2026 ICD-10-CM Diagnosis Code T65.91XSToxic effect of unspecified substance, accidental (unintentional), sequela

ICD-10-CM CodesS00–T88T51-T65T65

ICD-10-CM T65.91XS
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

T65.91XS is a billable ICD-10-CM diagnosis code for toxic effect of unspecified substance, accidental (unintentional), sequela. The 7th character S marks it as a sequela code, which reports a problem that remains after the original condition has resolved. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 922 through 923. The code is exempt from POA reporting. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Poisoning/toxic effect/adverse effects/underdosing, sequela.

Code Identity

ICD-10-CM Code
T65.91XS
Billable Status
Yes — Valid for Submission
Code Describes
Toxic effect of unspecified substance, accidental (unintentional), sequela
Short Description
Toxic effect of unsp substance, accidental, sequela
Parent Code
Toxic effect of unspecified substance, accidental (unintentional)

Code Classification

ChapterS00–T88Injury, poisoning and certain other consequences of external causes
SectionT51-T65Toxic effects of substances chiefly nonmedicinal as to source
CategoryT65Toxic effect of other and unspecified substances
This CodeT65.91XSToxic effect of unspecified substance, accidental (unintentional), sequela

Present on Admission (POA)Billing

T65.91XS is exempt from POA reporting on inpatient claims to general acute care hospitals. Review other POA exempt codes.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Accidental bismuth compound poisoning
  • Accidental ingestion of toxic substance
  • Accidental poisoning by household agents
  • Acne of external chemical origin
  • Acquired bronchiectasis
  • Acquired sensorineural hearing loss
  • Acute chemical bronchitis
  • Acute conjunctivitis caused by chemical
  • Acute conjunctivitis of bilateral eyes caused by chemical substance
  • Acute conjunctivitis of left eye caused by chemical substance
  • Acute conjunctivitis of right eye caused by chemical substance
  • Acute exogenous lipoid pneumonitis
  • Acute intoxication
  • Acute phototoxic reaction
  • Acute renal cortical necrosis
  • Acute toxic cicatrizing conjunctivitis
  • Acute toxic conjunctivitis
  • Acute toxic tracheobronchitis
  • Acute tracheitis
  • Acute tracheobronchitis
  • Acute tubular necrosis
  • Adverse effect of exposure to industrial hazardous material
  • Aerosol air freshener causing toxic effect
  • Air freshener causing toxic effect
  • Allergic reaction to chemical
  • Anagen effluvium
  • Bilateral acute conjunctivitis
  • Bismuth compound poisoning
  • Bronchiectasis due to aspiration of toxic substance
  • Bronchiectasis due to inhalation of toxic substance
  • Bronchitis caused by chemical
  • Burn and corrosion of hip and lower limb, except ankle and foot
  • Burn erythema of chest wall
  • Burn of abdominal wall
  • Burn of ankle and foot
  • Burn of breast
  • Burn of chin
  • Burn of conjunctival sac
  • Burn of conjunctival sac of left eye
  • Burn of conjunctival sac of right eye
  • Burn of cornea of left eye
  • Burn of cornea of right eye
  • Burn of dorsum of left hand
  • Burn of dorsum of right hand
  • Burn of esophagus
  • Burn of forehead
  • Burn of larynx
  • Burn of larynx and/or trachea
  • Burn of left ankle
  • Burn of left eye proper
  • Burn of left forearm
  • Burn of left knee region
  • Burn of left lower leg
  • Burn of left ocular adnexa
  • Burn of left palm
  • Burn of left thigh
  • Burn of left upper arm
  • Burn of nose
  • Burn of right ankle
  • Burn of right eye proper
  • Burn of right forearm
  • Burn of right knee region
  • Burn of right lower leg
  • Burn of right ocular adnexa
  • Burn of right palm
  • Burn of right thigh
  • Burn of right upper arm
  • Burn of scalp
  • Burn of throat
  • Burn of toe of left foot
  • Burn of toe of right foot
  • Burn of vagina
  • Burning caused by caustic organic chemical
  • Carcinogen effect
  • Cerebellar ataxia caused by chemical
  • Chemical burn injury to conjunctiva
  • Chemical burn of abdominal wall
  • Chemical burn of back of left hand
  • Chemical burn of back of right hand
  • Chemical burn of esophagus
  • Chemical burn of eyelid
  • Chemical burn of face
  • Chemical burn of forehead
  • Chemical burn of gastrointestinal tract
  • Chemical burn of hand
  • Chemical burn of head
  • Chemical burn of internal organ
  • Chemical burn of larynx
  • Chemical burn of left ankle
  • Chemical burn of left conjunctival sac
  • Chemical burn of left cornea
  • Chemical burn of left eye
  • Chemical burn of left foot
  • Chemical burn of left forearm
  • Chemical burn of left hand
  • Chemical burn of left knee
  • Chemical burn of left lower leg
  • Chemical burn of left palm
  • Chemical burn of left thigh
  • Chemical burn of left toe
  • Chemical burn of left upper arm
  • Chemical burn of mouth
  • Chemical burn of respiratory tract
  • Chemical burn of right ankle
  • Chemical burn of right conjunctival sac
  • Chemical burn of right cornea
  • Chemical burn of right eye
  • Chemical burn of right foot
  • Chemical burn of right forearm
  • Chemical burn of right hand
  • Chemical burn of right knee
  • Chemical burn of right lower leg
  • Chemical burn of right palm
  • Chemical burn of right thigh
  • Chemical burn of right toe
  • Chemical burn of right upper arm
  • Chemical burn of scalp
  • Chemical burn of skin
  • Chemical burn of toe
  • Chemical burn of vagina
  • Chemical colitis
  • Chemical cranial nerve injury
  • Chemical esophagitis
  • Chemical hematuria
  • Chemical injury to cornea
  • Chemical keratitis
  • Chemical meningitis
  • Chemical-aggravated angioedema-urticaria
  • Chemical-induced asthma
  • Chemical-induced dermatological disorder
  • Chemically-induced hypomelanosis
  • Chemically-induced malabsorption
  • Chemically-induced proctitis
  • Chronic chemical respiratory disease
  • Chronic exogenous lipoid pneumonitis
  • Chronic follicular conjunctivitis
  • Chronic myocardial disorder caused by chemical or external agent
  • Chronic poisoning
  • Chronic toxic cicatrizing conjunctivitis
  • Chronic toxic follicular conjunctivitis
