2027 ICD-10-CM Diagnosis Code R80.3Bence Jones proteinuria

ICD-10-CM Codes›R00–R99›R80-R82›R80

ICD-10-CM R80.3
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

R80.3 is a billable ICD-10-CM diagnosis code for bence Jones proteinuria. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 695 through 696. As a symptom code, it should not be used as a principal diagnosis once a related definitive diagnosis has been established. Coders also document this condition as bence Jones protein detected. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Proteinuria.

Code Identity

ICD-10-CM Code
R80.3
Billable Status
Yes — Valid for Submission
Code Describes
Bence Jones proteinuria
Short Description
Bence Jones proteinuria
Same as the full description in the CMS dataset.
Parent Code
Proteinuria

Code Classification

ChapterR00–R99Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
SectionR80-R82Abnormal findings on examination of urine, without diagnosis
CategoryR80Proteinuria
This CodeR80.3Bence Jones proteinuria

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Bence Jones protein detected
  • Bence-Jones proteinuria
  • Intermittent Bence Jones proteinuria
  • Light-chain proteinuria
  • Persistent Bence Jones proteinuria
  • Persistent proteinuria

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to R80.3: its own notes plus those printed at R80, block R80-R82, and Chapter 18. A note printed at a category, block or chapter applies to every code under it.

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From R80 Proteinuria applies to 6 codes
  • gestational proteinuria (O12.1-)
From Block R80-R82 Abnormal findings on examination of urine, without diagnosis applies to 25 codes
  • abnormal findings on antenatal screening of mother (O28.-)
  • diagnostic abnormal findings classified elsewhere - see Alphabetical Index
  • specific findings indicating disorder of amino-acid metabolism (E70-E72)
  • specific findings indicating disorder of carbohydrate metabolism (E73-E74)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Chapter 18 (R00-R99) Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified applies to 774 codes
  • abnormal findings on antenatal screening of mother (O28.-)
  • certain conditions originating in the perinatal period (P04-P96)
  • signs and symptoms classified in the body system chapters
  • signs and symptoms of breast (N63, N64.5)

Notes

General instructions on how these codes are used.

From Chapter 18 (R00-R99) Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified applies to 774 codes
  • This chapter includes symptoms, signs, abnormal results of clinical or other investigative procedures, and ill-defined conditions regarding which no diagnosis classifiable elsewhere is recorded.
  • Signs and symptoms that point rather definitely to a given diagnosis have been assigned to a category in other chapters of the classification. In general, categories in this chapter include the less well-defined conditions and symptoms that, without the necessary study of the case to establish a final diagnosis, point perhaps equally to two or more diseases or to two or more systems of the body. Practically all categories in the chapter could be designated 'not otherwise specified', 'unknown etiology' or 'transient'. The Alphabetical Index should be consulted to determine which symptoms and signs are to be allocated here and which to other chapters. The residual subcategories, numbered .8, are generally provided for other relevant symptoms that cannot be allocated elsewhere in the classification.
  • The conditions and signs or symptoms included in categories R00-R94 consist of:
  • (a) cases for which no more specific diagnosis can be made even after all the facts bearing on the case have been investigated;
  • (b) signs or symptoms existing at the time of initial encounter that proved to be transient and whose causes could not be determined;
  • (c) provisional diagnosis in a patient who failed to return for further investigation or care;
  • (d) cases referred elsewhere for investigation or treatment before the diagnosis was made;
  • (e) cases in which a more precise diagnosis was not available for any other reason;
  • (f) certain symptoms, for which supplementary information is provided, that represent important problems in medical care in their own right.

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name R80.3, its category, or a range that includes it.

Excludes2 2

These codes carry an Excludes2 note naming R80.3: its condition is not part of those codes, and both may be reported when the patient has both.

  • N39 Other disorders of urinary system
    proteinuria NOS (R80.-) names R80.-, which includes this code
  • Block R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
    abnormal findings on examination of urine, without diagnosis (R80-R82) names R80-R82, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR GEN010
Proteinuria
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Proteinuria

    the presence of proteins in the urine, an indicator of kidney diseases.

Patient EducationClinical

Urine and Urination

Your kidneys make urine by filtering wastes and extra water from your blood. The waste is called urea. Your blood carries it to the kidneys. From the kidneys, urine travels down two thin tubes called ureters to the bladder. The bladder stores urine until you are ready to urinate.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert R80.3 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
791.0 Proteinuria
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About R80.3Overview

What is the ICD-10 code for bence Jones proteinuria?

The ICD-10-CM code for bence Jones proteinuria is R80.3 (sometimes written as R803). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is R80.3 (Proteinuria) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report bence Jones proteinuria on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does R80.3 group to?

When bence Jones proteinuria is the principal diagnosis on an inpatient stay, it groups to MS-DRG 696, 695, with relative weights from 0.6677 to 1.1136 depending on complications. Higher weights mean higher Medicare reimbursement.

Can R80.3 be a principal diagnosis?

Use it with care. This is a symptom code, so once a definitive diagnosis explaining the bence Jones proteinuria is established, that condition takes the principal position instead.

Can R80.3 be reported with a code from O12.1?

Not as a rule. The Excludes1 note at R80, which applies to R80.3, lists "gestational proteinuria (O12.1-)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).