Version 2024

2024 ICD-10-CM Diagnosis Code A41

Other sepsis

ICD-10-CM Code:
ICD-10 Code for:
Other sepsis
Is Billable?
Not Valid for Submission
Code Navigator:

Code Classification

  • Certain infectious and parasitic diseases
    • Other bacterial diseases
      • Other sepsis

A41 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of other sepsis. The code is not specific and is NOT valid for the year 2024 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Specific Coding Applicable to Other sepsis

Non-specific codes like A41 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for other sepsis:

  • A41.0 for Sepsis due to Staphylococcus aureus - NON-BILLABLE CODE

  • Use A41.01 for Sepsis due to Methicillin susceptible Staphylococcus aureus - BILLABLE CODE

  • Use A41.02 for Sepsis due to Methicillin resistant Staphylococcus aureus - BILLABLE CODE

  • Use A41.1 for Sepsis due to other specified staphylococcus - BILLABLE CODE

  • Use A41.2 for Sepsis due to unspecified staphylococcus - BILLABLE CODE

  • Use A41.3 for Sepsis due to Hemophilus influenzae - BILLABLE CODE

  • Use A41.4 for Sepsis due to anaerobes - BILLABLE CODE

  • A41.5 for Sepsis due to other Gram-negative organisms - NON-BILLABLE CODE

  • Use A41.50 for Gram-negative sepsis, unspecified - BILLABLE CODE

  • Use A41.51 for Sepsis due to Escherichia coli [E. coli] - BILLABLE CODE

  • Use A41.52 for Sepsis due to Pseudomonas - BILLABLE CODE

  • Use A41.53 for Sepsis due to Serratia - BILLABLE CODE

  • Use A41.54 for Sepsis due to Acinetobacter baumannii - BILLABLE CODE

  • Use A41.59 for Other Gram-negative sepsis - BILLABLE CODE

  • A41.8 for Other specified sepsis - NON-BILLABLE CODE

  • Use A41.81 for Sepsis due to Enterococcus - BILLABLE CODE

  • Use A41.89 for Other specified sepsis - BILLABLE CODE

  • Use A41.9 for Sepsis, unspecified organism - BILLABLE CODE

Clinical Information

  • Burkholderia Infections

    infections with bacteria of the genus burkholderia.
  • Lemierre Syndrome

    a superinfection of the damaged oropharyngeal mucosa by fusobacterium necrophorum leading to the secondary septic thrombophlebitis of the internal jugular vein.
  • Neonatal Sepsis

    blood infection that occurs in an infant younger than 90 days old. early-onset sepsis is seen in the first week of life and most often appears within 24 hours of birth. late-onset occurs after 1 week and before 3 months of age.
  • Pregnancy Complications, Infectious

    the co-occurrence of pregnancy and an infection. the infection may precede or follow fertilization.
  • Puerperal Infection

    an infection occurring in puerperium, the period of 6-8 weeks after giving birth.
  • Sepsis

    systemic inflammatory response syndrome with a proven or suspected infectious etiology. when sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. when sepsis is accompanied by hypotension despite adequate fluid infusion, it is called septic shock.
  • Sepsis-Associated Encephalopathy

    acute neurological dysfunction during severe sepsis in the absence of direct brain infection characterized by systemic inflammation and blood brain barrier perturbation.
  • Systemic Inflammatory Response Syndrome

    a systemic inflammatory response to a variety of clinical insults, characterized by two or more of the following conditions: (1) fever >38 degrees c or hypothermia <36 degrees c; (2) tachycardia >90 beat/minute; (3) tachypnea >24 breaths/minute; (4) leukocytosis >12,000 cells/cubic mm or 10% immature forms. while usually related to infection, sirs can also be associated with noninfectious insults such as trauma; burns; or pancreatitis. if infection is involved, a patient with sirs is said to have sepsis.
  • Burkholderia

    a genus of gram-negative, aerobic, rod-shaped bacteria originally classified as members of the pseudomonadaceae.