  • Chronic toxic interstitial nephritis
  • Cicatrizing conjunctivitis
  • Cognitive impairment due to toxicity of substance
  • Correction fluid causing toxic effect
  • Corrosion of 2nd degree of hip and lower limb, except ankle and foot
  • Corrosion of ankle and foot
  • Corrosion of esophagus
  • Corrosion of first degree of ankle and foot
  • Corrosion of first degree of head and neck
  • Corrosion of first degree of hip and lower limb,except ankle and foot
  • Corrosion of first degree of trunk
  • Corrosion of first degree of wrist and hand
  • Corrosion of head and neck
  • Corrosion of larynx and/or trachea
  • Corrosion of second degree of ankle and foot
  • Corrosion of second degree of head and neck
  • Corrosion of second degree of shoulder and upper limb, except wrist and hand
  • Corrosion of second degree of trunk
  • Corrosion of second degree of wrist and hand
  • Corrosion of third degree of ankle and foot
  • Corrosion of third degree of head and neck
  • Corrosion of third degree of hip and lower limb, except ankle and foot
  • Corrosion of wrist and hand
  • Crayon causing toxic effect
  • Dabbing
  • Damp-proof liquid causing toxic effect
  • Diarrhea caused by ingestion of unabsorbable substances
  • Disorder due to and following accidental poisoning
  • Disorder due to and following poisoning
  • Disturbance of hair cycle
  • Drug ototoxicity - deafness
  • Duodenitis caused by chemical
  • Environmental toxin-induced male infertility
  • Epidermal burn of back
  • Epidermal burn of breast
  • Epidermal burn of chin
  • Epidermal burn of ear
  • Epidermal burn of neck
  • Epidermal burn of nose
  • Epidermal burn of scalp
  • Epidermal burn of wrist
  • Epidermal burn of wrist and hand
  • Exogenous lipoid pneumonitis
  • Fetal disorder caused by substance transmitted via placenta
  • Filler causing toxic effect
  • Fire extinguisher material causing toxic effect
  • Fire retardant causing toxic effect
  • Firelighter causing toxic effect
  • Focal segmental glomerulosclerosis
  • Focal segmental glomerulosclerosis caused by substance
  • Full thickness burn of forearm
  • Full thickness burn of head and neck
  • Full thickness burn of left forearm
  • Full thickness burn of neck
  • Full thickness burn of right forearm
  • Full thickness chemical burn of forearm
  • Full thickness chemical burn of left forearm
  • Full thickness chemical burn of right forearm
  • Gardening product causing toxic effect
  • Gastric ulcer caused by chemical
  • Hair shaft damage by chemical
  • Inflammatory and toxic neuropathy
  • Ingestion of foreign material
  • Ingestion of toxic substance
  • Inhalation injury
  • Inhalation injury due to chemical
  • Inhalation of substance
  • Injury due to chemical exposure
  • Injury to respiratory system due to inhalation of particulate matter
  • Intoxication
  • Keratitis due to trauma
  • Lipoid pneumonitis
  • Local toxic nerve damage
  • Lung disease due to external agents
  • Movement disorder due to toxicity of substance
  • Myelopathy due to toxicity of substance
  • Myocarditis due to chemical agent
  • Nail changes associated with systemic disease
  • Nail damage caused by chemical agents
  • Nail damage from external agent
  • Nail dystrophy caused by chemical
  • Neuropathy caused by chemical substance
  • Neuropathy caused by organic substance
  • Neurotoxicity
  • Non-infective diarrhea
  • Non-melanin pigmentation caused by exogenous substance
  • Occupational acne
  • Occupational phototoxic reaction to skin contact with exogenous photoactive agent
  • Occupational toxicoderma
  • Oil acne
  • Onycholysis
  • Onycholysis caused by chemical
  • Osmotic diarrhea
  • Ototoxic degeneration of cochlea
  • Ototoxicity
  • Ototoxicity - deafness
  • Ototoxicity - labyrinthine
  • Partial thickness burn of left foot
  • Partial thickness burn of right foot
  • Partial thickness burn of shoulder
  • Partial thickness burn of wrist
  • Pericarditis caused by toxin
  • Peripheral neuropathy caused by toxin
  • Peripheral neuropathy of upper limb caused by toxin
  • Pet animal-care product causing toxic effect
  • Photographic material causing toxic effect
  • Phototoxic reaction to topical chemical
  • Pigment nephropathy
  • Plaster of Paris injury to skin
  • Pneumonitis caused by inhaled substance
  • Pneumonitis caused by solids
  • Pneumonitis due to inhaled liquid
  • Poisoning
  • Porphyria caused by toxic effect of substance
  • Pulmonary arterial hypertension induced by toxin
  • Rust remover causing toxic effect
  • Sealant causing toxic effect
  • Second degree chemical burn of foot
  • Second degree chemical burn of left foot
  • Second degree chemical burn of right foot
  • Secondary porphyria
  • Self-administered accidental poisoning
  • Shoe care product causing toxic effect
  • Silo-fillers' disease
  • Skin reaction to vesicant poison
  • Small vessel pulmonary hypertension
  • Solitary pulmonary hypertension
  • Substance-induced ataxia
  • Sulfite-induced asthma
  • Superficial corrosion of back
  • Superficial corrosion of breast
  • Superficial corrosion of cheek
  • Superficial corrosion of chest wall
  • Superficial corrosion of chin
  • Superficial corrosion of ear
  • Superficial corrosion of lip
  • Superficial corrosion of neck
  • Superficial corrosion of nose
  • Superficial corrosion of scalp
  • Superficial injury of chin
  • Toxic acute tubular necrosis
  • Toxic amblyopia
  • Toxic anagen effluvium
  • Toxic cardiomyopathy
  • Toxic chorea
  • Toxic confusional state
  • Toxic deafness
  • Toxic dementia
  • Toxic dilatation of intestine
  • Toxic dilated cardiomyopathy
  • Toxic disorder of refraction AND/OR accommodation
  • Toxic dystonia
  • Toxic emphysema
  • Toxic enteritis of small intestine
  • Toxic gastritis
  • Toxic keratoconjunctivitis
  • Toxic leukoencephalopathy
  • Toxic optic neuropathy
  • Toxic polyneuropathy
  • Toxic radiculopathy
  • Toxic retinopathy
  • Toxic tremor
  • Toxicoderma
  • Toxin-induced bronchiectasis
  • Toxin-induced parkinsonism
  • Ulcer of duodenum caused by chemical
  • Ulcer of esophagus caused by ingestion of corrosive chemical
  • Vulvitis caused by chemical
  • Wallpaper stripper causing toxic effect

