of about 0.500 to the beneficiary's RAF score for a community, non-dual, aged enrollee (published V28 weights range from 0.447 to 0.780 depending on the payment segment). HCC 2 sits at the top of its hierarchy, so no other condition category supersedes it. See the full factor table on the HCC 2 category page.