2027 ICD-10-CM Diagnosis Code Z72.53High risk bisexual behavior

ICD-10-CM Codes›Z00–Z99›Z69-Z76›Z72

ICD-10-CM Z72.53
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

Z72.53 is a billable ICD-10-CM diagnosis code for high risk bisexual behavior. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 951. The code is not accepted as a principal diagnosis by the Medicare Code Editor and exempt from POA reporting. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Lifestyle/life management factors.

Code Identity

ICD-10-CM Code
Z72.53
Billable Status
Yes — Valid for Submission
Code Describes
High risk bisexual behavior
Short Description
High risk bisexual behavior
Same as the full description in the CMS dataset.
Parent Code
Z72.5
High risk sexual behavior

Code Classification

ChapterZ00–Z99Factors influencing health status and contact with health services
SectionZ69-Z76Persons encountering health services in other circumstances
CategoryZ72Problems related to lifestyle
This CodeZ72.53High risk bisexual behavior

Code EditsBilling

Medicare Code Editor checks that affect claim validity for Z72.53.

Unacceptable principal diagnosis
There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Present on Admission (POA)Billing

Z72.53 is exempt from POA reporting on inpatient claims to general acute care hospitals. Review the other POA exempt codes in Persons encountering health services in other circumstances (Z69-Z76).

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • High risk bisexual behavior
  • High risk sexual behavior

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to Z72.53: its own notes plus those printed at Z72.5, Z72, and Chapter 21. A note printed at a category, block or chapter applies to every code under it.

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From Z72.5 High risk sexual behavior applies to 3 codes
  • paraphilias (F65)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Z72 Problems related to lifestyle applies to 14 codes
  • problems related to life-management difficulty (Z73.-)
  • problems related to socioeconomic and psychosocial circumstances (Z55-Z65)

Notes

General instructions on how these codes are used.

From Chapter 21 (Z00-Z99) Factors influencing health status and contact with health services applies to 1,425 codes
  • Z codes represent reasons for encounters. A corresponding procedure code must accompany a Z code if a procedure is performed. Categories Z00-Z99 are provided for occasions when circumstances other than a disease, injury or external cause classifiable to categories A00-Y89 are recorded as 'diagnoses' or 'problems'. This can arise in two main ways:
  • (a) When a person who may or may not be sick encounters the health services for some specific purpose, such as to receive limited care or service for a current condition, to donate an organ or tissue, to receive prophylactic vaccination (immunization), or to discuss a problem which is in itself not a disease or injury.
  • (b) When some circumstance or problem is present which influences the person's health status but is not in itself a current illness or injury.

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name Z72.53, its category, or a range that includes it.

Code Also 1

These codes say Z72.53 may also be needed to fully describe the condition. The note gives no sequencing direction.

  • Z29.81 Encounter for HIV pre-exposure prophylaxis
    high risk sexual behavior (Z72.5-) names Z72.5-, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR FAC020
Lifestyle/life management factors
Default principal diagnosis: inpatient No · outpatient Yes

Convert Z72.53 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
V69.2 High-risk sexual behavr
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About Z72.53Overview

What is the ICD-10 code for high risk bisexual behavior?

The ICD-10-CM code for high risk bisexual behavior is Z72.53 (sometimes written as Z7253). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is Z72.53 (High risk sexual behavior) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report high risk bisexual behavior on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does Z72.53 group to?

On inpatient claims, high risk bisexual behavior maps to MS-DRG 951 (other Factors Influencing Health Status), which carries a relative weight of 0.5574. Higher weights mean higher Medicare reimbursement.

Can Z72.53 be a principal diagnosis?

No. The Medicare Code Editor rejects this code as a principal diagnosis because high risk bisexual behavior describes a circumstance that influences health status rather than a current illness. Report it as a secondary diagnosis.

Is Z72.53 exempt from POA reporting?

Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for high risk bisexual behavior on inpatient claims. The code appears in the Persons encountering health services in other circumstances (Z69-Z76) range of the CMS exempt list.