ICD-10 Code T45.8X5D

Adverse effect of prim systemic and hematolog agents, subs

Diagnosis Code T45.8X5D

ICD-10: T45.8X5D
Short Description: Adverse effect of prim systemic and hematolog agents, subs
Long Description: Adverse effect of other primarily systemic and hematological agents, subsequent encounter
Version 2019 of the ICD-10-CM diagnosis code T45.8X5D

Valid for Submission
The code T45.8X5D is valid for submission for HIPAA-covered transactions.

Deleted Code
This code was deleted in the 2019 ICD-10 code set with the code(s) listed below. The National Center for Health Statistics (NCHS) has published an update to the ICD-10-CM diagnosis codes which became effective October 1, 2018. This code was replaced for the FY 2019 (October 1, 2018 - September 30, 2019).
  • K59.03 - Drug induced constipation

Code Classification
  • Injury, poisoning and certain other consequences of external causes (S00–T98)
    • Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances (T36-T50)
      • Primarily systemic and hematological agents, NEC (T45)
Version 2019 Replaced Code Billable Code Unacceptable Principal Diagnosis POA Exempt

Information for Medical Professionals

Code Edits
The following edits are applicable to this code:
Unacceptable principal diagnosis - There are selected codes that describe a circumstance which influences an individual’s health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Convert to ICD-9
  • V58.89 - Other specfied aftercare (Approximate Flag)

Present on Admission (POA)
The code T45.8X5D is exempt from POA reporting.

  • Acquired aplastic anemia
  • Acquired red cell aplasia
  • Activated factor VII products adverse reaction
  • Adverse reaction to blood or blood product
  • Adverse reaction to blood plasma
  • Adverse reaction to food additive
  • Adverse reaction to human fibrinogen
  • Adverse reaction to macromolecular blood substitutes
  • Adverse reaction to packed red cells
  • Adverse reaction to whole blood
  • Albumin solution adverse reaction
  • Allergic reaction to chemical
  • Antibody mediated acquired pure red cell aplasia caused by erythropoiesis stimulating agent
  • Antithrombin III adverse reaction
  • Blood clotting factor adverse reaction
  • Blood derivative adverse reaction
  • Cation exchange resin adverse reaction
  • Cyanocobalamin adverse reaction
  • Desferrioxamine adverse reaction
  • Desferrioxamine adverse reaction
  • Desferrioxamine retinopathy
  • Dextran adverse reaction
  • Dextran pseudoallergy
  • Dimercaprol adverse reaction
  • Drug-induced retinopathy
  • Edetate adverse reaction
  • Epoetin alfa adverse reaction
  • Epoetin beta adverse reaction
  • Erythropoietin adverse reaction
  • Factor V concentrate products adverse reaction
  • Factor VII concentrate products adverse reaction
  • Factor VIII by-passing fraction products adverse reaction
  • Factor VIII fraction products adverse reaction
  • Factor XI products adverse reaction
  • Factor XIII products adverse reaction
  • Folic acid adverse reaction
  • Folinic acid adverse reaction
  • Foreign body dermatosis
  • Gelatin adverse reaction
  • Hemostatic adverse reaction
  • Hetastarch adverse reaction
  • Hetastarch pseudoallergy
  • Human protein-induced anaphylaxis
  • Hydroxocobalamin adverse reaction
  • Ion exchange resin adverse reaction
  • Pentastarch adverse reaction
  • Pentastarch pseudoallergy
  • Perfluorochemical adverse reaction
  • Plasma protein solution adverse reaction
  • Plasma substitutes adverse reaction
  • Polyvinyl pyrrolidone disease
  • Sodium calcium edetate adverse reaction
  • Sodium cellulose phosphate adverse reaction
  • Toxic retinopathy
  • Trientine adverse reaction
  • Vitamin B12 preparation adverse reaction
  • Vitamin B12 preparation adverse reaction
  • Von Willebrand factor products adverse reaction

Information for Patients

Drug Reactions

Also called: Side effects

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions.

One problem is interactions, which may occur between

  • Two drugs, such as aspirin and blood thinners
  • Drugs and food, such as statins and grapefruit
  • Drugs and supplements, such as ginkgo and blood thinners
  • Drugs and diseases, such as aspirin and peptic ulcers

Interactions can change the actions of one or both drugs. The drugs might not work, or you could get side effects.

Side effects are unwanted effects caused by the drugs. Most are mild, such as a stomach aches or drowsiness, and go away after you stop taking the drug. Others can be more serious.

Drug allergies are another type of reaction. They can be mild or life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is more rare.

When you start a new prescription or over-the-counter medication, make sure you understand how to take it correctly. Know which other medications and foods you need to avoid. Ask your health care provider or pharmacist if you have questions.

  • Angioedema (Medical Encyclopedia)
  • Drug allergies (Medical Encyclopedia)
  • Drug-induced diarrhea (Medical Encyclopedia)
  • Drug-induced tremor (Medical Encyclopedia)
  • Taking multiple medicines safely (Medical Encyclopedia)

[Read More]

ICD-10 Footnotes

General Equivalence Map Definitions
The ICD-10 and ICD-9 GEMs are used to facilitate linking between the diagnosis codes in ICD-9-CM and the new ICD-10-CM code set. The GEMs are the raw material from which providers, health information vendors and payers can derive specific applied mappings to meet their needs.

  • Approximate Flag - The approximate flag is on, indicating that the relationship between the code in the source system and the code in the target system is an approximate equivalent.
  • No Map Flag - The no map flag indicates that a code in the source system is not linked to any code in the target system.
  • Combination Flag - The combination flag indicates that more than one code in the target system is required to satisfy the full equivalent meaning of a code in the source system.

Present on Admission
The Present on Admission (POA) indicator is used for diagnosis codes included in claims involving inpatient admissions to general acute care hospitals. POA indicators must be reported to CMS on each claim to facilitate the grouping of diagnoses codes into the proper Diagnostic Related Groups (DRG). CMS publishes a listing of specific diagnosis codes that are exempt from the POA reporting requirement.

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