2026 ICD-10-CM Diagnosis Code P74.5Transitory tyrosinemia of newborn

ICD-10-CM Codes›P00–P96›P70-P74›P74

ICD-10-CM P74.5
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

P74.5 is a billable ICD-10-CM diagnosis code for transitory tyrosinemia of newborn. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). Coders also document this condition as hypertyrosinemia. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified perinatal conditions.

Code Identity

ICD-10-CM Code
P74.5
Billable Status
Yes — Valid for Submission
Code Describes
Transitory tyrosinemia of newborn
Short Description
Transitory tyrosinemia of newborn
Same as the full description in the CMS dataset.
Parent Code
P74
Other transitory neonatal electrolyte and metabolic disturbances

Code Classification

ChapterP00–P96Certain conditions originating in the perinatal period
SectionP70-P74Transitory endocrine and metabolic disorders specific to newborn
CategoryP74Other transitory neonatal electrolyte and metabolic disturbances
This CodeP74.5Transitory tyrosinemia of newborn

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Hypertyrosinemia
  • Neonatal metabolic acidemia
  • Transient neonatal hypertyrosinemia

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Tyrosinemia
      • newborn, transitory

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR PNL013
Other specified and unspecified perinatal conditions
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Tyrosinemia

    an autosomal recessive inherited metabolic disorder caused by mutations in the fah, hpd, and tat genes. it is characterized by deficiency of one of the enzymes that are involved in the metabolism of tyrosine. it results in elevated blood tyrosine levels and accumulation of tyrosine and its byproducts in the liver, kidney, nervous system and other organs.

  • Tyrosinemia Type I|Type I Tyrosinemia

    tyrosinemia caused by mutations in the fah gene. it is characterized by deficiency of the enzyme fumarylacetoacetate hydrolase. it is the most severe form of tyrosinemia. signs and symptoms appear early in life and include failure to thrive, vomiting, diarrhea, jaundice, and bleeding tendency. it may result in liver and kidney failure. patients with this type of tyrosinemia may also have a predisposition for hepatocellular carcinoma.

  • Tyrosinemia Type II

    tyrosinemia caused by mutation(s) in the tat gene, encoding tyrosine aminotransferase. the inheritance is autosomal recessive.

Patient EducationClinical

Metabolic Disorders

Metabolism is the process your body uses to get or make energy from the food you eat. Food is made up of proteins, carbohydrates, and fats. Chemicals in your digestive system break the food parts down into sugars and acids, your body's fuel.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert P74.5 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
775.89 Neonat endo/met dis NEC
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About P74.5Overview

Is P74.5 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report transitory tyrosinemia of newborn on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What is the ICD-9 equivalent of P74.5?

Under the General Equivalence Mappings, transitory tyrosinemia of newborn converts to ICD-9-CM 775.89 (neonat endo/met dis NEC). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.