Coding GuidelinesGuidance

The appropriate 7th character is to be added to each code from block Toxic effect of other and unspecified substances (T65). Use the following options for the applicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INJ075
Poisoning/toxic effect/adverse effects/underdosing, sequela
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Salmonella Food Poisoning

    poisoning caused by ingestion of food harboring species of salmonella. conditions of raising, shipping, slaughtering, and marketing of domestic animals contribute to the spread of this bacterium in the food supply.
  • Poisoning

    a condition or physical state produced by the ingestion, injection, inhalation of or exposure to a deleterious agent.
  • Plant Poisoning

    poisoning by the ingestion of plants or its leaves, berries, roots or stalks. the manifestations in both humans and animals vary in severity from mild to life threatening. in animals, especially domestic animals, it is usually the result of ingesting moldy or fermented forage.
  • Organophosphate Poisoning

    poisoning due to exposure to organophosphorus compounds, such as organophosphates; organothiophosphates; and organothiophosphonates.
  • Neurotoxicity Syndromes

    neurologic disorders caused by exposure to toxic substances through ingestion, injection, cutaneous application, or other method. this includes conditions caused by biologic, chemical, and pharmaceutical agents.
  • Mycotoxicosis

    poisoning caused by the ingestion of mycotoxins (toxins of fungal origin).
  • Mushroom Poisoning

    poisoning from ingestion of mushrooms, primarily from, but not restricted to, toxic varieties.
  • MPTP Poisoning

    a condition caused by the neurotoxin mptp which causes selective destruction of nigrostriatal dopaminergic neurons. clinical features include irreversible parkinsonian signs including rigidity and bradykinesia (parkinson disease, secondary). mptp toxicity is also used as an animal model for the study of parkinson disease. (adams et al., principles of neurology, 6th ed, p1072; neurology 1986 feb;36(2):250-8)
  • Mercury Poisoning, Nervous System

    neurologic disorders associated with exposure to inorganic and organic forms of mercury. acute intoxication may be associated with gastrointestinal disturbances, mental status changes, and paraparesis. chronic exposure to inorganic mercury usually occurs in industrial workers, and manifests as mental confusion, prominent behavioral changes (including psychosis), dyskinesias, and neuritis. alkyl mercury poisoning may occur through ingestion of contaminated seafood or grain, and its characteristic features include polyneuropathy; ataxia; vision loss; nystagmus, pathologic; and deafness. (from joynt, clinical neurology, 1997, ch20, pp10-15)
  • Mercury Poisoning

    poisoning that results from chronic or acute ingestion, injection, inhalation, or skin absorption of mercury or mercury compounds.
  • Manganese Poisoning

    manganese poisoning is associated with chronic inhalation of manganese particles by individuals who work with manganese ore. clinical features include confusion; hallucinations; and an extrapyramidal syndrome (parkinson disease, secondary) that includes rigidity; dystonia; retropulsion; and tremor. (adams, principles of neurology, 6th ed, p1213)
  • Lead Poisoning, Nervous System, Childhood

    neurologic disorders occurring in children following lead exposure. the most frequent manifestation of childhood lead toxicity is an encephalopathy associated with chronic ingestion of lead that usually presents between the ages of 1 and 3 years. clinical manifestations include behavioral changes followed by lethargy; convulsions; hallucinations; delirium; ataxia; and vomiting. elevated intracranial pressure (hypertension, intracranial) and cerebral edema may occur. (from adams et al., principles of neurology, 6th ed, p1210-2)
  • Lead Poisoning, Nervous System, Adult

    neurologic conditions in adults associated with acute or chronic exposure to lead or any of its salts. the most common lead related neurologic syndrome in adults consists of a polyneuropathy involving motor fibers. this tends to affect distal nerves and may present as wrist drop due to radial neuropathy. additional features of chronic lead exposure include anemia; constipation; colicky abdominal pain; a bluish lead line of the gums; interstitial nephritis (nephritis, interstitial); and saturnine gout. an encephalopathy may rarely occur. (from adams et al., principles of neurology, 6th ed, p1212)
  • Lead Poisoning, Nervous System

