2025 ICD-10-CM Diagnosis Code D55.9
Anemia due to enzyme disorder, unspecified
- ICD-10-CM Code:
- D55.9
- ICD-10 Code for:
- Anemia due to enzyme disorder, unspecified
- Is Billable?
- Yes - Valid for Submission
- Chronic Condition Indicator: [1]
- Chronic
- Code Navigator:
D55.9 is a billable diagnosis code used to specify a medical diagnosis of anemia due to enzyme disorder, unspecified. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2024 through September 30, 2025.
Unspecified diagnosis codes like D55.9 are acceptable when clinical information is unknown or not available about a particular condition. Although a more specific code is preferable, unspecified codes should be used when such codes most accurately reflect what is known about a patient's condition. Specific diagnosis codes should not be used if not supported by the patient's medical record.
Approximate Synonyms
The following list of clinical terms are approximate synonyms, alternative descriptions, or common phrases that might be used by patients, healthcare providers, or medical coders to describe the same condition. These synonyms and related diagnosis terms are often used when searching for an ICD-10 code, especially when the exact medical terminology is unclear. Whether you're looking for lay terms, similar diagnosis names, or common language alternatives, this list can help guide you to the correct ICD-10 classification.
- Anemia due to enzyme deficiency
- Anemia due to enzymopathy
- Chronic non-spherocytic hemolytic anemia
Clinical Classification
Clinical Classifications group individual ICD-10-CM diagnosis codes into broader, clinically meaningful categories. These categories help simplify complex data by organizing related conditions under common clinical themes.
They are especially useful for data analysis, reporting, and clinical decision-making. Even when diagnosis codes differ, similar conditions can be grouped together based on their clinical relevance. Each category is assigned a unique CCSR code that represents a specific clinical concept, often tied to a body system or medical specialty.
Hemolytic anemia
CCSR Code: BLD002
Inpatient Default: Y - Yes, default inpatient assignment for principal diagnosis or first-listed diagnosis.
Outpatient Default: Y - Yes, default outpatient assignment for principal diagnosis or first-listed diagnosis.
Clinical Information
Anemia due to Enzyme Disorder
any form of anemia that results from the absence of, or the defective action of, any enzyme.
Index to Diseases and Injuries References
The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).
- - Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) - D64.9
- - deficiency - D53.9
- - enzyme - D55.9
- - due to (in) (with)
- - enzyme disorder - D55.9
- - hemolytic - D58.9
- - due to
- - enzyme disorder - D55.9
- - hereditary - D58.9
- - due to enzyme disorder - D55.9
- - due to
- - deficiency - D53.9
Convert D55.9 to ICD-9-CM
Below are the ICD-9 codes that most closely match this ICD-10 code, based on the General Equivalence Mappings (GEMs). This ICD-10 to ICD-9 crosswalk tool is helpful for coders who need to reference legacy diagnosis codes for audits, historical claims, or approximate code comparisons.
Enzyme defic anemia NEC
ICD-9-CM: 282.3
Approximate Flag - The approximate mapping means this ICD-10 code does not have an exact ICD-9 equivalent. The matched code is the closest available option, but it may not fully capture the original diagnosis or clinical intent.
Patient Education
Anemia
If you have anemia, your blood does not carry enough oxygen to the rest of your body. The most common cause of anemia is not having enough iron. Your body needs iron to make hemoglobin. Hemoglobin is an iron-rich protein that gives the red color to blood. It carries oxygen from the lungs to the rest of the body.
Anemia has three main causes: blood loss, lack of red blood cell production, and high rates of red blood cell destruction.
Conditions that may lead to anemia include:
- Heavy periods
- Pregnancy
- Ulcers
- Colon polyps or colon cancer
- Inherited disorders
- A diet that does not have enough iron, folic acid or vitamin B12
- Blood disorders such as sickle cell anemia and thalassemia, or cancer
- Aplastic anemia, a condition that can be inherited or acquired
- G6PD deficiency, a metabolic disorder
Anemia can make you feel tired, cold, dizzy, and irritable. You may be short of breath or have a headache.
Your doctor will diagnose anemia with a physical exam and blood tests. Treatment depends on the kind of anemia you have.
NIH: National Heart, Lung, and Blood Institute
[Learn More in MedlinePlus]
Code History
- FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
- FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
- FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
- FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
- FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
- FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
- FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
- FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
- FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.
Footnotes
[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:
- The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
- The condition places limitations on self-care, independent living, and social interactions.