2026 ICD-10-CM Diagnosis Code R46.4Slowness and poor responsiveness

ICD-10-CM CodesR00–R99R40-R46R46

ICD-10-CM R46.4
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

R46.4 is a billable ICD-10-CM diagnosis code for slowness and poor responsiveness. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 951. As a symptom code, it should not be used as a principal diagnosis once a related definitive diagnosis has been established. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Symptoms of mental and substance use conditions.

Code Identity

ICD-10-CM Code
R46.4
Billable Status
Yes — Valid for Submission
Code Describes
Slowness and poor responsiveness
Short Description
Slowness and poor responsiveness
Same as the full description in the CMS dataset.
Parent Code
Symptoms and signs involving appearance and behavior

Code Classification

ChapterR00–R99Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
SectionR40-R46Symptoms and signs involving cognition, perception, emotional state and behavior
CategoryR46Symptoms and signs involving appearance and behavior
This CodeR46.4Slowness and poor responsiveness

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Slowness and poor responsiveness

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Type 1 Excludes

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR SYM008
Symptoms of mental and substance use conditions
Default principal diagnosis: inpatient Yes · outpatient Yes

Convert R46.4 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
799.89 Ill-define condition NEC
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About R46.4Overview

What is the ICD-10 code for slowness and poor responsiveness?

The ICD-10-CM code for slowness and poor responsiveness is R46.4 (sometimes written as R464). It is billable on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

Is R46.4 (Symptoms and signs involving appearance and behavior) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report slowness and poor responsiveness on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does R46.4 group to?

When slowness and poor responsiveness is the principal diagnosis on an inpatient stay, it groups to MS-DRG 951 (other Factors Influencing Health Status), which carries a relative weight of 0.556. Higher weights mean higher Medicare reimbursement.

Can R46.4 be a principal diagnosis?

Use it with care. This is a symptom code, so once a definitive diagnosis explaining the slowness and poor responsiveness is established, that condition takes the principal position instead.

What is the ICD-9 equivalent of R46.4?

Under the General Equivalence Mappings, slowness and poor responsiveness converts to ICD-9-CM 799.89 (ill-define condition NEC). The mapping is approximate, so confirm the match fits the documentation.