    injury to the nervous system secondary to exposure to lead compounds. two distinct clinical patterns occur in children (lead poisoning, nervous system, childhood) and adults (lead poisoning, nervous system, adult). in children, lead poisoning typically produces an encephalopathy. in adults, exposure to toxic levels of lead is associated with a peripheral neuropathy.
  • Lead Poisoning

    poisoning that results from chronic or acute ingestion, injection, inhalation, or skin absorption of lead or lead compounds.
  • Heavy Metal Poisoning, Nervous System

    conditions associated with damage or dysfunction of the nervous system caused by exposure to heavy metals, which may cause a variety of central, peripheral, or autonomic nervous system injuries.
  • Heavy Metal Poisoning

    poisoning that results from chronic or acute ingestion, injection, inhalation, or skin absorption of heavy metals. acute and chronic exposures can cause anemia; kidney and liver damage; pulmonary edema; memory loss and behavioral changes; bone deformities in children; and miscarriage or premature labor in pregnant people.
  • Gas Poisoning

    poisoning that results from exposure to gases such as carbon monoxide; noble gases; oxygen; or natural gas.
  • Foodborne Diseases

    acute illnesses, usually affecting the gastrointestinal tract, brought on by consuming contaminated food or beverages. most of these diseases are infectious, caused by a variety of bacteria, viruses, or parasites that can be foodborne. sometimes the diseases are caused by harmful toxins from the microbes or other chemicals present in the food. especially in the latter case, the condition is often called food poisoning.
  • Toxic Optic Neuropathy

    damage to the eye or its function (e.g., visual impairment) due to optic nerve damage secondary to toxic substances such as drugs used in chemotherapy; immunotherapy; or radiation.
  • Aflatoxin Poisoning

    poisoning by aflatoxins most often associated with nausea, abdominal pain, hepatotoxicity, immunosuppression, hepatocellular carcinoma and sometimes death.
  • Arsenic Poisoning

    disorders associated with acute or chronic exposure to compounds containing arsenic (arsenicals) which may be fatal. acute oral ingestion is associated with gastrointestinal symptoms and an encephalopathy which may manifest as seizures, mental status changes, and coma. chronic exposure is associated with mucosal irritation, desquamating rash, myalgias, peripheral neuropathy, and white transverse (mees) lines in the fingernails. (adams et al., principles of neurology, 6th ed, p1212)
  • Cadmium Poisoning

    poisoning occurring after exposure to cadmium compounds or fumes. it may cause gastrointestinal syndromes, anemia, or pneumonitis.
  • Carbon Monoxide Poisoning

    toxic asphyxiation due to the displacement of oxygen from oxyhemoglobin by carbon monoxide.
  • Carbon Tetrachloride Poisoning

    poisoning that results from ingestion, injection, inhalation, or skin absorption of carbon tetrachloride.
  • Ciguatera Poisoning

    poisoning caused by ingestion of seafood containing microgram levels of ciguatoxins. the poisoning is characterized by gastrointestinal, neurological and cardiovascular disturbances.
  • Ergotism

    poisoning caused by ingesting ergotized grain or by the misdirected or excessive use of ergot as a medicine.
  • Fluoride Poisoning

    poisoning that results from chronic or acute ingestion, injection, inhalation, or skin absorption of fluoride compounds.
  • Sepsis

    systemic inflammatory response syndrome with a proven or suspected infectious etiology. when sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. when sepsis is accompanied by hypotension despite adequate fluid infusion, it is called septic shock.
  • Shellfish Poisoning

    poisoning from toxins present in bivalve mollusks that have been ingested. four distinct types of shellfish poisoning are recognized based on the toxin involved.
  • Staphylococcal Food Poisoning

    poisoning by staphylococcal toxins present in contaminated food.
  • Onycholysis

    separation of nail plate from the underlying nail bed. it can be a sign of skin disease, infection (such as onychomycosis) or tissue injury.
  • Ototoxicity

    damage to the ear or its function secondary to exposure to toxic substances such as drugs used in chemotherapy; immunotherapy; or radiation.
  • Carbon Tetrachloride

    a solvent for oils, fats, lacquers, varnishes, rubber waxes, and resins, and a starting material in the manufacturing of organic compounds. poisoning by inhalation, ingestion or skin absorption is possible and may be fatal. (merck index, 11th ed)
  • Gastrointestinal Tract

    generally refers to the digestive structures stretching from the mouth to anus, but does not include the accessory glandular organs (liver; biliary tract; pancreas).
  • Lead

    a soft, grayish metal with poisonous salts; atomic number 82, atomic weight 207.2, symbol pb.
  • Salmonella

    a genus of gram-negative, facultatively anaerobic, rod-shaped bacteria that utilizes citrate as a sole carbon source. it is pathogenic for humans, causing enteric fevers, gastroenteritis, and bacteremia. food poisoning is the most common clinical manifestation. organisms within this genus are separated on the basis of antigenic characteristics, sugar fermentation patterns, and bacteriophage susceptibility.
  • Onychomycosis

    a fungal infection of the nail, usually caused by dermatophytes; yeasts; or nondermatophyte molds.
  • Chronic Follicular Conjunctivitis

    follicular conjunctivitis caused by chlamydia trachomatis, moraxella, borrelia, molluscum contagiosum, or toxicity from eye make-up and eye drops.
  • Chronic Toxic Polyneuropathy

