2027 ICD-10-CM Diagnosis Code R90.82White matter disease, unspecified

ICD-10-CM Codes›R00–R99›R90-R94›R90

ICD-10-CM R90.82
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

R90.82 is a billable ICD-10-CM diagnosis code for white matter disease, unspecified. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 91 through 93. As a symptom code, it should not be used as a principal diagnosis once a related definitive diagnosis has been established. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Abnormal findings without diagnosis.

Code Identity

ICD-10-CM Code
R90.82
Billable Status
Yes — Valid for Submission
Code Describes
White matter disease, unspecified
Short Description
White matter disease, unspecified
Same as the full description in the CMS dataset.
Parent Code
R90.8
Other abnormal findings on diagnostic imaging of central nervous system

Code Classification

ChapterR00–R99Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
SectionR90-R94Abnormal findings on diagnostic imaging and in function studies, without diagnosis
CategoryR90Abnormal findings on diagnostic imaging of central nervous system
This CodeR90.82White matter disease, unspecified

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy
  • Cerebral degeneration due to neoplastic disease
  • Encephalopathy due to vitamin B12 deficiency
  • Infantile neurodegeneration, progressive spasticity, intellectual disability, white matter lesions syndrome
  • Leukoaraiosis on imaging of brain
  • Silent white matter disease due to vascular disease
  • Toxic leukoencephalopathy
  • White matter disease
  • White matter disease due to anti-phospholipid syndrome
  • White matter disease due to microglioma
  • White matter disorder caused by infection
  • White matter disorder co-occurrent and due to cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy
  • White matter disorder due to ischemia
  • White matter disorder due to nutritional deficiency
  • White matter disorder due to vascular abnormality
  • White matter disorder due to vitamin B12 deficiency

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to R90.82: its own notes plus those printed at block R90-R94 and Chapter 18. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From Block R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis applies to 64 codes
  • nonspecific abnormal findings on diagnostic imaging by computerized axial tomography [CAT scan]
  • nonspecific abnormal findings on diagnostic imaging by magnetic resonance imaging [MRI][NMR]
  • nonspecific abnormal findings on diagnostic imaging by positron emission tomography [PET scan]
  • nonspecific abnormal findings on diagnostic imaging by thermography
  • nonspecific abnormal findings on diagnostic imaging by ultrasound [echogram]
  • nonspecific abnormal findings on diagnostic imaging by X-ray examination

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From Block R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis applies to 64 codes
  • abnormal findings on antenatal screening of mother (O28.-)
  • diagnostic abnormal findings classified elsewhere - see Alphabetical Index

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Chapter 18 (R00-R99) Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified applies to 774 codes
  • abnormal findings on antenatal screening of mother (O28.-)
  • certain conditions originating in the perinatal period (P04-P96)
  • signs and symptoms classified in the body system chapters
  • signs and symptoms of breast (N63, N64.5)

Notes

General instructions on how these codes are used.

From Chapter 18 (R00-R99) Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified applies to 774 codes
  • This chapter includes symptoms, signs, abnormal results of clinical or other investigative procedures, and ill-defined conditions regarding which no diagnosis classifiable elsewhere is recorded.
  • Signs and symptoms that point rather definitely to a given diagnosis have been assigned to a category in other chapters of the classification. In general, categories in this chapter include the less well-defined conditions and symptoms that, without the necessary study of the case to establish a final diagnosis, point perhaps equally to two or more diseases or to two or more systems of the body. Practically all categories in the chapter could be designated 'not otherwise specified', 'unknown etiology' or 'transient'. The Alphabetical Index should be consulted to determine which symptoms and signs are to be allocated here and which to other chapters. The residual subcategories, numbered .8, are generally provided for other relevant symptoms that cannot be allocated elsewhere in the classification.
  • The conditions and signs or symptoms included in categories R00-R94 consist of:
  • (a) cases for which no more specific diagnosis can be made even after all the facts bearing on the case have been investigated;
  • (b) signs or symptoms existing at the time of initial encounter that proved to be transient and whose causes could not be determined;
  • (c) provisional diagnosis in a patient who failed to return for further investigation or care;
  • (d) cases referred elsewhere for investigation or treatment before the diagnosis was made;
  • (e) cases in which a more precise diagnosis was not available for any other reason;
  • (f) certain symptoms, for which supplementary information is provided, that represent important problems in medical care in their own right.

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name R90.82, its category, or a range that includes it.

Excludes1 1

These codes carry an Excludes1 note naming R90.82: they are not reported together with it, unless the two conditions are unrelated.

  • R22 Localized swelling, mass and lump of skin and subcutaneous tissue
    abnormal findings on diagnostic imaging (R90-R93) names R90-R93, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR SYM017
Abnormal findings without diagnosis
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Leukoencephalopathies

    any of various diseases affecting the white matter of the central nervous system.

Convert R90.82 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
793.0 Nonsp abn fd-skull/head
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About R90.82Overview

What is the ICD-10 code for white matter disease, unspecified?

The ICD-10-CM code for white matter disease, unspecified is R90.82 (sometimes written as R9082). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is R90.82 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report white matter disease, unspecified on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does R90.82 group to?

When white matter disease, unspecified is the principal diagnosis on an inpatient stay, it groups to MS-DRG 91, 92, 93, with relative weights from 0.7783 to 1.7050 depending on complications. Higher weights mean higher Medicare reimbursement.

Can R90.82 be a principal diagnosis?

Use it with care. This is a symptom code, so once a definitive diagnosis explaining the white matter disease, unspecified is established, that condition takes the principal position instead.

Can R90.82 be reported with a code from O28?

Not as a rule. The Excludes1 note at block R90-R94, which applies to R90.82, lists "abnormal findings on antenatal screening of mother (O28.-)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).