2026 ICD-10-CM Diagnosis Code A41Other sepsis

ICD-10-CM Codes›A00–B99›A30-A49›A41

ICD-10-CM A41
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

A41 is a non-billable ICD-10-CM category code for other sepsis, so it cannot be submitted on claims. Use a more specific code from this category instead, such as A41.01, A41.02, A41.1, and A41.2.

Code Identity

ICD-10-CM Code
A41
Billable Status
No — Non-Billable Category
Code Describes
Other sepsis
Chapter
A30-A49
Other bacterial diseases

Code Classification

ChapterA00–B99Certain infectious and parasitic diseases
SectionA30-A49Other bacterial diseases
CategoryA41Other sepsis
This CodeA41Other sepsis

Specific Coding for Other sepsisOverview

Non-specific codes like A41 require more characters. Use one of these billable codes instead:

  • A41.0 for Sepsis due to Staphylococcus aureus

  • Use A41.01 for Sepsis due to Methicillin susceptible Staphylococcus aureus

  • Use A41.02 for Sepsis due to Methicillin resistant Staphylococcus aureus

  • Use A41.1 for Sepsis due to other specified staphylococcus

  • Use A41.2 for Sepsis due to unspecified staphylococcus

  • Use A41.3 for Sepsis due to Hemophilus influenzae

  • Use A41.4 for Sepsis due to anaerobes

  • A41.5 for Sepsis due to other Gram-negative organisms

  • Use A41.50 for Gram-negative sepsis, unspecified

  • Use A41.51 for Sepsis due to Escherichia coli [E. coli]

  • Use A41.52 for Sepsis due to Pseudomonas

  • Use A41.53 for Sepsis due to Serratia

  • Use A41.54 for Sepsis due to Acinetobacter baumannii

  • Use A41.59 for Other Gram-negative sepsis

  • A41.8 for Other specified sepsis

  • Use A41.81 for Sepsis due to Enterococcus

  • Use A41.89 for Other specified sepsis

  • Use A41.9 for Sepsis, unspecified organism

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Code First

Type 1 Excludes

  • bacteremia NOS R78.81
  • neonatal P36
  • puerperal sepsis O85
  • streptococcal sepsis A40

Type 2 Excludes

  • sepsis due to in actinomycotic A42.7
  • sepsis due to in anthrax A22.7
  • sepsis due to in candidal B37.7
  • sepsis due to in Erysipelothrix A26.7
  • sepsis due to in extraintestinal yersiniosis A28.2
  • sepsis due to in gonococcal A54.86
  • sepsis due to in herpesviral B00.7
  • sepsis due to in listerial A32.7
  • sepsis due to in melioidosis A24.1
  • sepsis due to in meningococcal A39.2 A39.4
  • sepsis due to in plague A20.7
  • sepsis due to in tularemia A21.7
  • toxic shock syndrome A48.3

Clinical InformationClinical

  • Burkholderia Infections

    infections with bacteria of the genus burkholderia.

  • Lemierre Syndrome

    a superinfection of the damaged oropharyngeal mucosa by fusobacterium necrophorum leading to the secondary septic thrombophlebitis of the internal jugular vein.

  • Neonatal Sepsis

    blood infection that occurs in an infant younger than 90 days old. early-onset sepsis is seen in the first week of life and most often appears within 24 hours of birth. late-onset occurs after 1 week and before 3 months of age.

  • Pregnancy Complications, Infectious

    the co-occurrence of pregnancy and an infection. the infection may precede or follow fertilization.

  • Puerperal Infection

    an infection occurring in puerperium, the period of 6-8 weeks after giving birth.

  • Sepsis

    systemic inflammatory response syndrome with a proven or suspected infectious etiology. when sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. when sepsis is accompanied by hypotension despite adequate fluid infusion, it is called septic shock.

  • Sepsis-Associated Encephalopathy

    acute neurological dysfunction during severe sepsis in the absence of direct brain infection characterized by systemic inflammation and blood brain barrier perturbation.

  • Systemic Inflammatory Response Syndrome

    a systemic inflammatory response to a variety of clinical insults, characterized by two or more of the following conditions: (1) fever >38 degrees c or hypothermia <36 degrees c; (2) tachycardia >90 beat/minute; (3) tachypnea >24 breaths/minute; (4) leukocytosis >12,000 cells/cubic mm or 10% immature forms. while usually related to infection, sirs can also be associated with noninfectious insults such as trauma; burns; or pancreatitis. if infection is involved, a patient with sirs is said to have sepsis.

  • Burkholderia

    a genus of gram-negative, aerobic, rod-shaped bacteria originally classified as members of the pseudomonadaceae.

Patient EducationClinical

Sepsis

Sepsis is your body's overactive and extreme response to an infection. Sepsis is a life-threatening medical emergency. Without quick treatment, it can lead to tissue damage, organ failure, and even death.

The full article covers:

  • What is sepsis?
  • What causes sepsis?
  • Who is more likely to develop sepsis?
  • What are the symptoms of sepsis?
  • What other problems can sepsis cause?
  • How is sepsis diagnosed?
  • What are the treatments for sepsis?
  • Can sepsis be prevented?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About A41Overview

Is A41 (Other sepsis) a billable code?

No. This is a category header that groups the codes for other sepsis, and headers cannot be submitted on claims. Claims for other sepsis need a more specific code from this category, such as A41.01, A41.02, and A41.1.