    neuropathy affecting multiple nerves that is caused by prolonged exposure to toxic substances.
  • Athanasia trifurcata Poisoning|Athanasia trifurcata poisoning

    toxicity resulting exposure to the athanasia trifurcata plant.
  • Common Cold Medication Poisoning|Anti-common cold drug poisoning

    toxicity resulting from overconsumption or abuse of common cold medication.
  • Demeton Poisoning|Demeton poisoning

    poisoning due to exposure to the organophosphate insecticide, demeton.
  • Dicentra Species Poisoning|Dicentra species poisoning

    poisoning due to exposure to the species of the plant genus, dicentra.
  • Solanum nigrum Poisoning|Solanum nigrum poisoning

    poisoning resulting from consuming solanum nigrum, black nightshade.
  • Toad Toxin Poisoning|Toad Toxicosis|Toad poisoning

    human poisoning due to exposure to toad toxins.
  • Anagen Effluvium

    non-scarring alopecia arising during the growth (anagen) phase of the hair cycle. it may be associated with chemotherapy, exposure to radiation or heavy metals, poor nutrition, or various autoimmune conditions.
  • Toxic Amblyopia

    amblyopia due to exposure to a toxin.
  • Profenamine Poisoning|Ethopropazine poisoning

    poisoning due to overexposure to profenamine, a medication used to treat parkinson disease and the extrapyramidal signs associated with certain antipsychotic medications.
  • Phosdrin Poisoning|Toxic effect of phosdrin

    toxic effects of phosdrin exposure.
  • Peganum harmala Poisoning|Peganum harmala poisoning

    poisoning by the seeds of the peganum harmala plant, which is a traditional medicine used as to treat menstrual flow or aid in abortion.
  • Oxytocin Poisoning|Oxytocin poisoning

    excessive amounts of oxytocin in the body.
  • Osteospermum Species Poisoning|Osteospermum species poisoning

    poisoning by inhalation, ingestion or dermal contact with members of the osteospermum species.
  • Orciprenaline Poisoning|Orciprenaline poisoning

    deleterious effects due to excessive amounts of the bronchodilator metaproterenol in an individual.
  • Nitrofuran Derivative Poisoning|Nitrofuran derivative poisoning

    poisoning by a derivative of nitrofuran.
  • Moraea Species Poisoning|Homeria Species Poisoning|Homeria species poisoning

    poisoning due to ingestion of the toxic cardiac glycosides found in plants belonging to species of the moraea (formerly homeria) genus.
  • Injury, Poisoning and Procedural Complications, CTCAE 6.0

    injury, poisoning and procedural complications captures adverse events effecting this system organ class as defined and used by meddra and ctcae 6.0.
  • Injury, Poisoning and Procedural Complications - Other, Specify, CTCAE|Injury, Poisoning and Procedural Complications - Other|Injury, poisoning and procedural complications - Other, specify

    other specified types of injury, poisoning and procedural complications.
  • Grade 3 Injury, Poisoning and Procedural Complications - Other, Specify, CTCAE|Grade 3 Injury, poisoning and procedural complications - Other, specify

    severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self-care adl or severe impact on age-appropriate normal daily activity (pediatric)
  • Grade 2 Injury, Poisoning and Procedural Complications - Other, Specify, CTCAE|Grade 2 Injury, poisoning and procedural complications - Other, specify

    moderate; minimal, local or noninvasive intervention indicated; limiting instrumental adl or mild/moderate impact on age-appropriate normal daily activity (pediatric)
  • Encephalartos Species Poisoning|Cycad Poisoning|Encephalartos species poisoning

    poisoning due to exposure to the species of the plant genus, encephalartos.
  • Alcohol Abuse with Intoxication Delirium|Alcohol abuse with intoxication delirium

    evidence of alcohol abuse with intoxication delirium.
  • Alcohol Abuse with Intoxication, Uncomplicated|Alcohol abuse with intoxication, uncomplicated

    evidence of alcohol abuse with intoxication, uncomplicated.
  • Alcohol Abuse with Intoxication, Unspecified|Alcohol abuse with intoxication, unspecified

    evidence of alcohol abuse with intoxication.
  • Alcohol Dependence with Intoxication Delirium|Alcohol dependence with intoxication delirium

    evidence of alcohol dependence with intoxication delirium.
  • Alcohol Dependence with Intoxication, Uncomplicated|Alcohol dependence with intoxication, uncomplicated

    evidence of alcohol dependence with intoxication, uncomplicated.
  • Alcohol Dependence with Intoxication, Unspecified|Alcohol dependence with intoxication, unspecified

    evidence of alcohol dependence with intoxication.
  • Alcohol Intoxication

    disturbances in psychophysiological functions and responses as a result of consumption of a beverage containing ethanol.
  • Barbiturate Intoxication

    disturbances in psychophysiological functions and responses as a result of administration or ingestion of a member of the barbiturate class of central nervous system depressants.
  • Cannabis Abuse with Intoxication Delirium|Cannabis abuse with intoxication delirium

    evidence of cannabis abuse with intoxication delirium.
  • Cannabis Abuse with Intoxication with Perceptual Disturbance|Cannabis abuse with intoxication with perceptual disturbance

    evidence of cannabis abuse with intoxication with perceptual disturbance.
  • Cannabis Abuse with Intoxication, Uncomplicated|Cannabis abuse with intoxication, uncomplicated

    evidence of cannabis abuse with intoxication, uncomplicated.
  • Cannabis Abuse with Intoxication, Unspecified|Cannabis abuse with intoxication, unspecified

    evidence of cannabis abuse with intoxication.
  • Cannabis Dependence with Intoxication Delirium|Cannabis dependence with intoxication delirium

