Other sepsis (A41) ICD-10-CM
The A41 code range covers other sepsis with 19 ICD-10-CM diagnosis codes. 15 of them are billable and valid for claim submission in fiscal year 2027, and the category headers group them but cannot themselves be billed.
Code First
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions, the ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists, there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation.
- , if applicable, postprocedural sepsis T81.44
- sepsis due to central venous catheter T80.211
- sepsis during labor O75.3
- sepsis following abortion, ectopic or molar pregnancy O03.37 O03.87 O04.87 O07.37 O08.82
- sepsis following immunization T88.0
- sepsis following infusion, transfusion or therapeutic injection T80.22 T80.29
Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
Type 2 Excludes
A type 2 excludes note represents "Not included here". An excludes2 note indicates that the condition excluded is not part of the condition represented by the code, but a patient may have both conditions at the same time. When an Excludes2 note appears under a code, it is acceptable to use both the code and the excluded code together, when appropriate.
- sepsis due to in actinomycotic A42.7
- sepsis due to in anthrax A22.7
- sepsis due to in candidal B37.7
- sepsis due to in Erysipelothrix A26.7
- sepsis due to in extraintestinal yersiniosis A28.2
- sepsis due to in gonococcal A54.86
- sepsis due to in herpesviral B00.7
- sepsis due to in listerial A32.7
- sepsis due to in melioidosis A24.1
- sepsis due to in meningococcal A39.2 A39.4
- sepsis due to in plague A20.7
- sepsis due to in tularemia A21.7
- toxic shock syndrome A48.3
Codes in the A41 Range 19 codes · 15 billable
- A41 Other sepsisNon-billable
- A41.0 Sepsis due to Staphylococcus aureusNon-billable
- A41.01 Sepsis due to Methicillin susceptible Staphylococcus aureus
- A41.02 Sepsis due to Methicillin resistant Staphylococcus aureus
- A41.1 Sepsis due to other specified staphylococcus
- A41.2 Sepsis due to unspecified staphylococcus
- A41.3 Sepsis due to Hemophilus influenzae
- A41.4 Sepsis due to anaerobes
- A41.5 Sepsis due to other Gram-negative organismsNon-billable
- A41.50 Gram-negative sepsis, unspecified
- A41.51 Sepsis due to Escherichia coli [E. coli]
- A41.52 Sepsis due to Pseudomonas
- A41.53 Sepsis due to Serratia
- A41.54 Sepsis due to Acinetobacter baumannii
- A41.59 Other Gram-negative sepsis
- A41.8 Other specified sepsisNon-billable
- A41.81 Sepsis due to Enterococcus
- A41.89 Other specified sepsis
- A41.9 Sepsis, unspecified organism
Clinical Terms in This Code Range
Definitions from the National Library of Medicine for conditions coded in the A41 range.
Sepsis
Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.
About the A41 Code Range
Sepsis appears here under other bacterial diseases. The subdivisions distinguish named organisms, other specified sepsis, and sepsis with an unspecified organism.
The Staphylococcus aureus branch, A41.0, separates methicillin-susceptible from methicillin-resistant sepsis. Other staphylococcus codes distinguish a specified organism from an unspecified one. Separate subdivisions name Hemophilus influenzae and anaerobes.
The Gram-negative branch, A41.5, distinguishes named organisms such as E. coli from unspecified or other Gram-negative sepsis. A41.8 includes Enterococcus and other specified sepsis; A41.9 identifies sepsis with an unspecified organism.
Questions About This Page
How many billable codes are in the A41 range?
Of the 19 codes in this range, 15 are billable and valid for claim submission from October 1, 2026 through September 30, 2027. Category header codes group them but cannot be reported on claims.
What does the A41 range classify?
The range classifies other sepsis. Each code links to its own reference page with billing status, MS-DRG grouping, coding notes, and clinical information.
Related References
Source: CMS FY 2027 ICD-10-CM Tabular List and order file, effective October 1, 2026 through September 30, 2027.
