2027 ICD-10-CM Diagnosis Code T65.844AToxic effect of xylazine, undetermined, initial encounter
T65.844A is a billable ICD-10-CM diagnosis code for toxic effect of xylazine, undetermined, initial encounter. The 7th character A marks it as an initial encounter code, used while the patient is receiving active treatment. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 917 through 918. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under External cause codes: intent of injury, undetermined; External cause codes: poisoning by drug; and Toxic effects, initial encounter.
Code Identity
Code Classification
Coding GuidelinesGuidance
The appropriate 7th character is to be added to each code from block Toxic effect of other and unspecified substances (T65). Use the following options for the applicable episode of care:
- A - initial encounter
- D - subsequent encounter
- S - sequela
Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2027, published by CMS and the National Center for Health Statistics.
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to T65.844A: its own notes plus those printed at T65.84, T65, block T51-T65, and Chapter 19. A note printed at a category, block or chapter applies to every code under it.
Excludes1
Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.
- contact with and (suspected) exposure to toxic substances (Z77.-)
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
Use Additional Code
Add a second code, after this one, to fully describe the condition.
- code to identify any retained foreign body, if applicable (Z18.-)
Notes
General instructions on how these codes are used.
- When no intent is indicated code to accidental. Undetermined intent is only for use when there is specific documentation in the record that the intent of the toxic effect cannot be determined.
- Use secondary code(s) from Chapter 20, External causes of morbidity, to indicate cause of injury. Codes within the T section that include the external cause do not require an additional external cause code
- The chapter uses the S-section for coding different types of injuries related to single body regions and the T-section to cover injuries to unspecified body regions as well as poisoning and certain other consequences of external causes.
7th Character
Every code in the category takes a 7th character from the listed values, with the placeholder X filling any empty positions before it.
- The appropriate 7th character is to be added to each code from category T65
- Ainitial encounter this code
- Dsubsequent encounter
- Ssequela
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Xylazine
an adrenergic alpha-2 agonist used as a sedative, analgesic and centrally acting muscle relaxant in veterinary medicine.
Table of Drugs and ChemicalsClinical
Patient EducationClinical
Poisoning
A poison is any substance that is harmful to your body. You might swallow it, inhale it, inject it, or absorb it through your skin. Any substance can be poisonous if too much is taken. Poisons can include:
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Code History & ChangesHistory
Replacement T65.844A replaces the following previously assigned code(s):
- T65.894A - Toxic effect of oth substances, undetermined, init encntr
Questions About T65.844AOverview
What is the ICD-10 code for toxic effect of xylazine, undetermined, initial encounter?
The ICD-10-CM code for toxic effect of xylazine, undetermined, initial encounter is T65.844A (sometimes written as T65844A). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is T65.844A (Toxic effect of xylazine, undetermined) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report toxic effect of xylazine, undetermined, initial encounter on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What does the 7th character A in T65.844A mean?
The final character A marks the initial encounter: use it while the patient is receiving active treatment for toxic effect of xylazine, undetermined, such as an emergency visit or first evaluation.
What MS-DRG does T65.844A group to?
When toxic effect of xylazine, undetermined, initial encounter is the principal diagnosis on an inpatient stay, it groups to MS-DRG 918, 917, with relative weights from 0.8716 to 1.5698 depending on complications. Higher weights mean higher Medicare reimbursement.
Can T65.844A be reported with a code from Z77?
Not as a rule. The Excludes1 note at block T51-T65, which applies to T65.844A, lists "contact with and (suspected) exposure to toxic substances (Z77.-)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).
