2027 ICD-10-CM Diagnosis Code P28.40Unspecified apnea of newborn

ICD-10-CM Codes›P00–P96›P19-P29›P28

ICD-10-CM P28.40
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

P28.40 is a billable ICD-10-CM diagnosis code for unspecified apnea of newborn. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 794. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 17 closely related codes. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Respiratory perinatal condition.

Code Identity

ICD-10-CM Code
P28.40
Billable Status
Yes — Valid for Submission
Code Describes
Unspecified apnea of newborn
Short Description
Unspecified apnea of newborn
Same as the full description in the CMS dataset.
Parent Code
P28.4
Other apnea of newborn

Code Classification

ChapterP00–P96Certain conditions originating in the perinatal period
SectionP19-P29Respiratory and cardiovascular disorders specific to the perinatal period
CategoryP28Other respiratory conditions originating in the perinatal period
This CodeP28.40Unspecified apnea of newborn

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Apnea
  • Apnea - anesthetic
  • Gastroesophageal reflux disease with apnea
  • Infantile apnea
  • Initial apnea
  • Late apnea
  • Neonatal apnea
  • Neonatal apnea due to neurological injury
  • Neonatal apneic attack
  • Neonatal primary apnea
  • Neonatal prolonged apnea
  • Neonatal recurrent apnea
  • Perinatal apneic spells
  • Recurrent apnea
  • Traumatic apnea

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to P28.40: its own notes plus those printed at P28.4, P28, and Chapter 16. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From Chapter 16 (P00-P96) Certain conditions originating in the perinatal period applies to 463 codes
  • conditions that have their origin in the fetal or perinatal period (before birth through the first 28 days after birth) even if morbidity occurs later

Applicable To

Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.

  • Apnea of newborn, NOS
  • Transient oxygen desaturation spells of newborn

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From P28.4 Other apnea of newborn applies to 5 codes
  • primary sleep apnea of newborn (P28.3-)
From Chapter 16 (P00-P96) Certain conditions originating in the perinatal period applies to 463 codes
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • tetanus neonatorum (A33)

Code Also

A second code may be needed to fully describe the condition; the note gives no sequencing direction.

From P28 Other respiratory conditions originating in the perinatal period applies to 19 codes
  • if applicable, congenital malformations of the respiratory system (Q30-Q34)

Notes

General instructions on how these codes are used.

From Chapter 16 (P00-P96) Certain conditions originating in the perinatal period applies to 463 codes
  • Codes from this chapter are for use on newborn records only, never on maternal records

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name P28.40, its category, or a range that includes it.

Excludes1 5

These codes carry an Excludes1 note naming P28.40: they are not reported together with it, unless the two conditions are unrelated.

  • J98 Other respiratory disorders
    newborn apnea (P28.4-) names P28.4-, which includes this code
  • R06.81 Apnea, not elsewhere classified
    apnea (of) newborn (P28.4-) names P28.4-, which includes this code
  • Z03.83 Encounter for observation for suspected conditions related to home physiologic monitoring device ruled out
    newborn apnea (P28.4-) names P28.4-, which includes this code
  • Z05.81 Observation and evaluation of newborn for suspected condition related to home physiologic monitoring device ruled out
    other newborn apnea (P28.4-) names P28.4-, which includes this code
  • P28.2 Cyanotic attacks of newborn
    apnea of newborn (P28.3- - P28.4-) names P28.3- - P28.4, which includes this code

Excludes2 1

These codes carry an Excludes2 note naming P28.40: its condition is not part of those codes, and both may be reported when the patient has both.

  • P28.3 Primary sleep apnea of newborn
    other apnea of newborn (P28.4-) names P28.4-, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR PNL006
Respiratory perinatal condition
Default principal diagnosis: inpatient Yes · outpatient Yes

Code History & ChangesHistory

Replacement P28.40 replaces the following previously assigned code(s):

  • P28.4 - Other apnea of newborn
FY 2023AddedAdded to the ICD-10-CM code setEffective October 1, 2022.
FY 2024–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About P28.40Overview

What is the ICD-10 code for unspecified apnea of newborn?

The ICD-10-CM code for unspecified apnea of newborn is P28.40 (sometimes written as P2840). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is P28.40 (Other apnea of newborn) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report unspecified apnea of newborn on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does P28.40 group to?

When unspecified apnea of newborn is the principal diagnosis on an inpatient stay, it groups to MS-DRG 794 (neonate with Other Significant Problems), which carries a relative weight of 1.4934. Higher weights mean higher Medicare reimbursement.

Is P28.40 a CC or MCC?

CMS lists P28.40 as a CC (complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 17 closely related codes in its exclusion list.