2026 ICD-10-CM Diagnosis Code T65.3X4AToxic effect of nitroderivatives and aminoderivatives of benzene and its homologues, undetermined, initial encounter

ICD-10-CM CodesS00–T88T51-T65T65

ICD-10-CM T65.3X4A
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

T65.3X4A is a billable ICD-10-CM diagnosis code for toxic effect of nitroderivatives and aminoderivatives of benzene and its homologues, undetermined, initial encounter. The 7th character A marks it as an initial encounter code, used while the patient is receiving active treatment. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 917 through 918. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under External cause codes: intent of injury, undetermined; External cause codes: poisoning by non-drug; and Toxic effects, initial encounter.

Code Identity

ICD-10-CM Code
T65.3X4A
Billable Status
Yes — Valid for Submission
Code Describes
Toxic effect of nitroderivatives and aminoderivatives of benzene and its homologues, undetermined, initial encounter
Short Description
Toxic eff of nitrodrv/aminodrv of benzn/homolog, undet, init
Parent Code
Toxic effect of nitroderivatives and aminoderivatives of benzene and its homologues, undetermined

Code Classification

ChapterS00–T88Injury, poisoning and certain other consequences of external causes
SectionT51-T65Toxic effects of substances chiefly nonmedicinal as to source
CategoryT65Toxic effect of other and unspecified substances
This CodeT65.3X4AToxic effect of nitroderivatives and aminoderivatives of benzene and its homologues, undetermined, initial encounter

Coding GuidelinesGuidance

The appropriate 7th character is to be added to each code from block Toxic effect of other and unspecified substances (T65). Use the following options for the applicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR EXT023
External cause codes: intent of injury, undetermined
Default principal diagnosis: inpatient No · outpatient No
CCSR EXT015
External cause codes: poisoning by non-drug
Default principal diagnosis: inpatient No · outpatient No
CCSR INJ023
Toxic effects, initial encounter
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Diphenylamine

    in humans it may be irritating to mucous membranes. methemoglobinemia has been produced experimentally. in veterinary use, it is one of active ingredients in topical agents for prevention and treatment of screwworm infestation. an indicator in tests for nitrate poisoning.

Table of Drugs and ChemicalsClinical

Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.

SubstanceAccidentalSelf-harmAssaultUndeter­minedAdverse
Effect
Under­dosing
Aniline (dye) (liquid)T65.3X1T65.3X2T65.3X3T65.3X4
Aniline (dye) (liquid)::analgesicT65.3X1T65.3X2T65.3X3T65.3X4
Aniline (dye) (liquid)::derivatives, therapeutic NECT65.3X1T65.3X2T65.3X3T65.3X4
Aniline (dye) (liquid)::vaporT65.3X1T65.3X2T65.3X3T65.3X4
AnisidineT65.3X1T65.3X2T65.3X3T65.3X4
Azobenzene smokeT65.3X1T65.3X2T65.3X3T65.3X4
Azobenzene smoke::acaricideT65.3X1T65.3X2T65.3X3T65.3X4
BenzenamineT65.3X1T65.3X2T65.3X3T65.3X4
BinitrobenzolT65.3X1T65.3X2T65.3X3T65.3X4
DichlorbenzidineT65.3X1T65.3X2T65.3X3T65.3X4
DinitrobenzeneT65.3X1T65.3X2T65.3X3T65.3X4
Dinitrobenzene::vaporT65.3X1T65.3X2T65.3X3T65.3X4
DinitrobenzolT65.3X1T65.3X2T65.3X3T65.3X4
Dinitrobenzol::vaporT65.3X1T65.3X2T65.3X3T65.3X4
DinitrobutylphenolT65.3X1T65.3X2T65.3X3T65.3X4
Dinitro (-ortho-)cresol (pesticide) (spray)T65.3X1T65.3X2T65.3X3T65.3X4
DinitrocyclohexylphenolT65.3X1T65.3X2T65.3X3T65.3X4
DinitrophenolT65.3X1T65.3X2T65.3X3T65.3X4
DiphenylamineT65.3X1T65.3X2T65.3X3T65.3X4
DNOCT65.3X1T65.3X2T65.3X3T65.3X4
DynamiteT65.3X1T65.3X2T65.3X3T65.3X4
Dynamite::fumesT65.3X1T65.3X2T65.3X3T65.3X4
MethoxyanilineT65.3X1T65.3X2T65.3X3T65.3X4
NitramineT65.3X1T65.3X2T65.3X3T65.3X4
NitroanilineT65.3X1T65.3X2T65.3X3T65.3X4
Nitroaniline::vaporT65.3X1T65.3X2T65.3X3T65.3X4
Nitrobenzene, nitrobenzolT65.3X1T65.3X2T65.3X3T65.3X4
Nitrobenzene, nitrobenzol::vaporT65.3X1T65.3X2T65.3X3T65.3X4
NitrodiphenylT65.3X1T65.3X2T65.3X3T65.3X4
NitrosodimethylamineT65.3X1T65.3X2T65.3X3T65.3X4
Nitrotoluene, nitrotoluolT65.3X1T65.3X2T65.3X3T65.3X4
Nitrotoluene, nitrotoluol::vaporT65.3X1T65.3X2T65.3X3T65.3X4
PhenylenediamineT65.3X1T65.3X2T65.3X3T65.3X4
TetrylT65.3X1T65.3X2T65.3X3T65.3X4
TNT (fumes)T65.3X1T65.3X2T65.3X3T65.3X4
ToluylenediamineT65.3X1T65.3X2T65.3X3T65.3X4
TrinitrobenzolT65.3X1T65.3X2T65.3X3T65.3X4
TrinitrophenolT65.3X1T65.3X2T65.3X3T65.3X4
Trinitrotoluene (fumes)T65.3X1T65.3X2T65.3X3T65.3X4

Patient EducationClinical

Poisoning

A poison is any substance that is harmful to your body. You might swallow it, inhale it, inject it, or absorb it through your skin. Any substance can be poisonous if too much is taken. Poisons can include:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert T65.3X4A to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
982.0 Toxic effect benzene
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.
ICD-9-CM
E980.9 Undeter pois-sol/liq NEC
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About T65.3X4AOverview

Is T65.3X4A a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report toxic effect of nitroderivatives and aminoderivatives of benzene and its homologues, undetermined, initial encounter on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What does the 7th character A in T65.3X4A mean?

The final character A marks the initial encounter: use it while the patient is receiving active treatment for toxic effect of nitroderivatives and aminoderivatives of benzene and its homologues, undetermined, such as an emergency visit or first evaluation.

What MS-DRG does T65.3X4A group to?

When toxic effect of nitroderivatives and aminoderivatives of benzene and its homologues, undetermined, initial encounter is the principal diagnosis on an inpatient stay, it groups to MS-DRG 917, 918, with relative weights from 0.8571 to 1.5684 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of T65.3X4A?

Under the General Equivalence Mappings, toxic effect of nitroderivatives and aminoderivatives of benzene and its homologues, undetermined, initial encounter converts to ICD-9-CM 982.0 (toxic effect benzene) and E980.9 (undeter pois-sol/liq NEC). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.