    evidence of cannabis dependence with intoxication delirium.
  • Cannabis Dependence with Intoxication with Perceptual Disturbance|Cannabis dependence with intoxication with perceptual disturbance

    evidence of cannabis dependence with intoxication with perceptual disturbance.
  • Cannabis Dependence with Intoxication, Uncomplicated|Cannabis dependence with intoxication, uncomplicated

    evidence of cannabis dependence with intoxication, uncomplicated.
  • Cannabis Dependence with Intoxication, Unspecified|Cannabis dependence with intoxication, unspecified

    evidence of cannabis dependence with intoxication.
  • Child Intoxication With Breast Implant Material Ingredients|Toxins In Children

    children affected by toxins may be due to silicone breast implants and their effects on unborn children and from breastfeeding.
  • Onycholysis

    a nail condition characterized by spontaneous separation of a fingernail or toenail from its nail bed.
  • Ototoxicity

    damage to the inner ear as a result of exposure to drugs or chemicals.
  • Phototoxicity Study|PHOTOTOXICITY

    a study of the effect of an agent on the skin or eyes, such that it induces a sensitivity to sunlight or other forms of light.
  • Phototoxicity|phototoxicity

    a nonimmunologic, chemically induced type of photosensitivity.
  • Nail Loss, PRO-CTCAE|Nail loss|Onycholysis, PRO-CTCAE|PRO-CTCAE, Nail Loss

    onycholysis as recorded on the pro-ctcae questionnaire.
  • Staphylococcal Food Poisoning

    food poisoning that is caused by staphylococcal infection.
  • Septicemia|Sepsis|Sepsis|Sepsis|Sepsis|Sepsis Syndrome|Systemic Sepsis|blood poisoning|sepsis|septicemia|toxemia

    the presence of pathogenic microorganisms in the blood stream causing a rapidly progressing systemic reaction that may lead to shock. symptoms include fever, chills, tachycardia, and increased respiratory rate. it is a medical emergency that requires urgent medical attention.
  • Poisoning

    injury to the body or interference of normal body functions by a substance that is swallowed, inhaled, injected, or absorbed.
  • Lead Poisoning

    chronic toxicity to the body caused by the absorption of lead, which is characterized by fatigue, gastrointestinal symptoms, anemia, a dark line along the gums, and muscular paralysis or weakness of limbs.
  • Injury, Poisoning and Procedural Complication Class

    a class of disorders that encompasses conditions resulting from an injury, poisoning or procedure.
  • Grade 5 Injury, Poisoning and Procedural Complications - Other, Specify, CTCAE|Grade 5 Injury, poisoning and procedural complications - Other, specify

    death
  • Grade 4 Injury, Poisoning and Procedural Complications - Other, Specify, CTCAE|Grade 4 Injury, poisoning and procedural complications - Other, specify

    life-threatening consequences; urgent intervention indicated
  • Grade 3 Injury, Poisoning and Procedural Complications - Other, Specify, CTCAE|Grade 3 Injury, poisoning and procedural complications - Other, specify

    severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self care adl
  • Grade 2 Injury, Poisoning and Procedural Complications - Other, Specify, CTCAE|Grade 2 Injury, poisoning and procedural complications - Other, specify

    moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental adl
  • Grade 1 Injury, Poisoning and Procedural Complications - Other, Specify, CTCAE|Grade 1 Injury, poisoning and procedural complications - Other, specify

    asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated
  • Foodborne Illness|Food Poisoning

    any disorder that results from the consumption of food contaminated with an infectious agent or toxin.
  • Ischemic Nephropathy

    nephropathy due to hypoperfusion of the kidney.
  • Burn of Esophagus

    thermal or caustic injury to the esophagus.
  • Toxic Polyneuropathy

    polyneuropathy that is caused by exposure to toxins.
  • Substance Intoxication Delirium

    a disorder characterized by the acute and sudden development of changes in attention, memory, language and/or perception that can be etiologically linked to the direct physiological consequences of substance intoxication.
  • Sedative, Hypnotic or Anxiolytic Induced Dependence with Intoxication, Unspecified|Sedative, hypnotic or anxiolytic induced dependence with intoxication, unspecified

    evidence of sedative, hypnotic or anxiolytic induced dependence with intoxication.
  • Sedative, Hypnotic or Anxiolytic Induced Dependence with Intoxication, Uncomplicated|Sedative, hypnotic or anxiolytic induced dependence with intoxication, uncomplicated

    evidence of sedative, hypnotic or anxiolytic induced dependence with intoxication, uncomplicated.
  • Sedative, Hypnotic or Anxiolytic Induced Dependence with Intoxication Delirium|Sedative, hypnotic or anxiolytic induced dependence with intoxication delirium

    evidence of sedative, hypnotic or anxiolytic induced dependence with intoxication delirium.
  • Sedative, Hypnotic or Anxiolytic Abuse with Intoxication, Unspecified|Sedative, hypnotic or anxiolytic abuse with intoxication, unspecified

    evidence of sedative, hypnotic or anxiolytic abuse with intoxication.
  • Sedative, Hypnotic or Anxiolytic Abuse with Intoxication, Uncomplicated|Sedative/hypnotic/anxiolytic abuse with intoxication, uncomplicated

    evidence of sedative, hypnotic or anxiolytic abuse with intoxication, uncomplicated.
  • Sedative, Hypnotic or Anxiolytic Abuse with Intoxication Delirium|Sedative/hypnotic/anxiolytic abuse with intoxication delirium

    evidence of sedative, hypnotic or anxiolytic abuse with intoxication delirium.
  • Other Stimulant Dependence with Intoxication, Unspecified|Other stimulant dependence with intoxication, unspecified

