2026 ICD-10-CM Diagnosis Code T66.XXXARadiation sickness, unspecified, initial encounter

ICD-10-CM CodesS00–T88T66-T78T66

ICD-10-CM T66.XXXA
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

T66.XXXA is a billable ICD-10-CM diagnosis code for radiation sickness, unspecified, initial encounter. The 7th character A marks it as an initial encounter code, used while the patient is receiving active treatment. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 922 through 923. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Effect of other external causes, initial encounter.

Code Identity

ICD-10-CM Code
T66.XXXA
Billable Status
Yes — Valid for Submission
Code Describes
Radiation sickness, unspecified, initial encounter
Short Description
Radiation sickness, unspecified, initial encounter
Same as the full description in the CMS dataset.
Parent Code
Radiation sickness, unspecified

Code Classification

ChapterS00–T88Injury, poisoning and certain other consequences of external causes
SectionT66-T78Other and unspecified effects of external causes
CategoryT66Radiation sickness, unspecified
This CodeT66.XXXARadiation sickness, unspecified, initial encounter

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Acquired pancytopenia
  • Acute radiation disease
  • Acute radiation nephritis
  • Acute radiation otitis externa
  • Acute radiation syndrome
  • Acute vomiting
  • Anemia caused by physical agent
  • Anemia due to radiation
  • Aplastic anemia due to radiation
  • Cancer dataset administrative items
  • Chronic radiation nephritis
  • Chronic radiation sickness
  • Disorder caused by radiation
  • Disorder due to radiotherapy
  • Disorder of bone marrow caused by ionizing radiation
  • Disorder of conjunctiva caused by radiation
  • Disorder of eyelid caused by radiation
  • Disorder of macula of retina caused by radiation
  • Disorder of optic nerve caused by radiation
  • Disorder of retina caused by radiation
  • Disorder of sclera caused by radiation
  • Effect of ionizing radiation
  • Effect of radiation
  • Effects of occupational exposure to radiation
  • Effects of overexposure to electromagnetic radiation
  • Hematopoietic subsyndrome of acute radiation syndrome
  • Infertility caused by radiation
  • Nausea and vomiting
  • Nausea and vomiting caused by radiation
  • Occupational injury
  • Radiation agranulocytosis
  • Radiation nephritis
  • Radiation sickness
  • Radiation sickness following radiation therapy
  • Radiation-induced male infertility
  • Radiotherapy course change due to acute radiotherapy toxicity
  • Reason for change in radiotherapy course
  • Subacute radiation sickness
  • Toxicity due to radiotherapy

Coding GuidelinesGuidance

The appropriate 7th character is to be added to each code from block Radiation sickness, unspecified (T66). Use the following options for the applicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INJ021
Effect of other external causes, initial encounter
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Acute Radiation Syndrome

    a condition caused by a brief whole body exposure to more than one sievert dose equivalent of radiation. acute radiation syndrome is initially characterized by anorexia; nausea; vomiting; but can progress to hematological, gastrointestinal, neurological, pulmonary, and other major organ dysfunction.
  • Aplastic Anemia due to Radiation

    aplastic anemia caused by excessive absorption of radiation by the bone marrow.

Patient EducationClinical

Radiation Exposure

Radiation is energy. It travels in the form of energy waves or high-speed particles. Radiation can occur naturally or be man-made. There are two types:

The full article covers:

  • What is radiation?
  • What are the sources of radiation exposure?
  • What are the health effects of radiation exposure?
  • What are the treatments for acute radiation sickness?
  • How can radiation exposure be prevented?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert T66.XXXA to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
990 Effects radiation NOS
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About T66.XXXAOverview

Is T66.XXXA (Radiation sickness, unspecified) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report radiation sickness, unspecified, initial encounter on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What does the 7th character A in T66.XXXA mean?

The final character A marks the initial encounter: use it while the patient is receiving active treatment for radiation sickness, unspecified, such as an emergency visit or first evaluation.

What MS-DRG does T66.XXXA group to?

When radiation sickness, unspecified, initial encounter is the principal diagnosis on an inpatient stay, it groups to MS-DRG 922, 923, with relative weights from 1.0177 to 1.7494 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of T66.XXXA?

Under the General Equivalence Mappings, radiation sickness, unspecified, initial encounter converts to ICD-9-CM 990 (effects radiation NOS). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.