D56.4 is a billable ICD-10 code used to specify a medical diagnosis of hereditary persistence of fetal hemoglobin [hpfh]. The code is valid during the fiscal year 2023 from October 01, 2022 through September 30, 2023 for the submission of HIPAA-covered transactions.
The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:
- A>gamma< beta^+^ HPFH AND beta^0^ thalassemia in cis
- Beta plus thalassemia
- Beta plus thalassemia
- Beta zero thalassemia
- Delta beta thalassemia
- Delta beta zero thalassemia
- Hereditary persistence of fetal hemoglobin
- Hereditary persistence of fetal hemoglobin delta beta plus thalassemia
- Hereditary persistence of fetal hemoglobin G gamma beta plus thalassemia
- Hereditary persistence of fetal hemoglobin thalassemia
- Hereditary persistence of fetal hemoglobin with sickle cell disease syndrome
- HPFH A gamma beta^+^ thalassemia
- HPFH deletion type
- HPFH linked to beta-globulin gene cluster
- HPFH nondeletion type
- HPFH unlinked to beta-globulin gene cluster
- Hereditary Persistence of Fetal Hemoglobin-. the persistence of substantial fetal hemoglobin production into adulthood, usually associated with hemoglobinopathies due to mutations in the alpha and/or beta chain of hemoglobin.
Index to Diseases and Injuries References
The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code(s). The following references for this diagnosis code are found in the injuries and diseases index:
Convert to ICD-9 Code
|Source ICD-10 Code||Target ICD-9 Code|
|D56.4||282.7 - Hemoglobinopathies NEC|
|Approximate Flag - The approximate mapping means there is not an exact match between the ICD-10 and ICD-9 codes and the mapped code is not a precise representation of the original code.|
Thalassemias are inherited blood disorders. If you have one, your body makes fewer healthy red blood cells and less hemoglobin. Hemoglobin is a protein that carries oxygen to the body. That leads to anemia. Thalassemias occur most often among people of Italian, Greek, Middle Eastern, Southern Asian, and African descent.
Thalassemias can be mild or severe. Some people have no symptoms or mild anemia. The most common severe type in the United States is called Cooley's anemia. It usually appears during the first two years of life. People with it may have severe anemia, slowed growth and delayed puberty, and problems with the spleen, liver, heart, or bones.
Doctors diagnose thalassemias using blood tests. Treatments include blood transfusions and treatment to remove excess iron from the body. If you have mild symptoms or no symptoms, you may not need treatment. In some severe cases, you may need a bone marrow transplant.
NIH: National Heart, Lung, and Blood Institute
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- FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
- FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
- FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
- FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
- FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
- FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
- FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
- FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016 (First year ICD-10-CM implemented into the HIPAA code set)