    evidence of other stimulant dependence with intoxication not specified elsewhere.
  • Other Stimulant Dependence with Intoxication, Uncomplicated|Other stimulant dependence with intoxication, uncomplicated

    evidence of other uncomplicated stimulant dependence with intoxication that is not specified elsewhere.
  • Other Stimulant Dependence with Intoxication with Perceptual Disturbance|Other stimulant dependence with intoxication with perceptual disturbance

    evidence of other stimulant dependence with intoxication with perceptual disturbance not specified elsewhere.
  • Other Stimulant Dependence with Intoxication Delirium|Other stimulant dependence with intoxication delirium

    evidence of other stimulant dependence with intoxication delirium not specified elsewhere.
  • Other Stimulant Abuse with Intoxication, Unspecified|Other stimulant abuse with intoxication, unspecified

    evidence of other stimulant abuse with intoxication not specified elsewhere.
  • Other Stimulant Abuse with Intoxication, Uncomplicated|Other stimulant abuse with intoxication, uncomplicated

    evidence of other stimulant abuse with intoxication, uncomplicated not specified elsewhere.
  • Other Stimulant Abuse with Intoxication with Perceptual Disturbance|Other stimulant abuse with intoxication with perceptual disturbance

    evidence of other stimulant abuse with intoxication with perceptual disturbance not specified elsewhere.
  • Other Stimulant Abuse with Intoxication Delirium|Other stimulant abuse with intoxication delirium

    evidence of other stimulant abuse with intoxication delirium not specified elsewhere.
  • Other Psychoactive Substance Dependence with Intoxication, Unspecified|Other psychoactive substance dependence with intoxication, unspecified

    evidence of other psychoactive substance dependence with intoxication not specified elsewhere.
  • Other Psychoactive Substance Dependence with Intoxication, Uncomplicated|Other psychoactive substance dependence with intoxication, uncomplicated

    evidence of other psychoactive substance dependence with intoxication, uncomplicated not specified elsewhere.
  • Other Psychoactive Substance Dependence with Intoxication with Perceptual Disturbance|Other psychoactive substance dependence with intoxication with perceptual disturbance

    evidence of other psychoactive substance dependence with intoxication with perceptual disturbance not specified elsewhere.
  • Other Psychoactive Substance Dependence with Intoxication Delirium|Other psychoactive substance dependence with intoxication delirium

    evidence of other psychoactive substance dependence with intoxication delirium not specified elsewhere.
  • Other Psychoactive Substance Abuse with Intoxication, Unspecified|Other psychoactive substance abuse with intoxication, unspecified

    evidence of other psychoactive substance abuse with intoxication not specified elsewhere.
  • Other Psychoactive Substance Abuse with Intoxication, Uncomplicated|Other psychoactive substance abuse with intoxication, uncomplicated

    evidence of other psychoactive substance abuse with intoxication, uncomplicated not specified elsewhere.
  • Other Psychoactive Substance Abuse with Intoxication with Perceptual Disturbance|Other psychoactive substance abuse with intoxication with perceptual disturbance

    evidence of other psychoactive substance abuse with intoxication with perceptual disturbance not specified elsewhere.
  • Other Psychoactive Substance Abuse with Intoxication Delirium|Other psychoactive substance abuse with intoxication delirium

    evidence of other psychoactive substance abuse with intoxication delirium not specified elsewhere.
  • Opioid Dependence with Intoxication, Unspecified|Opioid dependence with intoxication, unspecified

    evidence of opioid dependence with intoxication.
  • Opioid Dependence with Intoxication, Uncomplicated|Opioid dependence with intoxication, uncomplicated

    evidence of opioid dependence with intoxication, uncomplicated.
  • Opioid Dependence with Intoxication with Perceptual Disturbance|Opioid dependence with intoxication with perceptual disturbance

    evidence of opioid dependence with intoxication with perceptual disturbance.
  • Opioid Dependence with Intoxication Delirium|Opioid dependence with intoxication delirium

    evidence of opioid dependence with intoxication delirium.
  • Opioid Abuse with Intoxication, Unspecified|Opioid abuse with intoxication, unspecified

    evidence of opioid abuse with intoxication.
  • Opioid Abuse with Intoxication, Uncomplicated|Opioid abuse with intoxication, uncomplicated

    evidence of opioid abuse with intoxication, uncomplicated.
  • Opioid Abuse with Intoxication with Perceptual Disturbance|Opioid abuse with intoxication with perceptual disturbance

    evidence of opioid abuse with intoxication with perceptual disturbance.
  • Opioid Abuse with Intoxication Delirium|Opioid abuse with intoxication delirium

    evidence of opioid abuse with intoxication delirium.
  • Intoxication

    disturbances in psychophysiological functions and responses as a result of administration or ingestion of a psychoactive substance.
  • Inhalant Dependence with Intoxication, Unspecified|Inhalant dependence with intoxication, unspecified

    evidence of inhalant dependence with intoxication.
  • Inhalant Dependence with Intoxication, Uncomplicated|Inhalant dependence with intoxication, uncomplicated

    evidence of inhalant dependence with intoxication, uncomplicated.
  • Inhalant Dependence with Intoxication Delirium|Inhalant dependence with intoxication delirium

    evidence of inhalant dependence with intoxication delirium.
  • Inhalant Abuse with Intoxication, Unspecified|Inhalant abuse with intoxication, unspecified

    evidence of inhalant abuse with intoxication.
  • Inhalant Abuse with Intoxication, Uncomplicated|Inhalant abuse with intoxication, uncomplicated

