2027 ICD-10-CM Diagnosis Code A41Other sepsis

ICD-10-CM Codes›A00–B99›A30-A49›A41

ICD-10-CM A41
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

A41 is a non-billable ICD-10-CM category code for other sepsis, so it cannot be submitted on claims. Use a more specific code from this category instead, such as A41.01, A41.02, A41.1, and A41.2.

Code Identity

ICD-10-CM Code
A41
Billable Status
No — Non-Billable Category
Code Describes
Other sepsis
Short Description
Other sepsis
Same as the full description in the CMS dataset.
Chapter
A30-A49
Other bacterial diseases

Code Classification

ChapterA00–B99Certain infectious and parasitic diseases
SectionA30-A49Other bacterial diseases
CategoryA41Other sepsis
This CodeA41Other sepsis

Specific Coding for Other sepsisOverview

Non-specific codes like A41 require more characters. Use one of these billable codes instead:

  • A41.0 for Sepsis due to Staphylococcus aureus

  • Use A41.01 for Sepsis due to Methicillin susceptible Staphylococcus aureus

  • Use A41.02 for Sepsis due to Methicillin resistant Staphylococcus aureus

  • Use A41.1 for Sepsis due to other specified staphylococcus

  • Use A41.2 for Sepsis due to unspecified staphylococcus

  • Use A41.3 for Sepsis due to Hemophilus influenzae

  • Use A41.4 for Sepsis due to anaerobes

  • A41.5 for Sepsis due to other Gram-negative organisms

  • Use A41.50 for Gram-negative sepsis, unspecified

  • Use A41.51 for Sepsis due to Escherichia coli [E. coli]

  • Use A41.52 for Sepsis due to Pseudomonas

  • Use A41.53 for Sepsis due to Serratia

  • Use A41.54 for Sepsis due to Acinetobacter baumannii

  • Use A41.59 for Other Gram-negative sepsis

  • A41.8 for Other specified sepsis

  • Use A41.81 for Sepsis due to Enterococcus

  • Use A41.89 for Other specified sepsis

  • Use A41.9 for Sepsis, unspecified organism

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to A41: its own notes plus those printed at Chapter 1. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From Chapter 1 (A00-B99) Certain infectious and parasitic diseases applies to 1,068 codes
  • diseases generally recognized as communicable or transmissible

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

On A41 itself
  • sepsis (due to) (in) actinomycotic (A42.7)
  • sepsis (due to) (in) anthrax (A22.7)
  • sepsis (due to) (in) candidal (B37.7)
  • sepsis (due to) (in) Erysipelothrix (A26.7)
  • sepsis (due to) (in) extraintestinal yersiniosis (A28.2)
  • sepsis (due to) (in) gonococcal (A54.86)
  • sepsis (due to) (in) herpesviral (B00.7)
  • sepsis (due to) (in) listerial (A32.7)
  • sepsis (due to) (in) melioidosis (A24.1)
  • sepsis (due to) (in) meningococcal (A39.2-A39.4)
  • sepsis (due to) (in) plague (A20.7)
  • sepsis (due to) (in) tularemia (A21.7)
  • toxic shock syndrome (A48.3)
From Chapter 1 (A00-B99) Certain infectious and parasitic diseases applies to 1,068 codes
  • carrier or suspected carrier of infectious disease (Z22.-)
  • certain localized infections - see body system-related chapters
  • infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium (O98.-)
  • infectious and parasitic diseases specific to the perinatal period (P35-P39)
  • influenza and other acute respiratory infections (J00-J22)

Code First

The underlying condition named in the note is sequenced before this code.

Use Additional Code

Add a second code, after this one, to fully describe the condition.

From Chapter 1 (A00-B99) Certain infectious and parasitic diseases applies to 1,068 codes
  • code to identify resistance to antimicrobial drugs (Z16.-)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name A41, its category, or a range that includes it.

Code First 3

These codes say to code first a condition named in the note, and A41 is one of the conditions named.

  • I5A Non-ischemic myocardial injury (non-traumatic)
    sepsis (A41.-)
  • N08 Glomerular disorders in diseases classified elsewhere
    sepsis (A40.0-A41.9) names A40.0-A41.9, which includes this code
  • N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
    sepsis (A40.0-A41.9) names A40.0-A41.9, which includes this code

Use Additional Code 6

These codes say to use an additional code from the note, and A41 is one of the codes named.

  • J95.02 Infection of tracheostomy stoma
    sepsis (A40, A41.-)
  • K94.02 Colostomy infection
    sepsis (A40.-, A41.-)
  • K94.12 Enterostomy infection
    sepsis (A40.-, A41.-)
  • K94.22 Gastrostomy infection
    sepsis (A40.-, A41.-)
  • K95.01 Infection due to gastric band procedure
    sepsis (A40.-, A41.-)
  • K95.81 Infection due to other bariatric procedure
    sepsis (A40.-, A41.-)

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Patient EducationClinical

Sepsis

Sepsis is your body's overactive and extreme response to an infection. Sepsis is a life-threatening medical emergency. Without quick treatment, it can lead to tissue damage, organ failure, and even death.

The full article covers:

  • What is sepsis?
  • What causes sepsis?
  • Who is more likely to develop sepsis?
  • What are the symptoms of sepsis?
  • What other problems can sepsis cause?
  • How is sepsis diagnosed?
  • What are the treatments for sepsis?
  • Can sepsis be prevented?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About A41Overview

What is the ICD-10 code for other sepsis?

A41 is the ICD-10-CM category for other sepsis, but it is a non-billable header: claims need a more specific code from this category, listed on this page.

Is A41 (Other sepsis) a billable code?

No. This is a category header that groups the codes for other sepsis, and headers cannot be submitted on claims. Claims for other sepsis need a more specific code from this category, such as A41.01, A41.02, and A41.1.

Can A41 be reported with R78.81?

Not as a rule. The Excludes1 note on A41 lists "bacteremia NOS (R78.81)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

What is coded first with A41?

The Code First note reads: if applicable, postprocedural sepsis (T81.44-); sepsis due to central venous catheter (T80.211-); sepsis during labor (O75.3); sepsis following abortion, ectopic or molar pregnancy (O03.37, O03.87, O04.87, O07.37, O08.82); sepsis following immunization (T88.0-); and 1 more listed in the Instructional Notes section. When one of these applies, it is sequenced before A41.