Tabular List of Diseases and Injuries

The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.

Code First

Code First
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions, the ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists, there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation.

Type 1 Excludes

Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • bacteremia NOS R78.81
  • neonatal P36
  • puerperal sepsis O85
  • streptococcal sepsis A40

Type 2 Excludes

Type 2 Excludes
A type 2 excludes note represents "Not included here". An excludes2 note indicates that the condition excluded is not part of the condition represented by the code, but a patient may have both conditions at the same time. When an Excludes2 note appears under a code, it is acceptable to use both the code and the excluded code together, when appropriate.
  • sepsis due to in actinomycotic A42.7
  • sepsis due to in anthrax A22.7
  • sepsis due to in candidal B37.7
  • sepsis due to in Erysipelothrix A26.7
  • sepsis due to in extraintestinal yersiniosis A28.2
  • sepsis due to in gonococcal A54.86
  • sepsis due to in herpesviral B00.7
  • sepsis due to in listerial A32.7
  • sepsis due to in melioidosis A24.1
  • sepsis due to in meningococcal A39.2 A39.4
  • sepsis due to in plague A20.7
  • sepsis due to in tularemia A21.7
  • toxic shock syndrome A48.3

Patient Education


What is sepsis?

Sepsis is your body's overactive and extreme response to an infection. Sepsis is a life-threatening medical emergency. Without quick treatment, it can lead to tissue damage, organ failure, and even death.

What causes sepsis?

Sepsis happens when an infection you already have triggers a chain reaction throughout your body. Bacterial infections are the most common cause, but other types of infections can also cause it.

The infections are often in the lungs, stomach, kidneys, or bladder. It's possible for sepsis to begin with a small cut that gets infected or with an infection that develops after surgery. Sometimes, sepsis can occur in people who didn't even know that they had an infection.

Who is at risk for sepsis?

Anyone with an infection could get sepsis. But certain people are at higher risk:

  • Adults 65 or older
  • People with chronic conditions, such as diabetes, lung disease, cancer, and kidney disease
  • People with weakened immune systems
  • Pregnant women
  • Children younger than one

What are the symptoms of sepsis?

Sepsis can cause one or more of these symptoms:

  • Rapid breathing and heart rate
  • Shortness of breath
  • Confusion or disorientation
  • Extreme pain or discomfort
  • Fever, shivering, or feeling very cold
  • Clammy or sweaty skin

It's important to get medical care right away if you think you might have sepsis or if your infection is not getting better or is getting worse.

What other problems can sepsis cause?

Severe cases of sepsis can lead to septic shock, where your blood pressure drops to a dangerous level and multiple organs can fail.

How is sepsis diagnosed?

Your health care provider may use many tools to make a diagnosis:

  • A medical history, which includes asking about your symptoms
  • A physical exam, including checking vital signs (your temperature, blood pressure, heart rate, and breathing)
  • Lab tests that check for signs of infection or organ damage
  • Imaging tests such as an x-ray or a CT scan to find the location of the infection

Many of the signs and symptoms of sepsis can also be caused by other medical conditions. This may make sepsis hard to diagnose in its early stages.

What are the treatments for sepsis?

It is very important to get treatment right away. Treatment usually includes:

  • Antibiotics
  • Maintaining blood flow to organs. This may involve getting oxygen and intravenous (IV) fluids.
  • Treating the source of the infection
  • If needed, medicines to increase blood pressure

In serious cases, you might need kidney dialysis or a breathing tube. Some people need surgery to remove tissue damaged by the infection.

Can sepsis be prevented?

To prevent sepsis, you should try to prevent getting an infection:

  • Take good care of any chronic health conditions that you have
  • Get recommended vaccines
  • Practice good hygiene, such as handwashing
  • Keep cuts clean and covered until healed

NIH: National Institute of General Medical SciencesCenters for Disease Control and Prevention

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Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.