    evidence of inhalant abuse with intoxication, uncomplicated.
  • Inhalant Abuse with Intoxication Delirium|Inhalant abuse with intoxication delirium

    evidence of inhalant abuse with intoxication delirium.
  • Hallucinogen Dependence with Intoxication, Unspecified|Hallucinogen dependence with intoxication, unspecified

    evidence of hallucinogen dependence with intoxication.
  • Hallucinogen Dependence with Intoxication, Uncomplicated|Hallucinogen dependence with intoxication, uncomplicated

    evidence of hallucinogen dependence with intoxication, uncomplicated.
  • Hallucinogen Dependence with Intoxication with Delirium|Hallucinogen dependence with intoxication with delirium

    evidence of hallucinogen dependence with intoxication with delirium.
  • Hallucinogen Abuse with Intoxication, Unspecified|Hallucinogen abuse with intoxication, unspecified

    evidence of hallucinogen abuse with intoxication.
  • Hallucinogen Abuse with Intoxication, Uncomplicated|Hallucinogen abuse with intoxication, uncomplicated

    evidence of hallucinogen abuse with intoxication, uncomplicated.
  • Hallucinogen Abuse with Intoxication with Perceptual Disturbance|Hallucinogen abuse with intoxication with perceptual disturbance

    evidence of hallucinogen abuse with intoxication with perceptual disturbance.
  • Hallucinogen Abuse with Intoxication with Delirium|Hallucinogen abuse with intoxication with delirium

    evidence of hallucinogen abuse with intoxication with delirium.
  • Cocaine Dependence with Intoxication, Unspecified|Cocaine dependence with intoxication, unspecified

    evidence of cocaine dependence with intoxication.
  • Cocaine Dependence with Intoxication, Uncomplicated|Cocaine dependence with intoxication, uncomplicated

    evidence of cocaine dependence with intoxication, uncomplicated.
  • Cocaine Dependence with Intoxication with Perceptual Disturbance|Cocaine dependence with intoxication with perceptual disturbance

    evidence of cocaine dependence with intoxication with perceptual disturbance.
  • Cocaine Dependence with Intoxication Delirium|Cocaine dependence with intoxication delirium

    evidence of cocaine dependence with intoxication delirium.
  • Cocaine Abuse with Intoxication, Unspecified|Cocaine abuse with intoxication, unspecified

    evidence of cocaine abuse with intoxication.
  • Cocaine Abuse with Intoxication, Uncomplicated|Cocaine abuse with intoxication, uncomplicated

    evidence of cocaine abuse with intoxication, uncomplicated.
  • Cocaine Abuse with Intoxication with Perceptual Disturbance|Cocaine abuse with intoxication with perceptual disturbance

    evidence of cocaine abuse with intoxication with perceptual disturbance.
  • Cocaine Abuse with Intoxication with Delirium|Cocaine abuse with intoxication with delirium

    evidence of cocaine abuse with intoxication with delirium.

Table of Drugs and ChemicalsClinical

Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.

SubstanceAccidentalSelf-harmAssaultUndeter­minedAdverse
Effect
Under­dosing
Aerosol spray NECT65.91T65.92T65.93T65.94
Agricultural agent NECT65.91T65.92T65.93T65.94
Air contaminant (s), source/type NOST65.91T65.92T65.93T65.94
AntifreezeT65.91T65.92T65.93T65.94
Antifreeze::alcoholT65.91T65.92T65.93T65.94
Antifreeze::ethylene glycolT65.91T65.92T65.93T65.94
Chemical substance NECT65.91T65.92T65.93T65.94
Horticulture agent NECT65.91T65.92T65.93T65.94
Horticulture agent NEC::with pesticideT65.91T65.92T65.93T65.94
Ingested substance NECT65.91T65.92T65.93T65.94
Poison NECT65.91T65.92T65.93T65.94
Solid substanceT65.91T65.92T65.93T65.94
Solid substance::specified NECT65.91T65.92T65.93T65.94
Spray (aerosol)T65.91T65.92T65.93T65.94
Spray (aerosol)::cosmeticT65.91T65.92T65.93T65.94
Spray (aerosol)::medicinal NECT65.91T65.92T65.93T65.94
Spray (aerosol)::pesticidesT65.91T65.92T65.93T65.94
Spray (aerosol)::specified contentT65.91T65.92T65.93T65.94

Patient EducationClinical

Poisoning

A poison is any substance that is harmful to your body. You might swallow it, inhale it, inject it, or absorb it through your skin. Any substance can be poisonous if too much is taken. Poisons can include:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert T65.91XS to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
909.1 Late eff nonmed substanc
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.
ICD-9-CM
E929.2 Late eff acc poisoning
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About T65.91XSOverview

Is T65.91XS a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report toxic effect of unspecified substance, accidental (unintentional), sequela on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What does the 7th character S in T65.91XS mean?

The final character S makes this a sequela code: it reports a lingering problem that remains after the toxic effect of unspecified substance, accidental (unintentional) itself has resolved, not the original event.

What MS-DRG does T65.91XS group to?

When toxic effect of unspecified substance, accidental (unintentional), sequela is the principal diagnosis on an inpatient stay, it groups to MS-DRG 922, 923, with relative weights from 1.0177 to 1.7494 depending on complications. Higher weights mean higher Medicare reimbursement.

Is T65.91XS exempt from POA reporting?

Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for toxic effect of unspecified substance, accidental (unintentional), sequela on inpatient claims.

What is the ICD-9 equivalent of T65.91XS?

Under the General Equivalence Mappings, toxic effect of unspecified substance, accidental (unintentional), sequela converts to ICD-9-CM 909.1 (late eff nonmed substanc) and E929.2 (late eff acc poisoning). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.