2026 ICD-10-CM Diagnosis Code P25.1Pneumothorax originating in the perinatal period

ICD-10-CM CodesP00–P96P19-P29P25

ICD-10-CM P25.1
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

P25.1 is a billable ICD-10-CM diagnosis code for pneumothorax originating in the perinatal period. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Respiratory perinatal condition.

Code Identity

ICD-10-CM Code
P25.1
Billable Status
Yes — Valid for Submission
Code Describes
Pneumothorax originating in the perinatal period
Short Description
Pneumothorax originating in the perinatal period
Same as the full description in the CMS dataset.
Parent Code
Interstitial emphysema and related conditions originating in the perinatal period

Code Classification

ChapterP00–P96Certain conditions originating in the perinatal period
SectionP19-P29Respiratory and cardiovascular disorders specific to the perinatal period
CategoryP25Interstitial emphysema and related conditions originating in the perinatal period
This CodeP25.1Pneumothorax originating in the perinatal period

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Acute pneumothorax
  • Air leaking from lung
  • Clicking pneumothorax
  • Closed pneumothorax
  • Familial spontaneous pneumothorax
  • Left pneumothorax
  • Neonatal pulmonary air leak
  • Perinatal pneumothorax
  • Pneumothorax
  • Primary spontaneous pneumothorax
  • Right pneumothorax
  • Spontaneous pneumothorax
  • Spontaneous pneumothorax due to respiratory disease

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Pneumothorax NOS
      • congenital
    • Pneumothorax NOS
      • perinatal period
    • Pneumothorax NOS
      • spontaneous NOS
        • newborn

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR PNL006
Respiratory perinatal condition
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Pneumothorax

    an accumulation of air or gas in the pleural cavity, which may occur spontaneously or as a result of trauma or a pathological process. the gas may also be introduced deliberately during pneumothorax, artificial.
  • Pneumothorax, Artificial

    injection of air or a more slowly absorbed gas such as nitrogen, into the pleural cavity to collapse the lung.
  • Pleural Cavity

    paired but separate cavity within the thoracic cavity. it consists of the space between the parietal and visceral pleura and normally contains a capillary layer of serous fluid that lubricates the pleural surfaces.
  • Grade 1 Neonatal Pneumothorax, AE|Grade 1 Neonatal Pneumothorax|Grade 1 Neonatal Pneumothorax, Adverse Event

    an adverse event in a newborn characterized by radiological evidence of pneumothorax; no clinical signs; no care change required.
  • Grade 1 Pneumothorax, CTCAE|Grade 1 Pneumothorax|Grade 1 Pneumothorax

    asymptomatic; clinical or diagnostic observations only; intervention not indicated
  • Grade 2 Neonatal Pneumothorax, AE|Grade 2 Neonatal Pneumothorax|Grade 2 Neonatal Pneumothorax, Adverse Event

    an adverse event in a newborn characterized by radiological evidence of pneumothorax; minor clinical signs; minor care change required (e.g. oxygen, increased monitoring).
  • Grade 2 Pneumothorax, CTCAE|Grade 2 Pneumothorax|Grade 2 Pneumothorax

    symptomatic; intervention indicated
  • Grade 3 Neonatal Pneumothorax, AE|Grade 3 Neonatal Pneumothorax|Grade 3 Neonatal Pneumothorax, Adverse Event

    an adverse event in a newborn characterized by radiological evidence of pneumothorax; with clinical signs; major care change required (e.g. chest drainage).
  • Grade 3 Pneumothorax, CTCAE|Grade 3 Pneumothorax|Grade 3 Pneumothorax

    sclerosis and/or operative intervention indicated; hospitalization indicated
  • Grade 4 Neonatal Pneumothorax, AE|Grade 4 Neonatal Pneumothorax|Grade 4 Neonatal Pneumothorax, Adverse Event

    a pneumothorax adverse event in a newborn characterized by life-threatening respiratory and/or hemodynamic compromise (e.g. tension pneumothorax); urgent major care change required.
  • Grade 4 Pneumothorax, CTCAE|Grade 4 Pneumothorax|Grade 4 Pneumothorax

    life-threatening consequences; urgent intervention indicated
  • Grade 5 Neonatal Pneumothorax, AE|Grade 5 Neonatal Pneumothorax|Grade 5 Neonatal Pneumothorax, Adverse Event

    a pneumothorax adverse event in a newborn which results in death.
  • Grade 5 Pneumothorax, CTCAE|Grade 5 Pneumothorax|Grade 5 Pneumothorax

    death
  • Neonatal Pneumothorax, AE|Neonatal Pneumothorax|Neonatal Pneumothorax, Adverse Event|Neonatal pneumothorax

    an adverse event in a newborn characterized by a collection of air or other gas between the visceral and parietal pleura.
  • Pneumothorax

    abnormal presence of air in the pleural cavity.
  • Pneumothorax, CTCAE|Pneumothorax|Pneumothorax|Pneumothorax

    a disorder characterized by abnormal presence of air in the pleural cavity resulting in the collapse of the lung.

Patient EducationClinical

Pleural Disorders

Your pleura is a large, thin sheet of tissue that wraps around the outside of your lungs and lines the inside of your chest cavity. Between the layers of the pleura is a very thin space. Normally it's filled with a small amount of fluid.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert P25.1 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
770.2 NB interstit emphysema
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About P25.1Overview

Is P25.1 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report pneumothorax originating in the perinatal period on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What is the ICD-9 equivalent of P25.1?

Under the General Equivalence Mappings, pneumothorax originating in the perinatal period converts to ICD-9-CM 770.2 (NB interstit emphysema). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.