2027 ICD-10-CM Diagnosis Code Z90.81Acquired absence of spleen
Z90.81 is a billable ICD-10-CM diagnosis code for acquired absence of spleen. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 951. The code is not accepted as a principal diagnosis by the Medicare Code Editor and exempt from POA reporting. Coders also document this condition as asplenia. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Acquired absence of limb or organ.
Code Identity
Code Classification
Code EditsBilling
Medicare Code Editor checks that affect claim validity for Z90.81.
Present on Admission (POA)Billing
Z90.81 is exempt from POA reporting on inpatient claims to general acute care hospitals. Review the other POA exempt codes in Persons with potential health hazards related to family and personal history and certain conditions influencing health status (Z77-Z99).
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Asplenia
- Asplenia following surgical procedure
- H/O splenectomy
- Overwhelming infection in asplenic patient
- Post-splenectomy disorder
- Post-splenectomy sepsis
- Pulmonary hypertension due to hematological disorder
- Pulmonary hypertension due to post-splenectomy hematological disorder
- Sepsis in asplenic subject
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to Z90.81: its own notes plus those printed at Z90, block Z77-Z99, and Chapter 21. A note printed at a category, block or chapter applies to every code under it.
Includes
Further defines, or gives examples of, the content of the category.
- postprocedural or post-traumatic loss of body part NEC
Excludes1
Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.
- congenital absence - see Alphabetical Index
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
Code Also
A second code may be needed to fully describe the condition; the note gives no sequencing direction.
Notes
General instructions on how these codes are used.
- Z codes represent reasons for encounters. A corresponding procedure code must accompany a Z code if a procedure is performed. Categories Z00-Z99 are provided for occasions when circumstances other than a disease, injury or external cause classifiable to categories A00-Y89 are recorded as 'diagnoses' or 'problems'. This can arise in two main ways:
- (a) When a person who may or may not be sick encounters the health services for some specific purpose, such as to receive limited care or service for a current condition, to donate an organ or tissue, to receive prophylactic vaccination (immunization), or to discuss a problem which is in itself not a disease or injury.
- (b) When some circumstance or problem is present which influences the person's health status but is not in itself a current illness or injury.
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Referenced in Other NotesGuidance
Instructional notes printed at other codes that name Z90.81, its category, or a range that includes it.
Excludes1 1
These codes carry an Excludes1 note naming Z90.81: they are not reported together with it, unless the two conditions are unrelated.
- D73.0 Hyposplenismpostsurgical absence of spleen (Z90.81)
Excludes2 1
These codes carry an Excludes2 note naming Z90.81: its condition is not part of those codes, and both may be reported when the patient has both.
- M95 Other acquired deformities of musculoskeletal system and connective tissue
Use Additional Code 1
These codes say to use an additional code from the note, and Z90.81 is one of the codes named.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Status (post) See Also: Presence (of);
splenectomy Z90.81
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Patient EducationClinical
Spleen Diseases
Your spleen is an organ above your stomach and under your ribs on your left side. It is about as big as your fist. The spleen is part of your lymphatic system, which fights infection and keeps your body fluids in balance. It contains white blood cells that fight germs.
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert Z90.81 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About Z90.81Overview
What is the ICD-10 code for acquired absence of spleen?
The ICD-10-CM code for acquired absence of spleen is Z90.81 (sometimes written as Z9081). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is Z90.81 (Acquired absence of other organs) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report acquired absence of spleen on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does Z90.81 group to?
On inpatient claims, acquired absence of spleen maps to MS-DRG 951 (other Factors Influencing Health Status), which carries a relative weight of 0.5574. Higher weights mean higher Medicare reimbursement.
Can Z90.81 be a principal diagnosis?
No. The Medicare Code Editor rejects this code as a principal diagnosis because acquired absence of spleen describes a circumstance that influences health status rather than a current illness. Report it as a secondary diagnosis.
Is Z90.81 exempt from POA reporting?
Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for acquired absence of spleen on inpatient claims. The code appears in the Persons with potential health hazards related to family and personal history and certain conditions influencing health status (Z77-Z99) range of the CMS exempt list.
